A Nation of Sceptics? The Czech EU Accession Referendum of 13–14 June 2003

The Czech Republic's 13–14 June 2003 referendum on accession to the European Union was the seventh of nine held in candidate states due to join the EU on 1 May 2004. Despite the presence of two strong Eurosceptic parties and the perceived Euroscepticism of Czech public opinion, the pro-accession camp scored a convincing victory. This account analyses the historical, political and institutional context of the referendum and the campaign. It concludes that despite high elite contention over the EU and the overwhelming resources advantage of the ‘Yes’ camp, Czech voters were minimally influenced by the campaign. Rather, they took their cue from longstanding positive linkages of ‘Europe’ with democracy, market reform and Czech identity.     

Coup,riot, war: How political institutions and ethnic politics shape alternative forms of political violence

This article explores how different types of governance systems shape different forms of political violence. We identify four governance types by combining the “institutional” dimension of coalition size represented by a minimum winning coalition (MWC) and the “ethno-political” dimension represented by the size of ethnic groups participating in the governing coalition. This study hypothesizes that (a) an exclusive system (small MWC; narrow-based ethnic coalition) is likely to engender civil war, (b) an oversized system (small MWC; broad-based ethnic coalition) is likely to generate a coup, and (c) an undersized system (large MWC; narrow-based ethnic coalition) is likely to stimulate riots or protests. Statistical analyses confirm all three hypotheses, implying that opposition groups choose alternative forms of conflict that maximize their chances of accessing power under different governance configurations. The article concludes by identifying three possible paths toward inclusive governance and suggesting that institutional reform before ethnic inclusion makes a transition toward inclusive governance far less dangerous.     

The Abraham Accords and Religious Tolerance: Three Tales of Faith-Based Foreign-Policy Agenda Setting

How do religious tolerance and religious freedom affect foreign policy? How are they institutionalized across the signatories of the Abraham Accords? This article examines foreign policy agenda setting of religious tolerance in the United States, Israel, and the United Arab Emirates. In the first section, the article analyzes discursive representations of the common roots of the three monotheistic religions and identifies recurrent tropes that highlight idealistic undertones in the Abraham Accords Declaration. In the following section, it critically examines the nexus between domestic and international politics and assesses the compatibility between social and public policy and foreign-policy agenda setting centered on interfaith diplomacy and dialogue. While this article acknowledges Donald Trump's and previous US presidents’ contributions to the advancement of international religious freedom, it argues that Trump's conflicting standards and selective approaches to foreign policy and human rights preceding the agreement have failed to promote constructive relations for furthering faith-based diplomacy. This article suggests that while the United States and the UAE laid the groundwork for promoting religious freedom and tolerance leading up to the Abraham Accords, projecting a coherent foreign-policy narrative across these contexts is hampered by institutional, legal, and political considerations.     

DNA Typing for the Identification of Old Skeletal Remains from Korean War Victims*

Abstract: The identification of missing casualties of the Korean War (1950–1953) has been performed using mitochondrial DNA (mtDNA) profiles, but recent advances in DNA extraction techniques and approaches using smaller amplicons have significantly increased the possibility of obtaining DNA profiles from highly degraded skeletal remains. Therefore, 21 skeletal remains of Korean War victims and 24 samples from biological relatives of the supposed victims were selected based on circumstantial evidence and/or mtDNA‐matching results and were analyzed to confirm the alleged relationship. Cumulative likelihood ratios were obtained from autosomal short tandem repeat, Y‐chromosomal STR, and mtDNA‐genotyping results, and mainly confirmed the alleged relationship with values over 10⁵. The present analysis emphasizes the value of mini‐ and Y‐STR systems as well as an efficient DNA extraction method in DNA testing for the identification of old skeletal remains.     

Simple and highly effective DNA extraction methods from old skeletal remains using silica columns

The recovery of DNA data from old skeletal remains is often difficult due to degraded and very low yield of extracted DNA and the presence of PCR inhibitors. Herein, we compared several silica-based DNA extraction methods from artificially degraded DNA, DNA with PCR inhibitors and DNA from old skeletal remains using quantitative real-time PCR. We present a modified large-scale silica-based extraction combined with complete demineralization, that enables maximum DNA recovery and efficient elimination of PCR inhibitors. This is performed with high concentration of EDTA solution for demineralization of bone powder followed by QIAamp^® spin columns and buffers from the QIAquick^® PCR purification kit. We have successfully used this modified technique to perform STR analysis for 55-year-old skeletal remains. The results of this study will contribute to solve the forensic cases dealing with skeletal remains.     

Development of a specific fragment pattern-based quadrupole-Orbitrap mass spectrometry method to screen adulterated products of phosphodiesterase-5 inhibitors and their analogues

Recently, adulterated supplements with phosphodiesterase-5 inhibitors (PDE-5i) have frequently observed. New synthetic analogues obtained from the chemical modification of parent compounds are frequently found in illicit products despite continuous efforts to inspect for these adulterants. A rapid and accurate method based on quadrupole-Orbitrap mass spectrometry was developed for simultaneously confirming and quantifying 85 PDE-5i and derived analogues present in illicit products for erectile dysfunction (ED). Common ions of PDE-5i according to their similar structures were proposed based on MS/MS fragmentations. These common ions could be an important diagnosis of their presence targets or new emerging analogues in supplements. Several validation parameters were employed, resulting in a limit of detection and quantification of 0.09–8.55 ng/mL and 0.24–17.10 ng/mL, respectively. The linear correlation coefficient (r²) was higher than 0.995, and mean recoveries of target compounds were in the range of 82–118%. A total of 187 illicit products, obtained from on/offline markets over a period of 3 years (2015–2017), were screened by the established method. Approximately 53% of them were adulterated with PDE-5i or derived analogues at concentrations of 0.1–726.0 mg/g in the illicit products. In the interests of public health, this study describes a rapid and accurate method to determine PDE-5i and new emerging analogues in adulterated products.     

