Effect of Lower Third Molar Segmentations on Automated Tooth Development Staging using a Convolutional Neural Network

Staging third molar development is commonly used for age estimation in subadults. Automated developmental stage allocation to the mandibular left third molar in panoramic radiographs has been examined in a pilot study. This method used an AlexNet Deep Convolutional Neural Network (CNN) approach to stage lower left third molars, which had been selected by manually drawn bounding boxes around them. This method (bounding box AlexNet = BA) still contained parts of surrounding structures which may have affected the automated stage allocation performance. We hypothesize that segmenting only the third molar could further improve the automated stage allocation performance. Therefore, the current study aimed to determine and validate the effect of lower third molar segmentations on automated tooth development staging. Retrospectively, 400 panoramic radiographs were collected, processed and segmented in three ways: bounding box (BB), rough (RS), and full (FS) tooth segmentation. A DenseNet201 CNN was used for automated stage allocation. Automated staging results were compared with reference stages – allocated by human observers – overall and per stage. FS rendered the best results with a stage allocation accuracy of 0.61, a mean absolute difference of 0.53 stages and a Cohen's linear κ of 0.84. Misallocated stages were mostly neighboring stages, and DenseNet201 rendered better results than AlexNet by increasing the percentage of correctly allocated stages by 3% (BA compared to BB). FS increased the percentage of correctly allocated stages by 7% compared to BB. In conclusion, full tooth segmentation and a DenseNet CNN optimize automated dental stage allocation for age estimation.     

New challenges for universities in the knowledge triangle

This paper discusses the role of higher education institutions within the framework of the knowledge triangle between academic education, scientific research and innovation, as it has gained importance in recent years as a framework for innovation policies especially in the OECD and Europe. First, complementary concepts of universities’ outreach activities and extended role model such as ‘third mission’, ‘triple helix’, ‘entrepreneurial or civic university’ models and ‘smart specialization’ are reflected against their fit with the concept of the knowledge triangle, also with respect to new requirements for university governance. Second, a new understanding of spillovers between public sectors research and the business sector according to knowledge triangle is presented.

     

The Paradox of Weakness in European Trade Policy: Contestation and Resilience in CETA and TTIP Negotiations

Over the last decade, trade negotiations with Canada and the United States met with considerable resistance from non-governmental organisations (NGO). Moreover, the negotiation mandates given to the European Commission were so broad as to include topics falling under so-called mixed competence of the EU and the member states, necessitating not only ratification by the EU Council of Ministers and the European Parliament, but also member states’ parliaments. At some point, these two factors almost seemed to paralyze the EU as a trade negotiator. In the end, however, the EU concluded an agreement with Canada, renegotiated its agreement with Mexico (while also concluding agreements with Singapore and Japan amongst others), while negotiations with the US were suspended. Three factors can account for this puzzling combination of apparent incapacity and blockage and surprising resilience of EU trade policymaking. First, the NGO contestation campaigns did not muster pan‐European but rather only varying degrees of support. Second, in addition to scrutiny by the European Parliament, consensus decision-making in the Council fosters accommodation of the demands of all member states. This leads to a low degree of negotiating autonomy on the part of the European Commission, yet large bargaining power for the European Union, as long as the other side wants agreement. Finally, a recent ruling by the Court of the EU facilitated the decoupling of agreements on portfolio investment and investment arbitration (one of the most difficult hurdles), from all other matters of trade and regulatory cooperation, making it easier to reach agreement.     

Irregular Maritime Immigration in the Canary Islands: Externalization and Communautarisation in the Social Construction of Borders

Analyzing irregular international migration requires a border concept that can be integrated into the social sciences and migration theories. This article views borders as social institutions and considers irregular migration patterns in the Canary Islands from the 1990s as resulting from changes in border management introduced by Spain and the European Union. After the peak of irregular maritime arrivals in 2006, a multilayered deterrence strategy was implemented through increased border surveillance and externalization measures such as readmission agreements and policing the borders of transit countries. As a result, the Atlantic route from Africa to Europe has lost its importance as an alternative to the Mediterranean corridor.     

Justifying Inequality as Equality: Germany and the Reform of Voting Weights in the Council of the European Union

ABSTRACT

Weighted voting institutionalises inequality in international organisations. How is it possible that states accept rules that formally privilege some over others even though this contradicts the sovereign equality of states and norms of democratic decision-making? This contribution to a special issue about global stratification shows that arguments about equality can actually serve to justify inequality in international institutions. This can be seen in moves by the German government to justify its proposals for a reform of voting in the Council of the European Union (1995–2008). Successive German governments focused on arguments about democracy based on the equality of states and of citizens to justify their push for a more privileged position for Germany in the Council. Efficiency also figured as a justification but was clearly less prominent.     

Coordination Risk and Cost Impacts on Economic Development in Poor Rural Areas

This paper addresses issues relevant to a critical problem in economic development: how to get rapid pro-poor economic growth in poor rural areas in Africa and South Asia where most of the world's dollar a day poor live. It examines constraints to the development of coordinated exchange systems in poor rural areas, focusing on the core problem of thin markets and low density of economic activity in these areas. Transaction cost and risk analysis is integrated into a conventional neoclassical production economics framework to describe the existence of low level equilibrium traps in transactions and supply chains and to generate important insights for development policy.     

German Arms Exports: Between Normative Aspirations and Political Reality

Deciding on arms exports is a delicate matter in western democracies. Potential economic and security gains have to be weighed against normative and security concerns. This article explores how this tension is solved in Germany, a country that holds strong moral aspirations but at the same time lists among the top arms exporting nations worldwide. Using a newly compiled dataset, we quantitatively analyse German exports of major conventional weapons (MCWs) from 1992 to 2013. Our statistical findings do not support the claim that the human rights situation in recipient countries plays an important role for German arms export decisions. Our two-stage model therefore supports a trading state rather than civilian power reading of Germany, at least when it comes to arms export practices.     

European security policy for the people? Public opinion and the EU's Common Foreign,Security and Defence policy

The democratic foundations of European integration in the foreign and defence realm are increasingly being debated. This article looks at the question of democratic legitimacy from one particular angle, by examining public opinion as measured in Eurobarometer surveys between 1989 and 2009. Based on reflections about the relation between polling results and wider questions of democracy, it examines three aspects of public opinion: general support for a common foreign and a common defence policy; differences among support rates in EU member states; and what roles Europeans would prefer for European armed forces. It turns out that general support for a common foreign policy is high, whereas the desirability of a common defence policy is much more contested. Moreover, citizens across Europe would prefer European armed forces to take on traditional tasks, as territorial defence. An EU defence policy that goes beyond strict intergovernmentalism and is directed towards protecting international law and universal human rights would thus require a significant communicative effort to become accepted.