Estimating Individual Contributions to Complex DNA SNP Mixtures.,

High‐throughput sequencing (HTS) of large panels of single nucleotide polymorphisms (SNPs) provides an alternative or complimentary approach to short tandem repeats (STRs) panels for the analysis of complex DNA mixture forensic samples. For STRs, methods to estimate individual contribution concentrations compare capillary electrophoresis peak heights, peak areas, or HTS allele read counts within a mixture. This article introduces three approaches (mean, median, and slope methods) for estimating individual DNA contributions to forensic mixtures for HTS/massively parallel sequencing (MPS) SNP panels. For SNPs, the major:minor allele ratios or counts, unique to each contributor, were compared to estimate contributor proportion within the mixture using the mean, median, and slope intercept for these alleles. The estimates for these three methods were typically within 5% of planned experimental contributions for defined mixtures.     

Bottom-level organizational changes within entrepreneurial and engaged models of university: insights from Italy

We analyze the way in which individual academics and research groups organize their third mission activities before and after the institutionalization of third mission strategies by the university governing body. Drawing on the literature, we put forward an interpretative framework that links central entrepreneurial or engaged strategies with the way academics organize their third mission activities. Then, we propose an application of this frame to the case of the University of Florence (Italy), before and after its transition to more structured entrepreneurial and engaged models. We use a mix of quantitative and qualitative analysis. A cluster analysis allows identifying different types of academics involved in the third mission based on the way they organize their activities. Furthermore, a set of interviews to academics complements the comparison and the interpretation of the clusters obtained. The following paths of change emerge: (1) increased proportion of academics involved in third mission activities; (2) bottom-level initiatives that are aligned with central strategies; and (3) increased heterogeneity of bottom-level organization forms, with a relative loss of importance of the group dimension with respect to the individual academics and an increased specialization of research groups.

     

Relational Aggression at School: Associations with School Safety and Social Climate

The present study examines how exposure to relational aggression at school is associated with adolescents’ perceptions of, and participation in, a hostile school environment. Participants were 1,335 African American and European American adolescents in grades 7 through 12 (52% female, 49% African American). Results indicate that exposure to relational aggression is associated with several components of adolescents’ perceptions of the school climate. Adolescents exposed to high levels of relational aggression perceived their school to be less safe, and were less pleased with the general social atmosphere at school. Moreover, for males, but not females, exposure to relational aggression was associated with carrying a weapon to school. Implications and suggestions for future research are discussed in terms of working toward safer school environments for adolescents.

Owning the issue agenda: Party strategies and vote choices in British elections

Explanations of party competition and vote choice are commonly based on the Downsian view of politics: parties maximise votes by adopting positions on policy dimensions. However, recent research suggests that British voters choose parties based on evaluations of competence rather than on ideological position. This paper proposes a theoretical account which combines elements of the spatial model with the ‘issue ownership’ approach. Whereas the issue ownership theory has focused mainly on party competition, this paper examines the validity of the model from the perspective of both parties and voters, by testing its application to recent British general elections. Our findings suggest that as parties have converged ideologically, competence considerations have become more important than ideological position in British elections.     

Quality Management in Public-Sector Organizations: Evidence from Six EU Countries

Although there is considerable evidence for the hypothesis that an efficient use of management techniques is the key to a good public service delivery, a lot of studies come to the conclusion that there is only partial, reluctant implementation or even a general lack of the use of such techniques by public managers. This paper examines the determinants for the use of quality management techniques in public sector organizations from six EU countries. It turns out that especially more organizational autonomy and result control appear to be of importance while, surprisingly, the combination of these variables leads to negative results.     

Experimental Evidence on the Impacts of Need-Based Financial Aid: Longitudinal Assessment of the Wisconsin Scholars Grant

We conduct the first long-term experimental evaluation of a need-based financial aid program, the privately funded Wisconsin Scholars Grant. Over multiple cohorts, the program failed to increase degree completion and graduate school enrollment up to 10 years after matriculation. The program did reduce time-to-degree for some students and modestly increased the number of STEM degrees earned. The lack of robust effects raises important questions about the conditions necessary for financial aid to benefit students.     

Causal inference and American political development: contrasts and complementarities

Public Choice - Causal inference and American political development (APD) are widely separated and (to some) fundamentally incompatible tendencies within political science. In this paper, we...