High performance liquid chromatographic determination of alcohols with reference to body distribution of methanol.

A method has been developed on reverse phase high performance liquid chromatography for simultaneous determination of methyl, ethyl and isopropyl alcohols under refractive index detection using pure water as the mobile phase. A good separation has been achieved between these alcohols. Detector response was linear with a detection limit of 5 mg/100 ml. Recovery studies were performed by adding known amounts of methyl and ethyl alcohols to blood, lung and liver within the range 80-90%. The reproducibility of the results was always greater than 90%. The quantitative distribution of methyl alcohol in postmortem body tissues and fluids has been reported in three cases of poisoning.     

How MDMA flows across the USA: evidence from price data

This study uses wholesale prices of MDMA for 59 cities in the USA published by the National Drug Intelligence Center (NDIC) over the period of 2002–2011 to identify trafficking patterns of MDMA. Price differentials and correlations between pairs of cities are used to infer the presence of a link and the direction of flow of MDMA. The presence of inward and outward links is used to categorise each city as a ‘source’, ‘destination’, ‘transit’, or ‘weakly integrated’ city. The analysis identified low prices close to the Canadian and Mexican borders, in a number of cities such as Chicago, Miami, New York City, a trio of cities in the Carolinas, and along the West Coast. A number of these cities are linked to large numbers of other cities, indicating hub- or source-like status. The findings generate insights into the status of major US cities in the MDMA trafficking network.     

Documents Received

Publications Received

Documents Received     

Topic Modeling the Research‐Practice Gap in Public Administration

The possible existence of a research‐practice gap is the topic of a long‐standing debate in the field of public administration. In this Viewpoint essay, the authors examine the agendas of scholars and practitioners using the topic modeling technique of computational social science. Topic modeling a content analysis of 35 topics identified in Public Administration Review and PA Times (3,796 articles) showed that just over 50 percent of topics were common to both groups, indicating shared interests. There were, however, topics that the two groups distinctly focused on. Moreover, scholars and practitioners attached significant differences to the weights allocated to the prominent topics in their writing. Taken together, these findings indicate that topic modeling can shed new light on the research‐practice gap in public administration.