Studies on the stability and detection of cocaine, benzoylecgonine, and 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid in whole blood using Abuscreen radioimmunoassay

A study was undertaken to assess the stability and the radioimmunoassay (RIA) detection of cocaine, benzoylecgonine (BZE), and 11-nor-delta-9-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) in whole blood while stored in 4 different kinds of blood collection tubes for up to 30 days at refrigeration and room temperatures. At various intervals, the tubes were sampled and analyzed using Abuscreen RIA. Also, semi-quantitative data derived from RIA analysis of forensic blood specimens were compared with quantitative data acquired using gas chromatography (GC) or GC/mass spectrometry (GC/MS) on the same specimens. RIA and chromatographic studies revealed that BZE and THC-COOH were stable in blood under all conditions studied. Cocaine, however, was found not to be stable in blood, especially when stored at room temperatures. Despite cocaine's instability in blood, RIA was able to detect the presence of cocaine and its breakdown products in blood under all conditions studied.     

State Constitutional Limits on Legislative Procedure: Legislative Compliance and Judicial Enforcement

Most state constitutions contain detailed restrictions on thelegislative process. Violations of some of these restrictions(e.g., single-subject requirements) are reflected on the faceof a final enactment. Other violations (e.g., alteration ofa bill to change its original purpose) are not evident in thefinal enactment, but require investigation of the legislativeprocess. State courts have developed a variety of approachesto these second types of violations, from excluding all evidencebeyond the enactment to permitting any evidence of constitutionalviolations. The Pennsylvania Abortion Control Act was passedin apparent violation of both types of constitutional restrictions.The legislative debates reflected legislators' attitudes aboutsuch restrictions, but the Pennsylvania courts refuse to enforcethem. After surveying other judicial approaches, the articlediscusses the legislative and executive obligation to followconstitutional restrictions, regardless of judicial enforcement.The article then advocates increased judicial enforcement, whilemaintaining proper deference to the legislature.     

Book Reviews

Michael Graham Fry (ed.), Power, Personalities and Politics: Essays in Honour of Donald Cameron Watt (London: Frank Cass 1992) £35. ISBN 0 7146 3428 X.

John L. Offner, An Unwanted War: The Diplomacy of the United States and Spain over Cuba, 1895-1898 (Chapel Hill, University of North Carolina Press, 1992), $43.95 (hb), $16.45 (pb).

Michael Leifer and John Phipps, Vietnam and Doi Moi: Domestic and International Dimensions of Reform, RIIA Discussion Paper No. 35 (London: The Royal Institute of International Affairs: 1991) 40 + ii pp. £5. ISSN 0951-4171.

Michael C. Williams, Vietnam at the Crossroads (London: Pinter Publishers for the Royal Institute of International Affairs, 1992) 104 + viii pp. £22.50 (hb); £8.95 (pb). ISBN 1-85567-051-8 (hb); 1-85567-052-6 (pb).

Neville Brown, The Strategic Revolution: Thoughts for the Twenty-First Century (Brassey's: London, 1992), 248 pp.     

The application of eight reported temperature-based algorithms to calculate the postmortem interval.

There exist numerous temperature-based techniques to calculate the early postmortem interval of human corpses. This paper presents eight commonly used time of death algorithms and describes how they were applied to eight corpses.