Using EHRs to design drug repositioning trials: A devolved approach to data protection

One area where the application of data protection law has proven complex is in relation to the secondary usage of health data in EHRs for medical research. Here the tension between the privacy interests of patients and the risk of harm if such sensitive data are compromised, and on the other side, the potential societal value of utilizing the data for the benefit of medical science, is especially striking. In this paper, we consider the applicable provisions of the EU Data Protection Directive, and outline a general approach to patient data handling for research, which we believe to be compatible with relevant legal and ethical requirements. We then illustrate and apply this by reference to a specific EU FP7 project, involving EHR data processing to select patients for clinical pharmaceutical trials. After introducing the project (PONTE), we explain the ‘devolved’ data protection architecture it employs and provide a legal evaluation.     

Determinants of national patent ownership by public research organisations and universities

This paper focuses on the question of whether the national production functions of patents owned by universities and public research organisations (PROs) differ. We use Eurostat patent and R&D data broken down by institutional sector for the European Union 27 and other countries in years 1982–2007, and we estimate dynamic panel models. The impact of R&D expenditure on patent ownership is higher for PROs than for universities. University patent ownership activity is dependent on business funding, while PRO patent ownership is not. We recommend a reversal of the current decline of PRO R&D expenditure and discuss whether PROs perform better at macroeconomic level vis a vis universities.     

No More! Women Reporting Intimate Partner Violence in Mexico

An analysis of the National Survey of Violence Against Women (2006) in Mexico was performed to estimate the prevalence and the associated factors of women suffering intimate partner violence (IPV) that report their aggressor by severity of violence. Women aged 15 years or older who reported IPV were analyzed by using logistic regression models. Prevalence of IPV was 33.33 %, 64.11 % of them were classified as non-severe violence (NSV) and 35.89 % as severe violence (SV). Women with SV reported the aggressor more often (24.69 % vs. 6.08 % of NSV). Variables associated with reporting the aggressor for both NSV and SV were having children living in the household, higher socioeconomic status, frequent alcohol consumption by the partner, and health personnel informing women that they were experiencing IPV. We can conclude that a low percentage of women reported IPV. Greater efforts should be made to empower women so they can effectively execute their right to live a life free of violence.     

A free market bailout alternative?

It has been more than 3 years since the collapse of the investment bank Lehman Brothers and the beginning of the Troubled Asset Relief Program. Most recently, the sovereign debt crisis in Europe has led to the bailout of the governments of Ireland, Portugal and Greece. A main reason behind these bailouts is to support European banks loaded with government bonds on their balance sheet. In this article we analyze the detrimental consequences of the public bailout in 2008 and argue that a free market alternative existed. The alternative of a private bailout outlined in this article, consisting of the conversion of liabilities into equity and a private capital increase, largely avoids the problems of a public bailout. Similarly, a public bailout of governments of the Eurozone to sustain banks may be detrimental.     

Determination of Acetamiprid and IM‐1‐2 in PostMortem Human Blood,Liver, Stomach Contents by HPLC‐DAD

An HPLC‐DAD method was developed to detect and quantify a neonicotinoid insecticide acetamiprid (ATP) and its metabolite IM‐1‐2 in autopsy samples of a fatal intoxication case. The postmortem blood and tissue distribution of ATP and IM‐1‐2 was determined for the first time. The method showed acceptable precisions and recoveries with relative standard deviations of <10% for ATP level and 1.38 % for IM‐1‐2. The detection and quantification limits for ATP were 0.015 μg/mL and 0.030 μg/mL for blood and were 0.035 μg/g and 0.050 μg/g for liver samples, respectively. The mean contents of ATP were 0.79 μg/g in the liver, 47.35 μg/g in the stomach contents and 2.7 μg/mL in the blood. IM‐1‐2 content was 17.0 μg/g in the stomach contents. ATP and IM‐1‐2 were not detected in the urine. The presence of ATP and IM‐1‐2 in the samples was confirmed by GC‐MS. The method can be exploited in future forensic casework.     

Differences in Physical Fitness and Body Composition Between Active and Sedentary Adolescents: A Systematic Review and Meta-Analysis

Journal of Youth and Adolescence - Previous research analyzing the differences in physical fitness and body composition between active and sedentary adolescents aged 12–16 has not provided...     

First Generation in Chilean Higher Education: Tension between Access and Inclusion in a Segmented University System

We analysed the Chilean university student selection processes, comparing ‘First Generation’ and ‘Continuist’ students, using the Chilean Higher Education population databases (2000–2015). Findings confirm that 60 percent of participants in the selection process are First Generation students. The data registers an increasing self-exclusion phenomenon. Of the students who did not take the selection test after enrolling, 80 percent are First Generation and 18 are enrolled in a selective university, compared to 44 in the Continuist conglomerate. These differences may be explained by cultural capital in the Bourdieu sense, in conjunction with a diversified, massified and marketalised higher education system.     

Hungarian Language and Law: Developing a Grammar for Social Inclusion,a Vocabulary for Political Emancipation. Special Issue (IJSL)—Editorial Preface

International Journal for the Semiotics of Law - Revue internationale de Sémiotique juridique - Having been invited by editor-in-chief, Professor Anne Wagner, to edit the present special...