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61.
Forensic value of 14 novel STRs on the human Y chromosome 总被引:29,自引:0,他引:29
Redd AJ Agellon AB Kearney VA Contreras VA Karafet T Park H de Knijff P Butler JM Hammer MF 《Forensic science international》2002,130(2-3):97-111
We identified and characterized 14 novel short-tandem-repeats (STRs) on the Y chromosome and typed them in two samples, a globally diverse panel of 73 cell lines, and 148 individuals from a European-American population. These Y-STRs include eight tetranucleotide repeats (DYS449, DYS453, DYS454, DYS455, DYS456, DYS458, DYS459, and DYS464), five pentanucleotide repeats (DYS446, DYS447, DYS450, DYS452, and DYS463), and one hexanucleotide repeat (DYS448). Sequence data were obtained to designate a repeat number nomenclature. The gene diversities of an additional 22 Y-STRs, including the most commonly used in forensic databases, were directly compared in the cell line DNAs. Six of the 10 most polymorphic markers include the newly identified Y-STRs. Furthermore, these novel Y-STRs greatly improved the resolution of paternal lineages, above the level obtained with commonly used Y-STRs, in the European-American population. 相似文献
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Injuries observed in the facial skull area (FSA) in trauma made by hard blunt objects are registered within the forensic medical examinations of cadavers by far more rare than they are actually encountered in life. At the same time, a statement made to the effect that it was FSA that was affected in injuries of the cerebral skull area (CSA) is of an important forensic medical value. According to our research, the "strength beams" present in FSA and CSA are ovals and semi-ovals positioned above one another in 3 layers (top, medium and low ones). The anterior sections of all layers of FSA "strength beams" and of adjoining CSA regions, i.e. the squama of frontal bone (low one third of it) as well as anterior and middle cranial fossas, are a single deformative strength system. Specific features of each impact-zone region affect greatly a character of injuries in FSA at traumas in the medium facial third. Bones in the anterior and middle cranial fossas are damaged, apart from cranial injuries, in certain variations of impacts to FSA. 相似文献
66.
Melent'ev AB 《Sudebno-meditsinskaia ekspertiza》2001,44(4):28-31
Gas chromatography--mass spectrometry is proposed for measuring clofelin (clonidine) in cadaveric blood. The method includes liquid-liquid extraction of clonidine from the blood, derivatization with pentafluorobenzyl bromide, and subsequent purification of derivatization products before chromatographic analysis. The range of 0.5-50.0 ng/ml covers therapeutic and lethal concentrations of clonidine in the blood. The method was tried on expert material in Chelyabinsk Regional Bureau of Forensic Medical Expert Evaluations and can be used in forensic chemical and toxicological analysis. 相似文献
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Abstract: Tooth crown dimensions are reasonably accurate predictors of sex and are useful adjuncts in sex assessment. This study explores the utility of buccolingual (BL) and mesiodistal (MD) measurements in sex differentiation when used independently. BL and MD measurements of 28 teeth (third molars excluded) were obtained from a group of 53 Nepalese subjects (22 women and 31 men) aged 19–28 years. Stepwise discriminant analyses were undertaken separately for both types of tooth crown variables and their accuracy in sex classification compared with one another. MD dimensions had recognizably greater accuracy (77.4–83%) in sex identification than BL measurements (62.3–64.2%)—results that are consistent with previous reports. However, the accuracy of MD variables is not high enough to warrant their exclusive use in odontometric sex assessment—higher accuracy levels have been obtained when both types of dimensions were used concurrently, implying that BL variables contribute to sex assessment to some extent. Hence, it is inferred that optimal results in dental sex assessment are obtained when both MD and BL variables are used together. 相似文献
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Barbosa AB da Silva LA Azevedo DA Balbino VQ Mauricio-da-Silva L 《Journal of forensic sciences》2008,53(1):142-146
The sequences of the two hypervariable (HV) segments of the mitochondrial DNA (mtDNA) control region were determined in 167 randomly selected, unrelated individuals living in the state of Alagoas, north-eastern Brazil. One hundred and forty-five different haplotypes, associated with 139 variable positions, were determined. More than 95% of the mtDNA sequences could be allocated to specific mtDNA haplogroups according to the mutational motifs. Length heteroplasmy in the C-stretch HV1 and HV2 regions was observed in 22 and 11%, respectively, of the population sample. The genetic diversity was estimated to be 0.9975 and the probability of two random individuals presenting identical mtDNA haplotypes was 0.0084. The most frequent haplotype was shared by six individuals. All sequences showed high-quality values and phantom mutations were not detected. The diversity revealed in the mitochondrial control region indicates the importance of this locus for forensic casework and population studies within Alagoas, Brazil. 相似文献
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Quinlivan DS Neuschatz JS Jimenez A Cling AD Douglass AB Goodsell CA 《Law and human behavior》2009,33(2):111-121
After viewing or hearing a recorded simulated crime, participants were asked to identify the offender’s voice from a target-absent
audio lineup. After making their voice identification, some participants were either given confirming feedback or no feedback.
The feedback manipulation in experiment 1 led to higher ratings of participants’ identification certainty, as well as higher
ratings on retrospective confidence reports, in both the immediate and delay groups. Earwitnesses who were asked about their
identification certainty prior to the feedback manipulation (experiment 2) did not demonstrate the typical confidence-inflation
associated with confirming feedback if they were questioned about the witnessing experience immediately; however, the effects
returned after a week-long retention interval. The implications for the differential forgetting and internal-cues hypotheses
are discussed. 相似文献