Hair and urine testing to assess drugs of abuse consumption in couples undergoing assisted reproductive technology (ART)

For the first time in Europe hair and urine testing have been applied to assess drugs of abuse consumption in couples undergoing assisted reproductive technology and the eventual association of toxic habits with other lifestyle, health status and sociodemographic factors was also investigated. Couples attending five assisted reproduction centers in Rome were invited to join the study. When they presented at the Centre for the visit, they were asked to answer a structured questionnaire concerning sociodemographic characteristics and lifestyle habits, and at the same time to provide hair and urine samples. Hair and urine testing for drugs of abuse, urinary profile of principal endogenous steroids involved in fertility process (testosterone, epitestosterone, androsterone, etiocholanolone and dehydroepiandrosterone) and of alcohol and tobacco smoke biomarkers were performed with validated methodologies. Of the 594 enrolled individuals (297 couples), 352 (164 couples and 24 single individuals from the couple) completed the questionnaire and gave both hair and urine samples, apart from 3 bald men, who only gave urine samples. Urine testing showed an overall 4.8% (17 individuals) positivity to drugs of abuse: 4.2% to cannabinoids, 1.4% to cocaine and 0.85% to both drugs. Results of 4cm segment hair samples testing matched those from urine samples. Thus, taking together, results of urine and hair testing confirmed repeated use of cannabis, cocaine and both drugs in 3.7, 0.85 and 0.57% examined individuals, respectively. Drug consumers were in a statistically higher percentage active smokers and alcohol drinkers, less prone to physical activity and with a trend towards higher weight than non consumers. Finally, repeated drug consumption was associated with significant lower concentration of urinary testosterone in males and of urinary dehydroepiandrosterone in females. The findings of the present study confirm the suitability of urine testing to disclose recent drugs of abuse consumption and of hair analysis to verify repeated consumption. Association between different toxic habits and sedentary lifestyle is also substantiated by the obtained results in our cohort of couples attending assisted reproduction centers.     

Managing commingled remains from mass graves: considerations, implications and recommendations from a human rights case in Chile

This paper focuses on a little discussed part of Chilean history and the efforts to resolve Human Rights cases from the period 1973 to 1990. A case file is presented to illustrate the different stages, problems and solutions found in one particularly challenging case studied by the Special Unit of Identification of Detained and Missing (UEIDDDD) of the Human Rights Program of the Forensic Service, Chile, during the period 2006-2009. A major complication found in this example was the fact that the remains studied were commingled, and in addition, were mixed with remains that were not of medico-legal interest - deposited prior to and after the case in question, but within the same common grave. Multiple burials and the consequences of commingled skeletal human remains are reviewed, paying special attention to the roles that different agents related to these types of cases play, how they influence the decision making process and the outcomes that can be expected in commingled cases due to the complexities and challenges they present. Effective communication between prosecutors and forensic practitioners is vital to optimize the resources. Equally important is the relationship that is built between the practitioners and the victims' families regarding communication, information and expectations that both parties may have.     

Hyperbolic Time Discounting, Offender Time Preferences and Deterrence

Objectives

This study examines the phenomena of intertemporal decision making??decisions involving costs and benefits that occur at different points in time. Two models of intertemporal time discounting are the exponential and hyperbolic models. Previous work in behavioral economics and psychology is relied on to make the case that the discounting of delayed outcomes (both gains and losses) may be hyperbolic rather than exponential.

Methods

Data were collected from 478 university undergraduate students who responded to a hypothetical scenario involving drunk driving. The potential gains and losses of drunk driving were delayed at five different intervals from ??tonight?? to ??10?years from now??, respondents were also asked to provide estimates of both the risk they would get caught if they did drink and drive and the probability that they would drink and drive under the conditions described in the scenario.

Results

Our results imply that individuals have hyperbolic time preferences for both rewards and gains, and that??unlike severity, the effect of which may be muted by risk??these discount functions appear to be operating independently of changes in the risk certainty of detection. Consistent with hyperbolic discounting, for example, when the benefit of drinking and driving was delayed by 1?week the self-reported intention to drink and drive increased by nearly 10%, however, when the gain was delayed by one month, intentions to drink and drive increased by only 4%. A smaller effect was found for delayed costs.

Conclusions

Avenues for additional research include the possibility of negative discount rates and the implications of persons?? awareness of their discount rates.     

Nationalist Protests,Government Responses,and the Risk of Escalation in Interstate Disputes

While the existing literature emphasizes that elites often have incentives to pander to nationalist sentiment, much less attention has been paid to elite efforts to subdue popular nationalism, either to avoid domestic instability or international escalation. This article examines how different governments respond to nationalist protests and the resulting effects on the risk that interstate disputes will escalate to armed conflict. We argue that government responses to nationalist protests tend to vary in patterned ways across regime types. Nationalist protests present particular dangers in weakly institutionalized democracies, where demonstrations often pose serious threats of instability but are difficult or costly for the government to subdue, tempting or forcing leaders to escalate to appease domestic critics. We illustrate the theory with four cases representing a range of regime types: Vietnam, Cambodia, Thailand, and the Philippines.     

Animal liberation,American anti-terrorist culture and Denis Hennelly’s Bold Native

Since its birth in the last quarter of the twentieth century, the animal liberation movement has attempted to expose the transnational, global character of speciecism and institutionalised forms of exploitation. Within the American panorama, however, the “war against terror” following 9/11 had such a profound effect on (radical) activism at a legal and legislative level that the movement found itself in the position of having to reassess their focus, leading to theoretical and aesthetic responses to anti-terrorist rhetoric. The aim of this article is (1) to examine the manner by which anti-terrorist rhetoric affected the movement and how the movement appropriated such rhetoric to reinvent their own discourse, and (2) analyse the audiovisual semiotics employed by Denis Hennelly in his 2010 film, Bold Native, so as to address how issues central to the movement’s current struggle and assimilation of concepts such as “terrorism” and “patriotism” translate at an aesthetic level.     

A method for calculating the strength of evidence associated with an earwitness's claimed recognition of a familiar speaker

The present paper proposes and demonstrates a method for assessing strength of evidence when an earwitness claims to recognize the voice of a speaker who is familiar to them. The method calculates a Bayes factor that answers the question: What is the probability that the earwitness would claim to recognize the offender as the suspect if the offender was the suspect versus what is the probability that the earwitness would claim to recognize the offender as the suspect if the offender was not the suspect but some other speaker from the relevant population? By “claim” we mean a claim made by a cooperative earwitness not a claim made by an earwitness who is intentionally deceptive. Relevant data are derived from naïve listeners' responses to recordings of familiar speakers presented in a speaker lineup. The method is demonstrated under recording conditions that broadly reflect those of a real case.