Evaluation of Degradation in DNA from Males with a Quantitative Gender Typing,Endpoint PCR Multiplex

Evidentiary samples submitted to a forensic DNA laboratory occasionally yield DNA that is degraded. Samples of intact chromosomal DNA (both nuclear and mitochondrial) were subjected to a heating protocol to induce DNA degradation. The DNAs were then analyzed using a multiplex PCR assay that amplifies targets of low and high molecular weight on the X/Y and mitochondrial chromosomes. If degradation is random, the amplification of larger DNA targets should be more adversely affected by degradation than smaller targets. In nuclear and mitochondrial DNA from a male donor, exhibiting degradation, DNA quantity estimates based upon higher molecular weight amplicons (HMW) are significantly lower than estimates made using low molecular weight (LMW) Q‐TAT amplicons. DNA degradation estimated using this approach correlated well with actual fluorescence associated with HMW and LMW STR alleles amplified from the same genomic DNA templates. Q‐TAT is thus useful not only as a quantitation tool, but also as an indicator of template degradation.     

Physical restraint and the therapeutic relationship

The role of the forensic mental health nurse has led to many debates due to the conflicts between security and therapeutic aspects of their role. Physical restraint is a security element of the role which may have an impact on their ability to work therapeutically with patients. This study examined the impact of physical restraint on the nursing staff–patient therapeutic relationship. This was investigated in a secure unit in the North of England. Eight semi-structured interviews were conducted with patients across the service, and thematic analysis was undertaken. Five themes were identified from the data which highlighted the impact of the physical restraint as a power imbalance, the experience as traumatic, the importance of justification, the negative attributes and motives of some staff and the impact of coping with powerlessness. Clinical implications and research recommendations are discussed further in this article.     

Beyond (and Within) City Limits: Climate Policy in an Intergovernmental System

This analysis explores the role of city‐level and state‐level variables to explain why some cities make more progress on climate‐related policy implementation than others. Using multilevel modeling, we find little support for the influence of state factors on local government leadership among the 812 cities in the dataset, but local government institutional and community variables are strongly associated with climate policy initiatives. We argue for a rethinking of the notion of the limited and constrained city and suggest that, in the realm of climate protection and environmental policy, cities are leading a bottom‐up federalism. Moreover, where some political analysts and scholars have argued that climate protection and environmental policies may not be economically rational for cities to pursue, we theorize that cities are acting locally to further their self‐interest in an increasingly global economy.     

Citizenship without states: rehabilitating citizenship discourse among the anarchist left

The purpose of this paper is threefold. First, it seeks to give expression to the trends of an important debate that has not been formally articulated among anarchist theorists, namely whether or not the concept ‘citizenship’ can be meaningfully salvaged and repurposed. While many anarchist theorists have gestured at such a debate, the dimensions of this discourse have not been clarified. Secondly, in identifying the features of this debate, this paper seeks to show that citizenship can be meaningfully rehabilitated by the anarchist left. And finally, this essay seeks to provide some preliminary reasons why anarchist theories of citizenship may provide a fruitful partnership with theorists of citizenship today, especially those engaging in critical citizenship studies.     

On the “Exporting” of Morality: Its Relation to Political Conservatism and Epistemic Motivation

A new phenomenon, moral exporting (ME), is introduced to capture active attempts to promote certain views of morality to others. It was hypothesized that political conservatives would be more likely to exhibit ME, due in part to strong epistemic concerns for certainty that may become attached to the moral domain. Related items from the 1988 and 2006 General Social Surveys were analyzed, and new scales were developed to better assess ME and specific moral-related epistemic concerns (moral absolutism). In a second study, these scales were administered to a large college student sample along with measures of political ideology and need for closure (NFC). Results generally showed that political conservatism was strongly related to the new ME factor. Further analysis determined that both moral absolutism (MA) and NFC accounted for significant portions of this relationship, but that the specific epistemic construct (MA) was a more proximal mediator. Discussion centers on further distinguishing ME and MA from related constructs, as well as on future research and applications.     

How the WTO Matters to Industry: The Case of Scotch Whisky

Although the World Trade Organization (WTO) has spawned a considerable academic literature, as yet research on this organization has rarely been problematized around clear theories of the relationship between law, economics, and politics. Building upon institutionalist premises and concepts drawn from political sociology and industrial economics, this article suggests a means of filling this gap by grasping the "political work" involved in the regulation of specific industries. Illustrated through the case of Scotch whisky, a focus is developed on how the WTO matters to contemporary industry. This reveals that the most powerful actors in industries such as Scotch have developed resources which legitimize their simultaneous engagement in a range of decision-making arenas. These include, but are not necessarily dominated by, the WTO.     

Political Communication in the UK: A Study of Pressure Group Behaviour

The main political parties' adoption of 'soundbites' and 'spin-doctors' has led UK political communication to become dominated by a 'promotional culture'. This article describes the historical development of this trend and the academic debate it has stimulated over the 'quality' of contemporary political communication. The article then argues that by exploring how pressure groups have adopted similar promotional techniques a valuable new dimension can be added to this debate, which focuses on the ability to gain access to media coverage. Finally, this point is illustrated with a case study of Liberty, a civil liberties pressure group.     

Institutionalising the 'eternal return': textbooks and the study of British politics

Anthony Birch, The British System of Government
Ian Budge and David McKay (eds), The Developing British PoliticalSystem: the 1990s
Ian Budge, Ivor Crewe, David McKay and Ken Newton, The NewBritish Politics
Bill Coxall and Lynton Robins, Contemporary British Politics
John Dearlove and Peter Saunders, Introduction to British Politics
Patrick Dunleavy, Andrew Gamble, Ian Holliday and Gillian Peele (eds), Developments in British Politics 5
Bill Jones, Andrew Gray, Dennis Kavanagh, Michael Moran, Philip Nortonand Anthony Seldon, Politics UK
Dennis Kavanagh, British Politics: Continuities and Change
John Kingdom, Government and Politics in Britain: An Introduction
John P. Mackintosh, The Government and Politics of Britain
R. M. Punnett, British Government and Politics
Robert Pyper and Lyton Robins (eds), Governing the UK in the 1990s