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301.
Pasquale-Styles MA Sochaski MA Dorman DC Krell WS Shah AK Schmidt CJ 《Journal of forensic sciences》2006,51(5):1154-1157
Bromethalin is a neurotoxin found in some rodenticides. A delusional 21-year-old male presented to a hospital with altered mental status the day after ingesting a bromethalin-based rodenticide. He died 7 days after his self-reported exposure to c. 17 mg bromethalin (equivalent to 0.33 mg bromethalin/kg). His clinicopathologic course was characterized by altered mental status, obtundation, increased cerebrospinal fluid pressure, cerebral edema, death, and diffuse histologic vacuolization of the white matter in the central nervous system seen on microscopic examination at autopsy. The presence of a demethylated form of bromethalin in the patient's liver and brain was confirmed by gas chromatography with mass spectrometry. Clinical signs and lesions observed in this patient are similar to those seen in animals poisoned with bromethalin. This case illustrates the potential for bromethalin ingestion to result in fatal human poisoning. 相似文献
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Ritz-Timme S Thome M Grütters G Grütters M Reichelt JA Bilzer N Kaatsch HJ 《Forensic science international》2006,156(1):16-22
The purpose of this study was to specify the effects of alcohol on the performance of ship operators as a contribution to the development of new strategies against the risks of alcohol in water traffic. The nautical performance of 21 captains before and after alcohol consumption was assessed on a ship piloting simulator. The simulated scenarios represented passages of a container vessel through the German Bight. Performance was examined by nautical instructors according to standardised protocols. Mean (S.D.) blood alcohol concentrations (BACs) of 0.100 (0.024) g/dl before and 0.100 (0.017) g/dl after the performance trial resulted in striking effects on the nautical performance. The categories most severely affected were foresight and analysis of situation (impairment in 18 of 21 cases), concentration (impairment in 16 of 21 cases), accurateness, risk disposition and navigation (impairment in 15 of 21 cases). Chart work, preparation and communication were impaired in 12, 11 and 10 of 21 cases, respectively. None of the participants were capable to operate the simulated ship with an adequate safety after ingestion of alcohol. From these findings, and in consideration of the well-established impairment of a multitude of mental and physical functions by alcohol, it can be concluded that even low BACs bear high risks in water traffic, a concentration above 0.1 g/dl will hinder a sufficiently safe performance of ship operators. This should be considered in alcohol education and legislation. 相似文献
304.
Mark N. Franklin 《Electoral Studies》1982,1(2):195-220
The weakening of the British class alignment since the early 1960s has been extensively documented in past research. This article seeks to identify components contributing to the extent of class alignment, so as to clarify what is that has declined, and when; and to speculate about the reasons for the decline and its implications for the future of the British party system. In fact only one component shows any systematic change over a fifteen year period, and this change can be placed quite specifically between 1966 and 1970. Several more recent events in British politics appear to have causes that can be traced to this original change. 相似文献
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Donald R. Kinder Mark D. Peters Robert P. Abelson Susan T. Fiske 《Political Behavior》1980,2(4):315-337
The American public expresses considerable consensus on those qualities of character and performance indispensable to a modern president. Contrary to expectations, however, such conceptions of an ideal president (or presidential prototypes) generally failed to provide standards by which actual presidential candidates were evaluated. Across five complementary tests, qualities that citizens thought important for an ideal president counted no more heavily in their evaluations of presidential hopefuls than did qualities thought less important—with one consistent and striking exception. Conceptions of an ideal president did set the standards by which the incumbent president was evaluated, and quite powerfully so. In the final section of the paper, we provide several interpretations of these results, suggest how public conceptions of an ideal president are acquired, and speculate about processes of presidential appraisal. 相似文献
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