The Effects of Gastroesophageal Reflux Disease on Forensic Breath Alcohol Testing

Fifteen test subjects, 10 of whom were diagnosed with gastroesophageal reflux disease (GERD), were dosed with alcohol to BACs above 0.150 g/dL. Blood and breath assays taken at 20-min intervals for 8 h after dosing demonstrated close agreement between postabsorptive BAC and BrAC values. Three subjects exhibited elevated breath alcohol concentrations up to 0.105 g/dL during the absorptive phase that were apparently due to the passage of gastric alcohol through the lower esophageal sphincter not attributable to eruction or regurgitation. The effect of gastric alcohol was not consistently proportional to the amount of unabsorbed gastric alcohol. Absorption of alcohol in the esophagus explains the nonproportionality. Breath samples contaminated by GERD-related alcohol leakage from the stomach into a breath sample were found only when there was a high concentration of alcohol in the stomach. When contaminated breath samples were encountered, they were irreproducible in magnitude.     

A Pilot Study Examining the Reduction of Trauma Symptomatology in Families to Prevent Child Abuse And Neglect: Trauma Adapted Family Connections

This article presents the preliminary outcomes of a 6-month, in-home trauma-adapted neglect prevention program intended to reduce trauma-related risk factors in families and increase caregiver, child, and family well-being. Standardized measures were administered via a computer assisted self-interview (CASI) at intake and case closure. At the time of the analyses 72 caregivers and 105 children completed both an intake and closing CASI. Significant differences were found over time in the reduction of caregiver and child related post-traumatic stress (PTS) symptomatology. Outcomes in overall caregiver, child, and family well-being and safety significantly improved over time. Evidence suggests that trauma adaptation of the empirically supported neglect prevention program shows great promise in filling a service gap and in helping families who are chronically traumatized and struggling to meet their children's basic needs.     

Garden of Grand Vision: Economic life in a flophouse complex Harbin, China 1940

During the Second World War Harbin was a major city in the puppet-state ofManzhouguo, the industrial heart of the Japanese war effort in East Asia.The Garden of Grand Vision was a flophouse complex located in the Chineseslums of Harbin. The 2,000 drug addicts, gamblers and prostitutes who madethe Garden their home were mostly migrants from North China who had fallenon hard times. In 1940 the Japanese police conducted a detailed survey oflife in the Garden, portraying it as a swamp of disorder and immorality.In contrast, this paper describes the residents of the Garden as theyvaliantly participated in a vigorous underground economy and arranged theirlives for survival.     

Assessing legal change: Recidivism and administrative per se laws

Tougher sanctions for drunk driving have often been advocated as a means to reduce this problematic behavior. In a test of administrative per se laws as a specific deterrent, the impact of introducing such laws is evaluated by examining reconviction rates of offenders before and after implementation of the Jaw in three states (North Dakota, Louisiana, and Mississippi), with comparisons made to a fourth state during the same time period that did not implement an administrative per se law (California). Recidivism is analyzed using survival models. The results indicate that administrative per se laws reduce rates of reconviction in some situations but not in others. In particular, if implementation of the law is accompanied by changes in overall rates of license actions, the specific deterrent effects of the law may be outweighed by the increased efficiencies of this judicial process.     

Traumatic Events and Maternal Education as Predictors of Verbal Ability for Preschool Children Exposed to Intimate Partner Violence (IPV)

Despite research on the effects of intimate partner violence (IPV) on children, little is known about its impact on cognitive development. In this study, 87 preschool-aged children and their mothers exposed to IPV within the last two years participated in interviews to ascertain verbal ability, history of violence, and exposure to trauma. When compared to a national sample of 1,700 same-age children not evaluated for exposure to traumatic events, children exposed to IPV scored significantly lower on verbal ability, as assessed with standardized measures. In order to understand variation in verbal ability, multiple regression models were tested. Both prior exposure to traumatic events and the level of mother’s education were significant predictors of verbal ability. However, level of education mediated the relationship between traumatic events and the child’s verbal ability.     

Development of a DNA-based macroarray for the detection and identification of Amanita species

A DNA-based macroarray was designed to quickly and accurately identify certain Amanita mushroom specimens at the species level. The macroarray included probes for Amanita phalloides and Amanita ocreata, toxic species responsible for most mushroom poisonings, and Amanita lanei and Amanita velosa, edible species sometimes confused with toxic species, based on sequences of the highly variable internal transcribed spacer (ITS) region of rDNA. A cryptic species related to A. ocreata and one related to A. lanei, identifiable by ITS sequences, were also included. Specific multiple oligonucleotide probes were spotted onto nylon membranes and the optimal hybridization temperatures were determined. The Amanita DNA array was highly specific, sensitive (0.5 ng DNA/μL and higher were detected), and reproducible. In two case studies, the method proved useful when only small amounts of mushroom tissue remained after a suspected poisoning. An identification could be completed in 12 h.