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In this study of 212 unrelated Singapore Chinese males, allelic frequencies and gene diversities of 11 Y-chromosome specific STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS438 and DYS439) were established. A total of 184 haplotypes were observed in the 212 individuals studied, of which 165 (89.67%) were unique. The most common haplotype was observed in five (2.35%) individuals. The overall haplotype diversity for the 11 Y-STR loci was 99.81%, and the discrimination capacity was 86.79%.  相似文献   
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Two probabilistic genotyping (PG) programs, STRMix™ and TrueAllele™, were used to assess the strength of the same item of DNA evidence in a federal criminal case, with strikingly different results. For STRMix, the reported likelihood ratio in favor of the non-contributor hypothesis was 24; for TrueAllele it ranged from 1.2 million to 16.7 million, depending on the reference population. This case report seeks to explain why the two programs produced different results and to consider what the difference tells us about the reliability and trustworthiness of these programs. It uses a locus-by-locus breakdown to trace the differing results to subtle differences in modeling parameters and methods, analytic thresholds, and mixture ratios, as well as TrueAllele's use of an ad hoc procedure for assigning LRs at some loci. These findings illustrate the extent to which PG analysis rests on a lattice of contestable assumptions, highlighting the importance of rigorous validation of PG programs using known-source test samples that closely replicate the characteristics of evidentiary samples. The article also points out misleading aspects of the way STRMix and TrueAllele results are routinely presented in reports and testimony and calls for clarification of forensic reporting standards to address those problems.  相似文献   
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This brief Editorial reflects on 14th July 2014, the day when at long last the General Synod of the Church of England voted to allow women to become bishops. It has taken at least a century of campaigning, particularly by determined women, for this to happen.  相似文献   
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This appreciation remembers the life of Jo Cox, a British Member of Parliament (MP), who was brutally murdered on 16 June 2016. A Labour Party feminist, Jo campaigned for women’s rights around the world. After graduating from the University of Cambridge in 1995, she became a political adviser for various MPs and then worked for Oxfam, the Maternity Mortality Campaign, Save the Children and the National Society for the Protection of Cruelty to Children. Jo Cox wanted to make the world a better place, a place of justice and peace.  相似文献   
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Abstract

Ben Shaw, mechanic of Preston, Lancashire, began to write his family history in 1826. It describes the disruptions caused by industrialization and migration to Ben and Betty Shaw and their extended families. This article reflects upon the domestic economies Shaw describes and sees these households as key institutions for mutually organised survival and betterment and as the focus for the diverse activities of women's work. Households were linked into wider support networks between kin and neighbours. Reciprocity was rarely calculative. Gendered power relations could also be close affective relations, despite conflict. Women were vital to this bargain between care and resources which, for this family at least, helped negotiate the contradictions in social identities shaped by both gender and class across the public/private divide  相似文献   
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This essay, based on a presentation at the 2009 Future of Family Law Education conference at the William Mitchell School of Law, discusses strategies for teaching controversial topics, focused on reproductive rights and related gender issues.  相似文献   
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