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121.
The Limits of Disclosure: What Research Subjects Want to Know about Investigator Financial Interests
Christine Grady R.N. Ph.D. F. A.A.N. Elizabeth Horstmann Jeffrey S. Sussman M.P.H. Sara Chandros Hull Ph.D. 《The Journal of law, medicine & ethics》2006,34(3):592-599
Research participants' views about investigator financial interests were explored. Reactions ranged from concern to acceptance, indifference, and even encouragement. Although most wanted such information, some said it did not matter, was private, or was burdensome, and other factors were more important to research decisions. Very few said it would affect their research decisions, and many assumed that institutions managed potential conflicts of interest. Although disclosure of investigator financial interest information to research participants is often recommended, its usefulness is limited, especially when participation is desired because of illness. 相似文献
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The first measurements of differential mortality by sex took place at the end of the seventeenth century. Once its existence has been clearly shown during the eighteenth century by the works of Struyck, Kersseboom, Süssmilch, Deparcieux and others, what analysis emerged? If one of the two sexes benefited from a longer life, was this rule valid in all places and for all ages? All the demographers observed that such a difference began during infancy and childhood. How can it be explained that children were not equal in the face of death? Why did so many boys die before their teenage years? We can find several types of explanation: the will of God, the natural order, the biological constitution and the social habits of children of more than one year old. 相似文献
126.
Karl Wärneryd 《Public Choice》1994,80(3-4):371-380
Intuitively, we associate different political parties with different types of policy. In contrast, this paper shows that in the absence of differential costs of membership among parties (that is, if party membership ischeap talk), party labels cannot perfectly signal the ideologies of candidates. However, under certain conditions parties can signal candidate types imperfectly. The paper therefore also provides an example of how costless communication can be effective in games of partial conflict. 相似文献
127.
Annika Brändström 《Scandinavian political studies》2015,38(3):301-320
Accountability processes after crisis events sometimes entail harsh criticism from public and political players alike, forcing cabinet ministers to be on top of the political game and sometimes even resign. However, harsh accountability processes are just as likely to leave ministers undamaged. This article combines two existing theories that propose different factors to account for variation in outcomes: ministerial resignations as a consequence of cabinet formation and individual positions; or resignations as a result of blame management strategies involving individual actors within the cabinet and beyond. Ten crisis episodes in Sweden are analysed and compared. The findings suggest that individual political power bases and experience matter to how well blame management strategies can be employed, while the composition of the government gives structural constraints. The dynamic interplay and framing battle between incumbent decision makers, and external arenas and the skill with which individual ministers engage and frame responsibility, play a key role in determining their post‐crisis careers. 相似文献
128.
Assessment of Maceration Techniques Used to Remove Soft Tissue from Bone in Cut Mark Analysis
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Maceration techniques employed in forensics must be effective without compromising the bone's integrity and morphology, and prevent destruction of evidence. Techniques must also be fast, safe, easily obtainable and inexpensive; not all techniques currently employed are appropriate for forensic use. To evaluate the most suitable approach, seven techniques including current and new methodologies were applied to fresh, fleshed porcine ribs exhibiting cut marks. A sample size of 30 specimens per technique was examined under scanning electron microscopy at the cut mark and the surrounding uncompromised regions; a scoring system of effectiveness was applied. The previously unpublished microwave method fared best for bone and cut mark preservation. Sodium hypochlorite destroyed cut marks, and was deemed unsuitable for forensic analysis. No single technique fulfilled all criteria; however, this study provides a benchmark for forensic anthropologists to select the most appropriate method for their situation, while maintaining the high standards required by forensic science. 相似文献
129.
Björn Bäckström M.D. Bengt Johansson M.D. Ph.D. Anders Eriksson M.D. Ph.D. 《Journal of forensic sciences》2015,60(6):1662-1665
Nitrous oxide is an inflammable gas that gives no smell or taste. It has a history of abuse as long as its clinical use, and deaths, although rare, have been reported. We describe two cases of accidental deaths related to voluntary inhalation of nitrous oxide, both found dead with a gas mask covering the face. In an attempt to find an explanation to why the victims did not react properly to oncoming hypoxia, we performed experiments where a test person was allowed to breath in a closed system, with or without nitrous oxide added. Vital signs and gas concentrations as well as subjective symptoms were recorded. The experiments indicated that the explanation to the fact that neither of the descendents had reacted to oncoming hypoxia and hypercapnia was due to the inhalation of nitrous oxide. This study raises the question whether nitrous oxide really should be easily, commercially available. 相似文献
130.
Although there seems to be a broad consensus among economists that purely floating or completely fixed exchange rates (the so-called corner solutions) are the only viable alternatives of exchange rate management, many countries do not behave according to this paradigm and adopt a strategy within the broad spectrum of exchange rate regimes that is limited by the two corner solutions. Many of these intermediate regimes are characterized by significant foreign exchange market interventions and a certain degree of exchange rate flexibility with non-preannounced exchange rate targets. While academic research in this area usually concentrates on some specific aspects of intermediate regimes (such as the effectiveness of interventions or institutional aspects), managed floating has rarely been analyzed as a comprehensive monetary policy strategy. In this paper, we present a monetary policy framework in which central banks simultaneously use the exchange rate and the interest rate as operating targets of monetary policy. We explain the mechanics of foreign exchange market interventions and sterilization and we explain why a central bank has an interest of controlling simultaneously the two operating targets. We derive the monetary policy rules for the two operating targets from a simple open economy macro model in which the uncovered interest parity condition and the monetary conditions index play a central role. 相似文献