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Sudden unexpected death in epilepsy: neuropathologic findings   总被引:4,自引:0,他引:4  
Sudden unexpected death in epilepsy refers to sudden death of an individual with a clinical history of epilepsy, in whom a postmortem examination fails to uncover a gross anatomic, toxicologic, or environmental cause of death. Evidence of terminal seizure activity may not be present. One to two percent of natural deaths certified by the medicolegal death investigator are attributed to epilepsy. Detailed microscopic examination of the brain has increasingly afforded the identification of structural changes representative of epileptogenic foci. The authors present 70 cases of death attributed to sudden unexpected death in epilepsy. These cases were classified as follows: individuals who lacked a gross brain lesion, those who had a brain lesion demonstrable at autopsy, and those who lacked neuropathologic evaluation because of decomposition or because only an external examination was done. All of the subjects had a clinical history of seizures. The authors confirm that various microscopic findings, including neuronal clusters, increased perivascular oligodendroglia, gliosis, cystic gliotic lesions, decreased myelin, cerebellar Bergmann's gliosis, and folial atrophy, are present in a higher percentage of the brains of sudden unexpected death in epilepsy subjects than in the brains of age- and sex-matched control subjects.  相似文献   
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David Rapoport's concept of Four Waves of terrorism, from Anarchist terrorism in the 1880s, through Nationalist and Marxist waves in the early and mid-twentieth century, to the present Religious Wave, is one of the most influential concepts in terrorism studies. However, this article argues that thinking about different types of terrorism as strains rather than waves better reflects both the empirical reality and the idea that terrorists learn from and emulate each other. Whereas the notion of waves suggests distinct iterations of terrorist violence driven by successive broad historical trends, the concept of strains and contagion emphasizes how terrorist groups draw on both contemporary and historical lessons in the development of their tactics, strategies, and goals. The authors identify four distinct strains in total—Socialist, Nationalist, Religious, and Exclusionist—and contend that it is possible to trace each strain back to a “patient zero” active in the 1850s.  相似文献   
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Forensic investigators routinely deploy side‐scan sonar for submerged body searches. This study adds to the limited body of literature by undertaking a controlled project to understand how variables affect detection of submerged bodies using side‐scan sonar. Research consisted of two phases using small and medium‐sized pig (Sus scrofa) carcasses as proxies for human bodies to investigate the effects of terrain, body size, frequency, swath width, and state of decomposition. Results demonstrated that a clear, flat, sandy pond floor terrain was optimal for detection of the target as irregular terrain and/or vegetation are major limitations that can obscure the target. A higher frequency towfish was preferred for small bodies, and a 20 m swath width allowed greater visibility and easier maneuverability of the boat in this environment. Also, the medium‐sized carcasses were discernable throughout the 81‐day study period, indicating that it is possible to detect bodies undergoing decomposition with side‐scan sonar.  相似文献   
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The article engages a critical analysis of liberal theory in the context of transnational migration. Normative arguments provided by liberal-cosmopolitan and liberal-communitarian authors are contrasted. While sympathetic to such approaches, we argue that traditional liberal theory has attempted to downplay the contingency and resultant ambiguity of many of its moral precepts. Historically contingent borders underpin neat universal categories like "citizen" and "refugee," which fail to reflect the diverse and contested experiences of migration. But such ambiguities need not undermine liberal approaches. Indeed, a proper engagement with the problematic and uncertain realities of migration can provide a spur to a more thoroughgoing ethical praxis. We draw on the philosophical pragmatism of Richard Rorty to outline an approach to migration that remains open to the contingent construction of terms like "migrant,""refugee," and "asylum-seeker." By extending Rorty's concept of sentimental education, we provide an imaginative and politically challenging set of agendas for the ethics of migration.  相似文献   
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Governments prioritize some rights over others because of policy constraints. We ask whether differential disability policy priorities can readdress other unrealized rights when applied to services for people with disabilities in boarding houses in Australia. The housing is inappropriate to their support needs and breaches their immediate right to unsegregated housing. Findings about the government-funded support showed that their well-being improved, but the housing increased their support needs and reduced their eligibility for suitable housing, implying that support policies that prioritize progressive realization rights are not successful where immediate realization rights to housing remain unaddressed. These findings about the negative social outcomes from ignoring human rights hierarchies have implications for policy priorities.  相似文献   
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This article explores the claims of Russian officials that US assessments of economic and political developments in Russia, particularly those of Freedom House (FH), are excessively critical and often used to justify global dominance. To assess the validity of such claims, three different influences are considered: culture, power, and special interests. The article finds that all three, each with roots in the cold war, play a role in shaping assessments of Russia and help to explain why FH's analysis of Russia is more critical than the analysis of other organizations. The politics of special interests is found to be particularly influential and reflects the interests of US national security policies and priorities. Such priorities are also linked to a politics of memory derived from the cold war, which often influences perceptions of Russia as a threat rather than as a potential partner.  相似文献   
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Privatisation is widely promoted as a means of improving economic performance in developing countries. However, the policy remains controversial and the relative roles of ownership and other structural changes, such as competition and regulation, in promoting economic performance remain uncertain. This article reviews the main empirical evidence on the impact of privatisation on economic performance in developing economies. The evidence suggests that if privatisation is to improve performance over the longer term, it needs to be complemented by policies that promote competition and effective state regulation, and that privatisation works best in developing countries when it is integrated into a broader process of structural reform.  相似文献   
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