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121.
Due to the circumstances in some forensic cases, very small amounts of DNA (<100 pg) may be obtained. This, in turn, may affect the reliability of the PCR process, and so it may be advisable to repeat the amplification process for confirmatory purposes. Gill et al. [Forensic Sci. Int. 112 (2000) 17] proposed a method for the statistical evaluation of the PCR replicate information. In this paper we formalize the method proposed by Gill et al. [Forensic Sci. Int. 112 (2000) 17], and extend it to allow for cases involving mixed stains and for population substructure. 相似文献
122.
James Curran 《澳大利亚政治与历史杂志》2002,48(4):469-486
This paper is concerned with the way in which Australian prime ministers gave expression to an idea of “national community” in the post–1972 era. With the declining relevance of the British connection, the departure of “great and powerful” friends from the region, the imperative of engagement with Asia and the emerging concept of Australia as a “multicultural” society, one of the central challenges for these leaders has been whether or not they could offer an alternative myth of community which would preserve social cohesion in the new times. This raises an important historical question concerning Australian political culture at this time — what happened to the need for nationalism? By examining the speeches of Prime Ministers Whitlam, Fraser, Hawke and Keating, it can be seen that far from asserting an old–style, exclusive Australian nationalism, in most cases these leaders expressed great caution and hesitation towards the idea of nationalism itself. 相似文献
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Davia T. Hudson Ph.D. Allison M. Curran Ph.D. Kenneth G. Furton Ph.D. 《Journal of forensic sciences》2009,54(6):1270-1277
Abstract: Human scent evidence collected from objects at a crime scene is used for scent discrimination with specially trained canines. Storage of the scent evidence is usually required yet no optimized storage protocol has been determined. Storage containers including glass, polyethylene, and aluminized pouches were evaluated to determine the optimal medium for storing human scent evidence of which glass was determined to be the optimal storage matrix. Hand odor samples were collected on three different sorbent materials, sealed in glass vials and subjected to different storage environments including room temperature, ?80°C conditions, dark storage, and UVA/UVB light exposure over a 7‐week period. Volatile organic compounds (VOCs) in the headspace of the samples were extracted and identified using solid‐phase micro‐extraction–gas chromatography/mass spectrometry (SPME–GC/MS). Three‐dimensional covariance mapping showed that glass containers subjected to minimal UVA/UVB light exposure provide the most stable environment for stored human scent samples. 相似文献
126.
Patrice Flynn Martcia Wade John Holahan 《Journal of policy analysis and management》1997,16(2):219-236
Individual states are actively weighing health care reform proposals and their potential impacts on many levels, including states' own economies. This article considers the effects on state economies of two instruments of health reform: employer mandates and cost containment. The literature suggests that an employer mandate will reduce employees' wages in the long run. In the short run, however, to compensate for the costs associated with mandated health care insurance for their employees, firms may raise their prices to consumers, reduce the number of employees or allow a drop in profit margins. By increasing health care spending and the number of insured persons, mandates would also increase states' levels of economic activity. Though cost containment may dampen the stimulative effects of expanded coverage, resources not spent on health care as a result of effective cost containment might be redistributed to other sectors in a state's economy. 相似文献
127.
Abstract: Recent discussions on a forensic discussion group highlighted the prevalence of a practice in the application of inclusion probabilities when dropout is possible that is of significant concern. In such cases, there appears to be an unpublished practice of calculation of an inclusion probability only for those loci at which the profile of interest (hereafter the suspect) is fully included among the alleles present in the crime scene sample and to omit those loci at which the suspect has alleles that are not fully represented among the alleles in the mixture. The danger is that this approach may produce apparently strong evidence against a surprisingly large fraction of noncontributors. In this paper, the risk associated with the approach of ignoring loci with discordant alleles is assessed by simulation. 相似文献
128.
Nicola Farmer James Curran David Lucy Niamh Nic Daeid Wolfram Meier-Augenstein 《Science & justice》2009,49(2):107-113
Arson is a significant problem around the world, and is a crime which results in a low number of convictions. The scene of an arson can be varied, commercial, residential or national park, and recently cases have been identified which were initiated by a lit match. Matches can be recovered from a scene, usually in a burnt condition. The benefit of analysing unburnt matches has been researched previously [1,2]. In most cases, burnt matches are recovered from scenes, and therefore the research was extended to investigate the potential of using IRMS to analyse burnt matches. This includes samples which have been exposed to petrol, and various fire extinguishing chemicals.Matches were sectioned to reveal central unburnt portions of wood and analysed by isotope ratio mass spectrometry (IRMS). The stable isotope profile (SIP) of the wooden matchstick samples was unaffected by the presence of both petrol and a variety of fire extinguisher chemicals. Any changes seen could be attributed to the natural variability of isotopic composition encountered in a natural material such as wood. These findings were confirmed by the isotope analysis of 19 matchstick samples placed in mock fire training scenarios. The data was examined using a paired t-test and Hotellings T2 test for a single sample. 相似文献
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James M. Curran Simon J. Walsh John Buckleton 《Forensic Science International: Genetics Supplement Series》2007,1(3-4):267-272
Direct empirical testing of forensic DNA micro-probabilities has proved difficult. Substantial support for the population genetic models on which these micro-probabilities are based has come from powerful but indirect means. However for many people empirical testing rather than models remains the ideal.Following the example set by Weir and Evett we report here a large-scale empirical test of a population genetic model incorporating substructure and relatedness. Given that all models represent simplifications of reality the fit of observed and prediction is remarkable and gives substantial support to the reliability of current methods. 相似文献