The supermajority core of the US Senate and the failure to join the League of Nations

The failure of the United States to join the League of Nations is often considered to be an outcome of isolationist influence. The supermajority requirement of treaty ratification in the US Senate also is blamed for allowing a minority of isolationists to block the will of the majority that supported the treaty. To determine the cause of the failure, I analyze the Senate debate over the treaty using the concepts of the supermajority core and supermajority winset. Using all 157 votes on the treaty, I estimate senatorial positions and the locations of both the status quo and the treaty on the same metric space. From this analysis, I find that isolationists were not influential enough to block the ratification. Instead, President Wilson’s unwillingness to compromise is found to have played a critical role in the treaty’s defeat. The treaty’s defeat thus was not an indication of the power of isolationism. This study contributes to the growing body of literature that debunks claims about the dominance of isolationism in the interwar period. At the same time, the paper demonstrates how the core and winset concepts can be useful in answering substantive collective choice questions.     

Cracks in the Opposition: Immigration as a Wedge Issue for the Reagan Coalition

The absence of a core means that a majority coalition can never choose a policy that will keep it safe from minority appeals to its pivotal members. In two dimensions, strategic minorities will always be able to offer pivotal voters attractive policy concessions. We argue that this instability of multidimensional politics explains why minorities raise wedge issues and how wedge issues result in partisan realignment in legislative politics. Applying agenda‐constrained ideal point estimation techniques to immigration debates, we show that the Reagan coalition—pro‐business and social conservatives—has been vulnerable on the wedge issue of immigration and that parties have switched their positions on immigration over the last three decades. We use the uncovered set as the best‐fit theoretical solution concept in this legislative environment, to capture the limits of majority rule coalitional possibilities and policy change in the two‐dimensional absence of a core.     

Effect of Sex Offenders Treatment Program on Cognitive and Emotional Characteristics of Mentally Ill Sex Offenders

This study assessed the effect of a 10‐week cognitive behavior treatment program in 30 mentally ill sex offenders. The effect of the program was evaluated using the Interpersonal Responsiveness Index (IRI), UCLA Loneliness Scale (UCLALS), Coping Using Sex Inventory (CUSI), and Rape Myth Acceptance Scale (RMAS). Data were analyzed using the paired t‐test. The ability of sex offenders to cope with sexual acts when they faced stressful situations and to accept the rape myth was significantly improved on CUSI (t = 2.09, p = 0.04) and RMAS (t = 5.45, p < 0.001). Feelings of isolation and the ability to empathize based on IRI (t = 0.62, p = 0.54) and UCLALS (t = 0.88, p = 0.38) were not significantly improved. To prevent recidivism, treatment for mentally ill sex offenders should focus on changes in their cognitive and emotional characteristics in addition to their main psychiatric illness.     

DNA Typing for the Identification of Old Skeletal Remains from Korean War Victims*

Abstract: The identification of missing casualties of the Korean War (1950–1953) has been performed using mitochondrial DNA (mtDNA) profiles, but recent advances in DNA extraction techniques and approaches using smaller amplicons have significantly increased the possibility of obtaining DNA profiles from highly degraded skeletal remains. Therefore, 21 skeletal remains of Korean War victims and 24 samples from biological relatives of the supposed victims were selected based on circumstantial evidence and/or mtDNA‐matching results and were analyzed to confirm the alleged relationship. Cumulative likelihood ratios were obtained from autosomal short tandem repeat, Y‐chromosomal STR, and mtDNA‐genotyping results, and mainly confirmed the alleged relationship with values over 10⁵. The present analysis emphasizes the value of mini‐ and Y‐STR systems as well as an efficient DNA extraction method in DNA testing for the identification of old skeletal remains.     

Simple and highly effective DNA extraction methods from old skeletal remains using silica columns

The recovery of DNA data from old skeletal remains is often difficult due to degraded and very low yield of extracted DNA and the presence of PCR inhibitors. Herein, we compared several silica-based DNA extraction methods from artificially degraded DNA, DNA with PCR inhibitors and DNA from old skeletal remains using quantitative real-time PCR. We present a modified large-scale silica-based extraction combined with complete demineralization, that enables maximum DNA recovery and efficient elimination of PCR inhibitors. This is performed with high concentration of EDTA solution for demineralization of bone powder followed by QIAamp^® spin columns and buffers from the QIAquick^® PCR purification kit. We have successfully used this modified technique to perform STR analysis for 55-year-old skeletal remains. The results of this study will contribute to solve the forensic cases dealing with skeletal remains.     

Analysis of the impurities in the methamphetamine synthesized by three different methods from ephedrine and pseudoephedrine

Organic impurities of methamphetamine may show different patterns by synthesis. In the present study, we tried to find the impurities reflecting the conditions of synthesis by comparing impurity patterns of the methamphetamine samples synthesized by different methods. Sixteen methamphetamine samples were synthesized from ephedrine and pseudoephedrine by the three different manufacturing methods of Emde, Nagai and Moscow. The synthesized samples were extracted with ethyl acetate containing four internal standards, and the patterns of the organic impurities were investigated by GC-MS and GC-FID . Through the investigation, we found 10 peaks appearing in the latter part of GC chromatograms are characteristic to synthesis. The areas of the selected peaks were converted to the variables suitable for the statistical calculation, and the synthesized samples could be classified into four groups through the resultant cluster analysis.