Genetic variation of 13 STR loci in the four endogamous tribal populations of Eastern India

We have analysed 13 autosomal STR loci in four endogamous tribal populations from two eastern states (Orissa and Nagaland) of India. The Gadaba, Kuvi Khond and Lotha Naga populations have not been analysed for microsatellite genetic variation previously. The allele frequencies for all loci are within the range observed in the geographical region and racial background, though some alleles showed greater variation. Departures from the Hardy-Weinberg equilibrium were tested by three methods and two loci (THO1 and TPOX) showed significant departures for all measures in Gadaba and Lotha Naga populations. The exclusion probability and discrimination probability were high for all analysed loci in all populations. There is no evidence for association of alleles among the STR loci studied. This allele frequency information will be useful for forensic, paternity and population genetic studies.     

Genetic polymorphisms of 15 STR loci in two Tibetan populations from Tibet Changdu and Naqu, China

The allelic distribution of 15 short tandem repeat (STR) loci included in the AmpFl STR Identifiler kit was examined in 100 Changdu Tibetan and 118 Naqu Tibetan unrelated individuals living in the Tibet Province, PR China. The distribution of these observed genotypes was not significantly different from the expected distribution according to Hardy-Weinberg equilibrium.     

行政法的潮涨潮落

理论学派的法律是一个在认知上并不可靠的领域。它所采用的方法和视角已经受到当下政治和观念的冲击,并且因缺乏理论与实践的互动而显得摇摆不定。在本文中,我将阐述这一看似荒谬的结论,即:随着学术界与司法界不断改变对行政法形态和价值的塑造,法律将通过不断的去法化和日趋经     

Emotional distress in African American women with HIV

This study identified factors associated with emotional distress in 109 African American women with HIV. The relationship of personal factors (demographic, social conflict, social support, and spirituality), health-related factors (perception of health, physical and mental health problems, and years diagnosed), and cognitive/coping responses (stigma, worry, and emotion focused coping) on depressive symptoms and mood state was examined. Younger age, more social conflict, less social support, lower perception of health, and more HIV worry were associated with higher depressive symptom scores. Variables most often affecting various mood states included personal factors (public housing, unemployment, and social conflict) and worry about having HIV worry.     

Examination of a long-term clozapine administration by high resolution segmental hair analysis

The long-term administration of clozapine could be verified by fine segmentation and analysis of single hairs of one person to examine the history of a multiple poisoning case. Segments of 1-2.5mm length were extracted by ultrasonification in 30 microl of the mobile phase (mixture of methanol+water, 50+50). By application of isocratic liquid chromatography and using narrow bore columns (Synergy Polar-RP, Phenomenex), an acceleration and miniaturization of the HPLC-MS-MS assay could be achieved. Total amounts of clozapine down to 30 fg (on column) and its desmethyl metabolite could be analysed in multiple reaction monitoring mode. According to typical sample amounts of approximately 16 microg, relevant hair concentrations higher than 1 pg/mg were detected. Significant and reproducible concentration profiles along the hair fibres revealed characteristic administration cycles. The administration time course - in particular the time of its termination - could be verified with a precision of a few days. The accuracy and reproducibility of the concentration profile was proven based on multiple investigations of single hairs. An individual hair growth rate of 0.55 mm/day was determined with a relative standard deviation of 8% by comparison of concentration profiles in hairs collected after a time span of 165 days.     

Max Frei theory revisitation: does really strokes depth change along time?

A serious problem in questioned document examination is to establish the age of written lines. With respect to paper dating, in the past, Max Frei theory (based only on microscope analysis) claimed that strokes are time-dependent. Therefore, according to this theory, it has been asserted that from the analysis of the strokes depth changes it is possible to try to date the handwritten document (to find out that the document is older than ...). In the present work, we investigate the strokes depth change by a laser profilometer considering not only the time but also microclimatic variations. First, we analyze the stability of stroke characteristics along the time. In particular, we demonstrate that if the document is preserved without change of temperature and humidity, the depth of the strokes has not appreciable changes. In this way, we have the purpose to verify the real possibility of documents dating by means of Max Frei theory. Subsequently, we test how the 3D profile of strokes changes in connection with the microclimatic variations. In particular, we test humidity variations. With this experiment, we show that humidity variations reduce the strokes depth. Moreover, this effect shows a non-linear trend, leaving a hysteresis on the depth. Finally, we show that the analysis of 3D stroke profile is unable to determine the age of documents.     

英国-j◆效族奢青年身份认同与促进融合研究

有关少数族群融合问题的讨论,实际上是有关民族国家。如何在保障和维护少数族裔的权利的同时,缓解族群文化差异与统一的公民身份意涵之间矛盾冲突的讨论。作为现在乃至未来的国家公民,青年群体及其社会融合便成为这些讨论的焦点。围绕“公民身份”概念,了解不同族群青年人对此概念的理解,探讨青年人将“公民身份”建构成“问题”的过程,从而揭示缺乏公正、不被认可和自我决策困难等因素怎样影响了英国青年人成员身份感和归属感的形成,并提出了可能的政策建议和改善方法。     

Reducing Adverse Childhood Experiences (ACE) by Building Community Capacity: A Summary of Washington Family Policy Council Research Findings

Community capacity for organization and collaboration has been shown to be a powerful tool for improving the health and well-being of communities. Since 1994 the Washington State Family Policy Council has supported the development of community capacity in 42 community public health and safety networks. Community networks bring local communities together to restructure natural supports and local resources to meet the needs of families and children, and increase cross-system coordination and flexible funding streams to improve local services and policy. In this study, researchers sought to demonstrate the strong impact of the community networks' capacity to interrupt health and social problems. Findings suggest that community networks reduce health and safety problems for the entire community population. Further, community networks with high community capacity reduced adverse childhood experiences (ACE) in young adults ages 18-34.     

"Fast-track" strategies in long-term public disability programs around the world

Long-term public disability programs in the United States and several other countries have incorporated fast-track (FT) procedures that share a common goal of accelerating applicants through various stages of the disability determination process--generally for those with severe disabilities, blindness, or terminal illness. This article identifies a variety of FT procedures either implemented or under consideration in public long-term disability programs operated in the United States and other countries; compares FT procedures in those disability programs with respect to specific program features, differences with respect to the administrative components involved in those procedures, and the level of technology used; examines more generally why countries may consider implementing FT procedures; and describes how FT procedures may be employed to improve overall processing of claims and contribute to disability case management.     

社会需求导向下公共管理类本科人才培养目标的再定位——以陕西省高校为例

当前公共管理类本科人才培养模式不能完全适应社会需求的根本原因是培养目标与社会需求脱节。应理清学术型人才与应用创新型人才划分、应用创新型人才层次与高校类型等问题。创新公共管理类本科人才培养模式,必须以需求为导向,对培养目标进行再定位,即从社会需求出发,将当前单一学术的"h"型的培养目标转变为应用创新的"H"型公共管理类本科人才培养目标。并通过对培养规格的再定位,建立与社会需求相适应的应用创新能力结构、知识结构和素质结构,使公共管理类本科人才成为既适应政府部门,又适应非政府部门和企事业组织的应用创新型人才。