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931.
The concentrations of zolpidem and zopiclone were determined in peripheral blood samples in two forensic materials collected over a 10-year period (2001-2010). The z-hypnotics were determined in venous blood from living subjects (impaired drivers) and in femoral blood from deceased persons (forensic autopsies), with the latter classified as intoxication or other causes of death. The z-hypnotics were determined in blood by capillary column gas chromatography (GC) with a nitrogen-phosphorous (N-P) detector after solvent extraction with n-butyl acetate. The analytical limit of quantitation (LOQ) was 0.02mg/L for zopiclone and 0.05mg/L for zolpidem and these have remained unchanged throughout the study. When death was attributed to drug intoxication (N=918), the median concentration of zopiclone in blood was 0.20mg/L compared with 0.06mg/L for other causes of death (N=1215) and 0.07mg/L in traffic offenders (N=691) (p<0.001). Likewise, a higher median concentration (0.30mg/L) was found in intoxication deaths involving zolpidem (N=357) compared with 0.13mg/L for other causes of death (N=397) or 0.19mg/L in impaired drivers (N=837) (p<0.001). Median concentration in blood of both z-hypnotics were appreciably higher in intoxication deaths when no other substances were identified; 0 70mg/L (N=12) for zopiclone and 1.35mg/L (N=12) for zolpidem. The median concentrations of z-hypnotics in blood decreased as the number of co-ingested substances increased for intoxication deaths but not other causes of death. The most prevalent co-ingested substances were ethanol in autopsy cases and diazepam in the motorists. This large compilation of forensic cases should prove useful when toxicologists are required to interpret concentrations of z-hypnotics in blood samples in relation to cause of death. 相似文献
932.
Offender behaviour is used to distinguish between crimes committed by the same person (linked crimes) and crimes committed by different people (unlinked crimes) through behavioural case linkage. There is growing evidence to support the use of behavioural case linkage by investigative organisations such as the police, but this research is typically limited to samples of solved crime that do not reflect how this procedure is used in real life. The current paper extends previous research by testing the potential for behavioural case linkage in a sample containing both solved and unsolved crimes. Discrimination accuracy is examined across crime categories (e.g. a crime pair containing a car theft and a residential burglary), across crime types (e.g. a crime pair containing a residential burglary and a commercial burglary), and within crime types (e.g. a crime pair containing two residential burglaries) using the number of kilometres (intercrime distance) and the number of days (temporal proximity) between offences to distinguish between linked and unlinked crimes. The intercrime distance and/or the temporal proximity were able to achieve statistically significant levels of discrimination accuracy across crime categories, across crime types, and within crime types as measured by Receiver Operating Characteristic (ROC) analysis. This suggests that behavioural case linkage can be used to assist the investigation, detection and prosecution of prolific and versatile serial offenders. 相似文献
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Plague is a deadly disease of obvious concern to individuals, communities, and public health officials. The rapid recognition of plague victims is of paramount importance in saving the lives of the victims and in the protection of contacts. Three autopsied plague cases have been presented and the pathological features have been discussed. 相似文献
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E. Terrence Jones 《Journal of criminal justice》1976,4(4):333-340
A longitudinal analysis of the changes in crime rates between the late 1950s and 1970 in the 155 largest U.S. cities indicates that (1) there is virtually no relationship between the four major crimes against persons although there is strong mutual association between the four major crimes against property; (2) changes in racial composition account for more variation in changes in crime than do changes in income, thereby suggesting the need for more detailed studies of the noneconomic ways in which a city's racial composition affects crime incidence; and (3) there is a modest relationship between changes in the number of male youth and changes in certain types of crime. Since these findings are based on highly aggregated data with both known and unknown measurement errors, they must be treated cautiously. 相似文献