Screening analysis for medicinal drugs and drugs of abuse in whole blood using ultra-performance liquid chromatography time-of-flight mass spectrometry (UPLC-TOF-MS)-Toxicological findings in cases of alleged sexual assault

An ultra-performance liquid chromatography time-of-flight mass spectrometry (UPLC-TOF-MS) method for simultaneous screening of 46 medicinal drugs and drugs of abuse in whole blood was developed and validated. The method includes most of the commonly used and abused drugs such as amphetamines, cocaine, benzodiazepines, and opioids. Chromatographic separation of the targeted drugs was achieved using a Waters ACQUITY UPLC coupled to a Waters Micromass LCT Premier XE time-of-flight mass spectrometer. The total chromatographic run time was 13.5min injection to injection. The estimated method LOQ is in the range of 0.06-27ng/g, which is below the therapeutic levels for each of the drugs analyzed but LSD. The extraction recovery ranged from 6% to 197% with median value 95% and mean value 82%. Matrix effect ranged from 81% suppression to 29% enhancement of the signals compared to signals obtained in the absence of biological matrix. The method was tested on 55 authentic forensic toxicology samples confirming the same positive results as found using the routine analytical procedures as well as some additional compounds. Recently there has been considerable attention paid to drug-facilitated sexual assault and the toxicological findings in these cases. As part of a pilot study to investigate the prevalence of medicinal drugs, drugs of abuse, and alcohol in victims of alleged sexual assault, biological specimens were obtained from 167 victims being examined at the Sexual Assault Center in Aarhus, Denmark. The obtained blood samples were analyzed using the novel screening method supported by additional analyses for e.g. THC and alcohol. 124 victims reported they have been drinking alcohol prior to the assault (74%). Alcohol analyses revealed 59 positive findings (48%). 35 of the cases were found positive for one or more drugs excluding alcohol (21%). 20 of the victims reported they have been subject to a drug-facilitated sexual assault (12%). For the victims suspecting drug-facilitated sexual assault, the toxicological analyses revealed four positive for alcohol and nine victims were positive for one or more drugs, with six of the victims found positive for benzodiazepines or other drugs with sedative effects. It was notable that victims tested positive for medicinal drugs and drugs of abuse as well as victims of alleged drug-facilitated sexual assault in average underwent medical examination later than the whole study population.     

Isomorphic Forces and Professional Soccer Standardizations: Instruments of Governance for Municipal Investments?

This article aims to explain why Danish municipalities usually choose to comply with stadium requirements from the Danish Soccer Association (DBU) even though, in most cases, they do not have the supporter base that could fill the renovated or new stadiums to their capacities. Using institutional theory as a theoretical framework, the article shows that coercive forms of isomorphism are part of the homogenization process leading to the municipalities’ compliance. It also suggests that mimetic forms of isomorphism are present in the sense that municipalities believe that if they comply with these requirements they will strengthen the conditions of their local clubs. In turn, they have encouraged other municipalities to follow suit. In sum, the analysis shows that the central form of governance through standardizations together with isomorphic forces have contributed to a uniformity among the municipalities.     

Trust in Scandinavia: Findings from Moving Borders between Denmark and Germany

Scandinavian societies express the world's highest levels of trust in surveys and display high levels of social capital more generally. Scholars and policy makers disagree on whether this reflects high economic equality brought about by inclusive, universalist welfare states after the Second World War or historical legacies of political stability and relative social harmony. This article utilizes a geographic regression discontinuity (GRD) natural experiment from history of moving borders between Denmark and Germany to examine the effect of belonging to a Scandinavian state on trust and cooperative behavior. Results from historical Danish rule prior to 1864 in North Germany and German rule in South Denmark from 1864 to 1920 suggest that institutional differences influenced early mass political behavior, but not social behavior. However, such early regime impacts petered out quickly. Today, there is little to no discernable difference in trust attributable to Danish state heritage in North Germany or South Denmark. This suggests that sizable differences in social trust between Germany and Denmark are instead attributable to post‐1920 factors.     

