Artifacts in the GC-MS profiling of underivatized methamphetamine hydrochloride

When underivatized methamphetamine hydrochloride (MA.HCl) in methanol is subjected to the instant gas chromatographic-mass spectrometric (GC-MS) profiling with old inlet liners at temperatures above 200 degrees C, appreciable amounts of N,N-dimethylamphetamine (DMA) and amphetamine (AP) are produced. The presence of these two artifacts is attributed to the N-demethylation and N-methylation reactions of MA as well as methyl group exchange with methanol. These artifacts are only produced in old injection port liners and at elevated temperatures. The formation of artifacts is proportional to concentration of MA.HCl. It is suggested that special cautions and measures be undertaken to prevent artifacts.     

DEVELOPING A FRAMEWORK FOR MANAGEMENT EDUCATION IN THE VICTORIAN PUBLIC SERVICE

Abstract: The Public Service Board of Victoria initiated a project in March 1989 to plan a framework for the development of competent managers. The methodology involved an examination of the current practices of 23 organisations, together with a worldwide literature search. The major findings were that the managerial task is similar across sectors, but the manager level and the environment are qualifying variables; that training, management education and development in private sector organisations and statutory bodies has total commitment from the chief executive, is closely linked to the business plan, forms part of an integrated human resource management system, and is continually reinforced by the organisation's culture and values; and that there is no strategic and focused approach to developing managers across the Victorian Public Service. The 21 recommendations covered the areas of investment and commitment, the development of a systematic approach by providing quality management programs based on core managerial competencies and the integration of training, education and development with performance management processes.
The implementation plan calls for pump-priming funds for resourcing and delivering high quality programs, a change in the culture, the adoption of a set of principles, the establishment of a management education unit, acceptance of a common language of competence for managers, and an integration of education and development needs with corporate plans through the performance improvement system. Commitment to implementation should result in a systematic approach to the formation of competent managers with the benefits flowing to the community through improved services, the government gaining by increased performance of the agencies, and public servants being able to reach their full potential.     

Participatory modelling and development practice: artisanal fishers in Nicaragua

Development plans with insufficient knowledge about local realities, and that do not share technical or planning details with the target communities, bedevil development practice. This study used a form of participatory modelling in three fishing communities in Nicaragua to enable fishers to explore their economy and the potential impacts of fishery-based development projects. Co-designing a model of the fishing economy in the form of a board game created a forum in which facilitators and participants could arrive at a shared understanding of local fishing practices and the costs and benefits of strategies for addressing the fishers’ priorities.     

Cumulative Trauma,Personal and Social Resources,and Post-Traumatic Stress Symptoms Among Income-assisted Single Mothers

Data from 247 single mothers were used to partially validate a theoretical model that highlights the process through which post-traumatic stress disorder (PTSD) develops among women. Structural equation modeling was used to assess the direct and indirect relationship between cumulative trauma (CT) and mothers’ PTSD symptom severity. Additionally, we examined the meditational role played by mothers’ strains and resources and the moderating role played by mothers’ residence in an intersectionally advantaged versus disadvantaged neighborhood. A good fit was found between the hypothesized model and data. Mothers’ strains and personal resources played a significant mediating role in the relationship between CT and PTSD symptom severity. Neighborhood of residence did not moderate the CT-PTSD process. Implication for practice and treatment are discussed.