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71.
Saliva or "oral fluid" has been presented as an alternative matrix to document drug use. The non-invasive collection of a saliva sample, which is relatively easy to perform and can be achieved under close supervision, is one of the most important benefits in a driving under the influence situation. Moreover, the presence of Delta9-tetrahydrocannabinol (THC) in oral fluid is a better indication of recent use than when 11-nor-Delta9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) is detected in urine, so there is a higher probability that the subject is experiencing pharmacological effects at the time of sampling. In the first part of the study, 27 drug addicts were tested for the presence of THC using the OraLine IV s.a.t. device to establish the potential of this new on-site DOA detection technique. In parallel, oral fluid was collected with the Intercept DOA Oral Specimen Collection device and tested for THC by gas chromatography mass spectrometry (GC/MS) after methylation for THC (limit of quantification: 1 ng/mL). The OraLine device correctly identified nine saliva specimens positive for cannabis with THC concentrations ranging from 3 to 265 ng/mL, but remained negative in four other samples where low THC concentrations were detected by GC/MS (1-13 ng/mL). One false positive was noted. Secondly, two male subjects were screened in saliva using the OraLine and Intercept devices after consumption of a single cannabis cigarette containing 25mg of THC. Saliva was first tested with the OraLine device and then collected with the Intercept device for GC/MS confirmation. In one subject, the OraLine on-site test was positive for THC for 2 h following drug intake with THC concentrations decreasing from 196 to 16 ng/mL, while the test remained positive for 1.5 h for the second subject (THC concentrations ranging from 199 to 11 ng/mL). These preliminary results obtained with the OraLine IV s.a.t. device indicate more encouraging data for the detection of THC using on-site tests than previous evaluations. 相似文献
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Regulation of the Global Marketplace for the Sake of Health 总被引:1,自引:0,他引:1
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Marion Pines 《政策研究评论》1987,6(4):782-788
To maximize the use of human capital, employment and training resources need to be redirected to meet four objectives: (1) reduce welfare dependency by helping people gain skills for self-sufficiency, (2) prepare a new workforce through better education of youth, (3) retrain dislocated workers, and (4) develop an employment system that links workers and jobs through the coordination of institutions. Suggestions for federal, state, and local initiatives to meet these objectives are spelled out. Particular emphasis is placed upon both a significant revitalization of the federal role in employment and training and a reassessment of traditional approaches. 相似文献
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The effectiveness of social skills training (SST) for juvenile delinquents: a meta-analytical review
van der Stouwe Trudy Gubbels Jeanne Castenmiller Yvonne L. van der Zouwen Marion Asscher Jessica J. Hoeve Machteld van der Laan Peter H. Stams Geert Jan J. M. 《Journal of Experimental Criminology》2021,17(3):369-396
Journal of Experimental Criminology - To examine the effectiveness of social skills training (SST) for juvenile offenders and for whom and under which conditions SSTs are the most effective.... 相似文献
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Matan Farhi DMD MS Natalie Tomas DDS MS Ian Marion DDS MS David Avenetti DDS MSD MPH Phimon Atsawasuwan DDS MS PhD Marcio da Fonseca DDS MS Mustafa Al Atabbe BS Christina L. Nicholas PhD 《Journal of forensic sciences》2023,68(1):242-251
Human remains from forensic and bioarcheological contexts are often fragmentary, requiring methods for estimating a forensic profile that are based upon limited skeletal features. In 2017, Berg and Keryhercz created an online application, (hu)MANid, that provides sex and ancestry estimation from mandibular morphoscopic traits and linear measurements. In this study, we examine the utility of the (hu)MANid application in a diverse, urban US adult sample (aged 20–45; n = 143) derived from computed tomography (CT) scans. We secondarily conduct a preliminary analysis of the program's utility in a sample of adolescents (aged 15–17; n = 40). Six morphoscopic, and eleven morphometric traits were recorded as directed by the literature associated with the (hu)MANid program. Percent correct classification and posterior predictive values were calculated for the sex and ancestry estimations output by the program; chi-squared tests were employed to compare self-reported and predicted ancestry. In the adult sample, sex was accurately predicted for 75.52% of the sample. Ancestry prediction, however, was less favorable ranging from 19.3% to 50% correct. For the adolescent sample, correct sex estimation (45%) did not surpass what could occur by chance alone, though ancestry prediction fared better than in the larger adult sample (percent correct prediction overall average: 47.5%, range 35.71%–71.43%). The (hu)MANid application shows utility for use with CT scan-derived adult samples for sex estimation, but caution is warranted for ancestry estimation and use with samples that may not have reached full adult maturity. 相似文献