Negative Campaigning in a Multiparty System

Research in political campaigning in Scandinavian countries is inadequate, and research in negative campaigning is entirely non‐existent. A ‘negative campaign message’ is defined as an explicit critique of the political opponent. Applying this definition to the 2005 Danish election indicates that negative campaigning comprises a very limited aspect of the political campaigning in the course of this election. The opposition tends to employ negative tactics the most in their attempts to establish their political platform. The media provided extensive coverage to the few negative campaign messages, thus presenting a biased sense of the political campaign to the general public. This biased media coverage encourages parties to ‘go negative’ in their respective campaigns in the battle for media attention.     

Acculturation, partner violence, and psychological distress in refugee women from Somalia

This study examined the relations among acculturation, domestic violence, and mental health in 62 married refugee women from Somalia. Refugees from Somalia constituted the largest group of refugees entering the United States in 2005, and little is known about the presence of domestic violence in this group. The results showed that women who reported greater ability to speak English also reported more experiences of partner psychological abuse and physical aggression. Experiences of more psychological abuse and physical aggressions also predicted more psychological distress. Implications for future research and psychological services are addressed.     

Trust and Legal Governance: A Case Study of Ethiopian Criminal Justice

Current empirical research on trust in criminal justice focuses on those who do the trusting. Working from the theoretical position that trust is relational, this article expands that research by showing how trust relationships between the public and criminal justice institutions are shaped by the legal framework governing them. Reporting empirical case studies from the plural legal governance of criminal justice in Ethiopia, the article shows that the country's different legal frameworks produce different constructions of trust relationships between the public and criminal justice institutions. Furthermore, the empirical study shows that the practical organization of daily case handling in criminal justice institutions make for an important mechanism to mediate and link these differently constructed trust relationships.     

Offending,drug abuse and life chances—a longitudinal study of a Stockholm birth cohort

There are many factors, both empirical and theoretical, which indicate that drug abuse can play an important role in explaining the links between criminality and life chances when viewed from a life-course perspective. In this article, we examine the links between crime and drug abuse and social inclusion and exclusion in adult life, and look at whether there are gender-specific patterns in these regards. The Stockholm Birth Cohort database allows us to follow a birth cohort born in 1953 to age 56. The results show that drug abuse is central both to processes of continuity in and desistance from crime and to life chances in adulthood. For the adult outcomes that relate to work and health, we also note a tendency towards polarization; the size of both the relative and the absolute differences between the comparison group and offenders with registered drug abuse increases over time. The same general pattern can be seen for males and females.     

From Learning to Labour to Learning to Self-Control: The Paradigmatic Change in Swedish Prison Policy

This article has been written from the position that we fail to understand the character of the changes in prison policy in the last decades if we concentrate too much on the new emphasis on control and security. By making use of Thomas Kuhn's paradigm model, the article argues that it is fertile to see the changes in Swedish prison policy during the last decades as a paradigm shift. Although the new emphasis on control and security is important, it is only one feature in a larger transformation which concerns changing perceptions of the criminal subject, new theoretical understandings, new treatment methods, as well as a new role for the prison in penal policy in general. The article conceptualizes the policy that has developed inside the Swedish Prison and Probation Service during the last decades as the developing of a new paradigm in contrast to the old prison policy paradigm of the welfare state. The article especially discusses the significance of the development of so-called evidence-based knowledge as well as the creation of a Scientific Council inside the Swedish Prison and Probation Service which have led to a re-pathologization of the criminal subject. Other features that make up the new paradigm are the numerous programmes built on cognitive therapy and the emphasis on individual risk assessments. On a general level, the new paradigm has developed during, and is congruent with, the dominance of a neo-liberal regime.     

Violence at Work—The Emergence of a Social Problem

This article analyses trends in violence at work on the basis of victim surveys, work-environment surveys, and press material. It proceeds from the two most common explanations of why violence at work appears to have increased over recent decades. These emphasize shifts in working conditions that have increased employees' victimization risk, and a broadened view of what is regarded as work-related violence. The empirical analyses provide support for both these explanations, and the various dimensions examined—increased reporting propensities, expanded definitions, a reduced tolerance of violence, and altered working conditions—are linked to one another.