Aging of wound healing in an experimental model in mice

Healing of incised wounds in the backs of mice was studied to establish criteria that would allow the timing of stages during cutaneous wound healing. Starting from day 4 after the incisions were made, three mice were killed every 3 days until day 40. Sections from wounds were stained with hematoxylin-eosin, a reticulin procedure, and picrosirius red. Unstained sections were used for blue autofluorescence. The significance of the findings from the ultraviolet study was limited, but the picrosirius red-polarized light procedure was found to be useful for estimating the age of the repair process as polarization colors of greater wavelengths progressively increased with the age of the lesion.     

Repeat victimization among adolescents and young adults

Prior research has shown that victimization incidents are disproportionately concentrated among relatively few victims and that prior victimization is a consistent predictor of future risk. This paper expands existing knowledge on victimization by describing temporal patterns of risk and by developing and testing alternative explanatory models of the link between past and future risk. Analyses based on panel data from the National Youth Survey support both state dependence and heterogeneity interpretations of the correlation in risk over time. In other words, prior victimization predicts future risk in part because it alters something about the individual, and because it indicates an unmeasured propensity for victimization that persists over time. The theoretical implications of these findings, including the feasibility of a victim labeling perspective, are discussed.An earlier version of this paper was presented at the annual meeting of the American Society of Criminology, Phoenix, 1993.An exception to this lack of attention is the vast literature in the area of domestic abuse.     

Age as a basis for allocating lifesaving medical resources: an ethical analysis

In light of the growing prominence of an age criterion in patient selection, it is essential to scrutinize the ethical legitimacy of arguments being offered both for and against using age as a criterion. Accordingly, the present study first explores the primary justifications for an age criterion, then examines the criterion's weaknesses. Weaknesses are grouped into two areas: deficiencies in the justifications of the criterion, and overarching critiques. Finally, a way forward in the midst of the present controversy is suggested. The study's conclusion is that an age criterion per se is unjustified, though age may play a carefully defined role in medical assessments relevant to patient selection.