Examining the effect of dl-3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine on the Standardized Field Sobriety Tests

dl-3,4-methylenedioxymethamphetamine (MDMA) and methamphetamine are commonly used illicit drugs that are thought to impair driving ability. The Standardized Field Sobriety Tests (SFSTs) are utilized widely to detect impairment associated with drugs other than alcohol in drivers, although limited evidence concerning MDMA and methamphetamine consumption on SFST performance exists. The aim of this study was to evaluate whether the SFSTs were a sensitive measure for identifying the presence of the specific isomer d-methamphetamine and MDMA. In a double-blind, within-subject, counter-balanced and placebo-controlled study, 58 healthy and abstinent recreational drugs users were administered three treatments: 100mg of MDMA, 0.42 mg/kg d-methamphetamine, and placebo. For each condition the SFSTs were administered at 4 and 25 h post treatment. d-methamphetamine was not found to significantly impair SFST performance unlike MDMA, which significantly impaired SFST performance in comparison to placebo with 22% of the sample failing the test at the 4h testing time-point. No differences were observed at the 25 h testing time-point for any of the conditions. It was concluded that the SFSTs are not efficient in identifying the presence of low level d-methamphetamine, and are significantly better at detecting the presence of MDMA at the levels assessed.     

Finding His Kronstadt: Howard Fast, 1956 and American Communism

The scholarship on the impact on communists of Khrushchev's “secret speech” to the twentieth Congress of the Communist Party of the Soviet Union in 1956 is limited. Generally it is located within broader studies of organisational upheavals and ideological debates at the leadership level of communist parties. Rarely has there been analysis of the reverberations at the individual level. Consistent with James R. Barrett's pioneering approach, this paper seeks to incorporate the personal into the political, and inject a subjective dimension into the familiar top‐down narrative of American communism. It will do this by focusing on the motivations, reactions and consequences of the defection of one Party member, the writer Howard Fast. It will thereby illuminate the story of personal anguish experienced by thousands in the wake of Khrushchev's revelations about Stalin.     

Mary Alice Haddad,Effective Advocacy: Lessons from East Asia’s Environmentalists

Journal of Chinese Political Science -     

Justifying Preventive Detention

Law and Philosophy -     

Single primer extension (SPEX) amplification to accurately genotype highly damaged DNA templates

High levels of non-authentic sequence data can be generated by traditional PCR-based methodologies when DNA is damaged, template numbers are small and/or the target amplification size too large. We therefore present an alternate methodology based on single primer extension (SPEX) amplification; that places no pre-defined size constraints on amplification and interacts with only one of the DNA strands at the target locus.