Socio-cultural aspects of the relationship between the EU and East Asia, with particular reference to China

This paper presents a comparative study about words and about sovereignty; about the ancestry of the words that construct the discourse of sovereignty in the context of China; about the analysis and interpretation of the civic discourse and the rhetoric that construct Chinese sovereignty in the field of international relations and foreign policy, and about the consequences of this analysis and interpretation for the formulation of EU foreign policy with regard to East Asia, especially China, and the United States, as well as the feedback that notions of sovereignty have on the construction of Chinese civic discourse. For many contemporary Chinese thinkers, China should modernise without repeating the process of modernism, should leap over the system of values established by the Enlightenment that seemed to justify imperialism, and develop an economy and institutions that would serve to create wealth and to raise the standard of living of the population, without imposing values that are advantageous to a “West” that is already wealthy. They have identified a cultural dissidence within developed societies that advocates the values of postmodernism as a way of rejecting the values of modernism. In this context, they advocate the possibility of modernising their society without having to accept the imposition of values that originated in societies that have already begun to question them. In this way, China could reach postmodernism in a relatively short period of history without having to pass through the traumas that characterised the development of modernism in the “West” over a period of centuries (it would be difficult not to discern echoes of Mao Zedong’s “Great Leap Forward” in these Chinese versions of the postmodernist paradigm). The communicative strategy to be adopted by the EU in the rhetorical construction of its dialogue with China should be fully cognizant of and sensitive to the criteria of China’s moral order as outlined in this study and specified in the Five Principles (mutual respect for sovereignty and territorial integrity; non-aggression; non-interference in each other’s internal affairs; equality and mutual benefit; and peaceful coexistence), the Spirit of Shanghai and the ASEAN Way, with special emphasis on mutual recognition, parity of esteem, and mutual benefit. Any other discourse will be perceived semiotically as unilateralist and exploitative. Respect for diversity is paramount, and the ability to harmonise diversity is a major function of Chinese political and cultural thought. “Harmony” and “peace” are the same word in classical Chinese: hé ( hépíng is the modern word for “peace” and héshēng is the modern word for “harmony”). As a result, any practice that produced harmony, such as music or cooking, was a form of training for maintaining peace, social cohesion and solidarity in society (or among nations).

Analysis of the impurities in the methamphetamine synthesized by three different methods from ephedrine and pseudoephedrine

Organic impurities of methamphetamine may show different patterns by synthesis. In the present study, we tried to find the impurities reflecting the conditions of synthesis by comparing impurity patterns of the methamphetamine samples synthesized by different methods. Sixteen methamphetamine samples were synthesized from ephedrine and pseudoephedrine by the three different manufacturing methods of Emde, Nagai and Moscow. The synthesized samples were extracted with ethyl acetate containing four internal standards, and the patterns of the organic impurities were investigated by GC-MS and GC-FID . Through the investigation, we found 10 peaks appearing in the latter part of GC chromatograms are characteristic to synthesis. The areas of the selected peaks were converted to the variables suitable for the statistical calculation, and the synthesized samples could be classified into four groups through the resultant cluster analysis.     

Confucian bioethics and cross-cultural considerations in health care decision-making

This article discusses the similarities and differences between Beauchamp and Childress's principlism and Confucian bioethics in terms of autonomy, beneficence, nonmaleficence, and justice. The author presents sensitive approaches for culturally diverse groups in health care areas and cautions against dichotomy in cross-cultural studies, which ignores the dynamic nature and intravariations of cultures. As a way of health care providers to become engaged in cultural diversity in nursing practice and research, the author suggests that they do not only have a general knowledge about the theoretical differences among groups through "normative analysis" but also learn to appreciate each individual's particular beliefs and values through narratives of morality. Health care providers as well as legal professionals need to cultivate "cultural humility," which is the willingness to explore the similarities and differences between their own and each client's priorities and values and to develop courses of action with patients.     

Disqualified Bodies: A Sociolegal Analysis of the Organ Trade in Cairo,Egypt

Legislative and policy interventions in response to the organ trade have centered on the introduction of criminal sanctions in an effort to deter organ sales and/or “trafficking.” Yet, such measures fail to take account of the social and political processes that facilitate the exploitation of individuals in organ markets in different contexts. Informed by empirical data, gathered via a series of in‐depth interviews with Sudanese migrants who have sold a kidney, this paper examines the link between increased urbanization, migration patterns, informalization, and the emergence of organ markets in the Egyptian‐Sudanese context. The findings illustrate how processes of legal marginalization and social exclusion leave people vulnerable to exploitation in organ markets. The prevailing law enforcement response does not capture or respond to the empirical reality. Accordingly, this paper shifts the emphasis away from criminalization toward an analysis of the legal barriers and policy decisions that shape the poor bargaining position of organ sellers. In doing so, it opens up discussion of the organ trade onto wider critiques that disrupt boundaries between formality and informality in labor markets and trouble dominant modes of criminalization.