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91.
Darrell O. Ricke Ph.D. Philip Fremont‐Smith M.S. James Watkins B.S. Sara Stankiewicz M.S. Tara Boettcher B.S. Eric Schwoebel Ph.D. 《Journal of forensic sciences》2019,64(5):1468-1474
High‐throughput sequencing (HTS) of large panels of single nucleotide polymorphisms (SNPs) provides an alternative or complimentary approach to short tandem repeats (STRs) panels for the analysis of complex DNA mixture forensic samples. For STRs, methods to estimate individual contribution concentrations compare capillary electrophoresis peak heights, peak areas, or HTS allele read counts within a mixture. This article introduces three approaches (mean, median, and slope methods) for estimating individual DNA contributions to forensic mixtures for HTS/massively parallel sequencing (MPS) SNP panels. For SNPs, the major:minor allele ratios or counts, unique to each contributor, were compared to estimate contributor proportion within the mixture using the mean, median, and slope intercept for these alleles. The estimates for these three methods were typically within 5% of planned experimental contributions for defined mixtures. 相似文献
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Abstract The development of a joint US-Japan theater missile defense system could have significant ramifications beyond the defense of Japan and of American forces in the region. A growing debate within Japan on its international security position, the spread of weapons of mass destruction, and questions about the role of the United States in the region conspire to create conditions for significant changes in Japan's conception of its security status and its long‐term political-military calculations. By upgrading Japan's strategic responsibilities, theater missile defense could inadvertently induce a reassessment of many of its national security policies, perhaps even the decision to forego nuclear weapons. 相似文献
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Mark Harrison 《The Journal of peasant studies》2013,40(4):323-336
Is there a peasant mode of production? Chayanov's work can be construed as a theory of the peasant mode of production at the level of the labour process. This labour process is analysed in terms of the forces of production, the relationship between the peasant and the means of production, and that between the peasant and the product. When subjected to an historical critique, from the point of view of the formation and decomposition of the peasantry, Chayanov's theory of a peasant mode of production yields to the idea of peasantry as a specific combination of structures. 相似文献
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R. E. F. Smith 《The Journal of peasant studies》2013,40(4):489-490
Eric Hobsbawm's outline of the concept of social banditry suggest certain conditions of existence for that mode of primitive rebellion. Primary among these conditions are the presence of a ‘traditional peasant environment and the absence of ‘industrial capitalism’. This paper presents a critique of Hobsbawm's specifications, and suggest two alternative conditions: the presence of class conflict which unites direct producers, and the absence of effective, institutionalised political organisation of producers’ interests. This reformulation is illustrated by reference to the Kelly Outbreak in late nineteenth century Australia. 相似文献