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Catch Us If You Can!!! is the improbable nameof an Italian weblog managed by Lorenzo Litta and mastermindedby veteran IP expert Stefano Sandri. Although it is rarely possibleto measure what a blog achieves, it is usually quite feasibleto identify what it tries to do. In this instance the bloggersobjective is to raise their readers sensitivity towardsintellectual property rights issues and to create a greaterawareness of the parameters of protection and permitted usein a culture which places a 相似文献
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Veni, vidi, vici! (I came, I saw, I conquered),Julius Caesar's memorable soundbite from the Battle of Zelain 47 BC, has been for nearly two millennia a byword for thetriumph of the new order over the old. Substitute the homophonewiki for vici and the symbolismremains apt. While the rise of the personal computer, the developmentof the internet and the advent of mobile telephony have eachbeen hailed as the greatest transformative feature 相似文献
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Not many films have as overt an intellectual property themeas the Oscar-nominated The Man in the White Suit, a sweet-and-sourEaling comedy with compelling social content. The protagonist,Sidney Stratton (played by Sir Alec 相似文献
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Base rates for malingering are often obtained and averaged across multiple clinicians who apply heterogeneous methods for detection (Mittenberg et al., J Clin Exp Neuropsychol 24: 1094?1102, 2002; Young, Psychol Inj Law 8: 200–218, 2015). Our aims of obtaining homogenous base rates included the following: (a) evaluation of all our legal cases in accordance with the guidelines set forth in the position papers by both the National Academy of Neuropsychology and the Association for Psychological Advancement in Psychological Injury and Law, (b) minimal variation between our comprehensive neuropsychological examinations, and (c) determination of base rates of failed effort in 150 consecutively examined legal cases in one medical setting. To assess the various levels of volitional exaggeration, we introduced four gradations of poor effort definitions, which relied on performance validity tests (PVTs). A comparison between two consecutive samples of 75 litigants indicated less frequent poor effort with increasingly more conservative criteria. In our analysis of a subset of litigants who sustained traumatic brain injuries (N?=?115), the four base rates for mild versus moderate-severe TBI groups were equivalent for the two more lenient malingering definitions but varied for the two more conservative definitions. Specifically, for the mild TBI cases investigated, the percentage of three PVT failures (or one PVT failure significantly below chance) arrived at 3.4 %. Our final aim was to compare the base rates of poor effort that were obtained with PVTs to the base rates of emotional and physical symptom endorsement, which were obtained with symptom validity tests (SVTs). No significant correlations emerged in this analysis. The discussion emphasizes the relatively lower base rates of poor effort found in the convenience sample studied in neuropsychological evaluations relative to the higher estimates in the literature (40 +/? 10 %, Larrabee et al., Clin Neuropsychol 23: 841–849, 2009) but not others based on comprehensive review (Young, Psychol Inj Law 8: 200–218, 2015). 相似文献
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Dan Nana Osei Bonsu PhD Denice Higgins PhD Claire Simon BSc Corey S. Goodwin PhD Julianne M. Henry PhD Jeremy J. Austin PhD 《Journal of forensic sciences》2023,68(4):1302-1309
Metals can pose challenges while conducting forensic DNA analysis. The presence of metal ions in evidence-related DNA extracts can degrade DNA or inhibit PCR as applied to DNA quantification (real-time PCR or qPCR) and/or STR amplification, leading to low success in STR profiling. Different metal ions were spiked into 0.2 and 0.5 ng of human genomic DNA in an “inhibition study” and the impact was evaluated by qPCR using the Quantifiler™ Trio DNA Quantification Kit (Thermo Fisher Scientific) and an in-house SYBR Green assay. This study reports on a contradictory finding specific to tin (Sn) ions, which caused at least a 38,000-fold overestimation of DNA concentration when utilizing Quantifiler Trio. This was explained by the raw and multicomponent spectral plots, which indicated that Sn suppresses the Quantifiler Trio passive reference dye (Mustang Purple™, MP) at ion concentrations above 0.1 mM. This effect was not observed when DNA was quantified using SYBR Green with ROX™ as the passive reference, nor when DNA was extracted and purified prior to Quantifiler Trio. The results show that metal contaminants can interfere with qPCR-based DNA quantification in unexpected ways and may be assay dependent. The results also highlight the importance of qPCR as a quality check to determine steps for sample cleanup prior to STR amplification that may be similarly impacted by metal ions. Forensic workflows should recognize the risk of inaccurate DNA quantification of samples that are collected from substrates containing tin. 相似文献
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Abnormal Daily Temperature and Concern about Climate Change Across the United States 总被引:1,自引:0,他引:1
The relatively low level of concern about climate change among Americans has important implications for climate policy. While many studies have examined individual characteristics associated with climate change attitudes, fewer studies have considered the effects of environmental conditions on such attitudes. Here, we use two national samples of American adults to explore the impact of abnormal daily temperatures on levels of concern about climate change. We test the hypotheses that (1) abnormally warm temperatures, and (2) both abnormally warm and abnormally cool temperatures are associated with higher levels of concern. Using a generalized ordinal logit, we find that the quadratic form of deviation from mean temperature on the date of the survey is significantly associated with higher levels of concern, thus supporting the second hypothesis. We discuss several theoretical frameworks that may explain this result including availability bias, mental models, and implicit stimuli, and the implications for climate policy. 相似文献