Age calculation using X-ray microfocus computed tomographical scanning of teeth: a pilot study

To correlate dental age with an individual's chronological age based on the calculated volume ratio of pulp versus tooth volume measured, an X-ray microfocus computed tomography unit (microCT) with 25 microm spatial resolution was used to non-destructively scan 43 extracted single root teeth of 25 individuals with well-known chronological age. Custom-made analysis software was used by two examiners to obtain numerical values for pulpal and tooth volume. The ratio of both was calculated and statistically processed. No significant intra- or inter-examiner differences were found. In fact, a very strong concordance correlation coefficient was found. Linear regression analysis showed a coefficient of determination (r) of 0.31 which suggests that there is a rather weak correlation between the volume ratio of pulp versus tooth and biological age. Although rather time consuming, this technique shows promising results for dental age estimation in a non-destructive manner using X-ray microfocus computed tomography.     

Multi-sector cooperation in preventing crime: the case of a South African Neighbourhood Watch as an effective crime prevention model

Abstract

This case study describes the experience of effective and sustainable multi-sector co-operation in the prevention of crime between the Roodekrans Neighbourhood Watch (RNW) in Roodepoort, South Africa, the South African Police Service, private security businesses and the local business sector. This case study is illustrated in the context of empowering communities to take ownership of community safety by facilitating a multi-sector approach. Many studies have highlighted the role of the police in driving crime prevention, however, this paper focuses on the role and contribution of communities themselves as an effective vehicle of crime prevention drawing on multi-sector co-operation. Knowledge regarding best practices in this field of crime prevention remains a work in progress, therefore this paper aims to contribute to the general framework for the growth of successful multi-sector community-based crime prevention initiatives.     

Developments in pharmacists' disciplinary processes and outcomes

Pharmacy disciplinary processes and outcomes protect consumers by deterring pharmacists from unacceptable practices and maintaining the reputation and standing of the pharmacy profession. It is important that pharmacists are informed of disciplinary processes and outcomes in order to predict what is regarded as unacceptable behaviour and the potential consequences thereof. Disciplinary procedures and outcomes also play an important role in maintaining public trust in the pharmacy profession and it is therefore important that the public has confidence in the disciplinary structure. The outcomes of pharmacy disciplinary cases that reflect the patient care role of pharmacists are particularly important in helping to determine pharmacists' changed professional responsibility and potential legal liability in the provision of these patient care services.     

Respect for Persons in Bioethics: Towards a Human Rights-Based Account

Human rights have increasingly been put forward as an important framework for bioethics. In this paper, it is argued that human rights offer a potentially fruitful approach to understanding the notion of Respect for Persons in bioethics. The idea that we are owed a certain kind of respect as persons is relatively common, but also quite often understood in terms of respecting people’s autonomous choices. Such accounts do however risk being too narrow, reducing some human beings to a second-class moral status. This paper puts forward a political approach to our standing as persons and a strongly pluralistic account of human rights that lays the ground for a more broadly applicable conception of Respect for Persons. It is further argued that this model also provides an example of a more general approach to philosophical ethics, an approach which is here called taxonomical pluralism. When it comes to Respect for Persons specifically, this principle is developed in terms of five distinct core concerns (autonomy, dignity, integrity, privacy, and vulnerability).     

Bad neighbors? How co-located Chinese and World Bank development projects impact local corruption in Tanzania

The rise of China as a "non-traditional" development partner has been one of the most important phenomena in the field over the past decade. The lack of transparency in Chinese development projects, coupled with an uninterested stance towards governance, lead many to wonder if Chinese engagement will contribute to or undermine existing development efforts. This paper adds to the debate by inquiring as to the relationship of Chinese development efforts with perceptions of, and experiences with, corruption when projects are closely-located to those from a traditional donor, the World Bank. Taking advantage of spatial data, the paper evidences an association between the location of a larger number of Chinese projects and higher experiences with and, to some extent, perceptions of corruption when accounting for co-located World Bank projects. Likewise, while World Bank projects are associated with lower levels of corruption in the absence of Chinese projects, this relationship disappears when Chinese projects are nearby. However, these relationships only hold for Chinese projects which are not "aid-like," suggesting that the differentiation of Chinese overseas flows is an important consideration when studying China as a development partner.     

The Invisible Hand? Critical Information Infrastructures,Commercialisation and National Security

Corporatisation of critical information infrastructure (CII) is rooted in the ‘privatisation wave’ of the 1980s-90s, when the ground was laid for outsourcing public utilities. Despite well-known risks relating to reliability, resilience, and accountability, commitment to efficiency imperatives have driven governments to outsource key public services and infrastructures. A recent illustrative case with enormous implications is the 2017 Swedish ICT scandal, where outsourcing of CII caused major security breaches. With the transfer of the Swedish Transport Agency’s ICT system to IBM and subcontractors, classified data and protected identities were made accessible to non-vetted foreign private employees – sensitive data could thus now be in anyone’s hands. This case clearly demonstrates accountability gaps that can arise in public-private governance of CII.     

Development of a harmonised method for the profiling of amphetamines: III. Development of the gas chromatographic method

This study focused on gas chromatographic analysis of target compounds found in illicit amphetamine synthesised by the Leuckart reaction, reductive amination of benzyl methyl ketone, and the nitrostyrene route. The analytical method was investigated and optimised with respect to introduction of amphetamine samples into the gas chromatograph and separation and detection of the target substances. Sample introduction using split and splitless injection was tested at different injector temperatures, and their ability to transfer the target compounds to the GC column was evaluated using cold on column injection as a reference. Taking the results from both techniques into consideration a temperature of 250 degrees C was considered to be the best compromise. The most efficient separation was achieved with a DB-35MS capillary column (35% diphenyl 65% dimethyl silicone; 30 m x 0.25 mm, d(f) 0.25 microm) and an oven temperature program that started at 90 degrees C (1 min) and was increased by 8 degrees C/min to 300 degrees C (10 min). Reproducibility, repeatability, linearity, and limits of determination for the flame ionisation detector (FID), nitrogen phosphorous detector (NPD), and mass spectrometry (MS) in scan mode and selected ion monitoring (SIM) mode were evaluated. In addition, selectivity was studied applying FID and MS in both scan and SIM mode. It was found that reproducibility, repeatability, and limits of determination were similar for FID, NPD, and MS in scan mode. Moreover, the linearity was better when applying FID or NPD whereas the selectivity was better when utilising the MS. Finally, the introduction of target compounds to the GC column when applying injection volumes of 0.2 microl, 1 microl, 2 microl, and 4 microl with splitless injection respectively 1 microl with split injection (split ratio, 1:40) were compared. It was demonstrated that splitless injections of 1 microl, 2 microl, and 4 microl could be employed in the developed method, while split injection and splitless injections of 0.2 microl should be avoided.