What challenges offers nanotechnology to bioethics?

Though nowadays science means progress, for some people it means a moral danger. However, the progress should not be suppressed, and in every case, it should be controlled. These authors uphold that science and morality are closely linked and complementary. That is, technology, society and morality, by themselves, do not have the absolute truth and must be complemented among them without any of the three being suppressed.     

Inferring ancestral origin using a single multiplex assay of ancestry-informative marker SNPs

Tests that infer the ancestral origin of a DNA sample have considerable potential in the development of forensic tools that can help to guide crime investigation. We have developed a single-tube 34-plex SNP assay for the assignment of ancestral origin by choosing ancestry-informative markers (AIMs) exhibiting highly contrasting allele frequency distributions between the three major population-groups. To predict ancestral origin from the profiles obtained, a classification algorithm was developed based on maximum likelihood. Sampling of two populations each from African, European and East Asian groups provided training sets for the algorithm and this was tested using the CEPH Human Genome Diversity Panel. We detected negligible theoretical and practical error for assignments to one of the three groups analyzed with consistently high classification probabilities, even when using reduced subsets of SNPs. This study shows that by choosing SNPs exhibiting marked allele frequency differences between population-groups a practical forensic test for assigning the most likely ancestry can be achieved from a single multiplexed assay.     

New identification criteria for the Chilean population: Estimation of sex and stature

In the analysis of human skeletal or otherwise unidentifiable remains the assessment of sex is an initial vital element when rendering a biological profile. As such other aspects of the biological profile are sex-specific (e.g. stature and age) and cannot be successfully determined without this preliminary assessment. In addition, the estimation of stature is an essential parameter of the biological profile, which is often used to confirm or exclude presumptive identifications.The purpose of this study is to present newly developed local identification criteria for the estimation of sex from the postcrania and stature for Chileans. Linear discriminant functions were derived for the humerus and femur. Sexing accuracies of 87%, 86%, and 82% were achieved. Furthermore, new univariate predictive stature equations are presented using a Bayesian approach for the humerus, femur and tibia.     

Environmental Concerns in Contemporary Brazil: An Insight into Some Theoretical and Societal Backgrounds (1970s–1990s)

This article intends to unveil some of the main theoretical backgrounds and current tendencies of environmental sociology in Brazil. But we are mainly interested in providing a historical reconstruction of the societal internalization of environmental concerns in Brazil, on both state and civic levels, with an emphasis on the transformations that took place over the 1970–1990s period. We argue that environmental civil associations do not find either a legal idiom or public forums by means of which they could turn their demands and moral concerns into a binding juridical code. This is so because, on the one hand, their moral concerns, even when based on de-traditionalized and abstract principles, are not paralleled with an autonomous legal framework, strong enough to set limits to the functioning of both the political-administrative apparatus as well as to economic actors. As we contend, this helps to explain why the environmental legislation in Brazil is rhetorically manipulated on a regular basis—and, hence, set aside whenever it contradicts other priorities. On the other hand, environmental concerns have always met with difficulties to become a priority in the Brazilian polity. Ultimately, our main goal is to carry out a critical consideration of the theoretical links that are widely set in the field of sociological theory between environmental concerns and modernity.     

Guantánamo Bay: Towards Legality?

This article outlines the US Supreme Court's approach to the habeas corpus entitlements of suspected terrorists detained in Guantánamo Bay and argues for the extension of constitutional habeas corpus rights to them. The article considers two ways in which the Supreme Court might carry out this task: first, 'the territorial approach' (based on domestic legal principles of 'unincorporated territories' and principles of leasehold), and secondly, 'the extraterritorial approach' (based on international purposive approaches to the reach of human rights treaties exemplified by the European Court of Human Rights' Article 1 jurisprudence). For reasons of effectiveness of protection, the Article expresses a clear preference for the latter. The House of Lords decision in R (Al-Skeini) v Secretary of State for Defence (2007) is proposed as a template for such a development. Finally the article refutes arguments rejecting such a development based on the 'trade-off thesis' and perceptions of judicial competence.     

Allele frequency distribution for 21 autosomal STR loci in Bhutan

We studied the allele frequency distribution of 21 autosomal STR loci contained in the AmpFlSTR^® Identifiler™ (Applied Biosystems), the Powerplex^®16 (Promega) and the FFFL (Promega) multiplex PCR kits among 936 individuals from the Royal Kingdom of Bhutan. As such these are the first published autosomal DNA results from this country.     

Beyond Borders

Asian nations seek cooperation in the face of the financial crisis As the global financial crisis continues to spread worldwide, its impact on the member states of the Association of Southeast Asian Nations (ASEAN) and the ASEAN Plus Three countries-China, Japan and South Korea-is deepening, according to a semi-annual report recently released by the East Asian Economic News of the World Bank Faced with slumping exports and other challenges, Asian countries have come up with huge bailout packages in an ef...     

The influence of bankruptcy law on equity value of financially distressed firms: A European comparative analysis

The reaction of stock prices to bankruptcy filing has been frequently analysed in the financial literature. In this paper we adopt a different approach to that of traditional study, and endeavour to determine whether the reaction of markets is conditioned by the orientation of bankruptcy law. Our results lead us to conclude that it is actually the type of bankruptcy law that conditions the valuation of firm's stocks. We have also found that the drop in share value is greater in creditor-oriented systems, while the negative returns are lower in debtor-oriented systems.