Managing incidental findings in human subjects research: analysis and recommendations.

No consensus yet exists on how to handle incidental findings (IFs) in human subjects research. Yet empirical studies document IFs in a wide range of research studies, where IFs are findings beyond the aims of the study that are of potential health or reproductive importance to the individual research participant. This paper reports recommendations of a two-year project group funded by NIH to study how to manage IFs in genetic and genomic research, as well as imaging research. We conclude that researchers have an obligation to address the possibility of discovering IFs in their protocol and communications with the IRB, and in their consent forms and communications with research participants. Researchers should establish a pathway for handling IFs and communicate that to the IRB and research participants. We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed.     

Barack Obama Meets Celebrity Metaphor

Common knowledge suggests that elections are won or lost based on demographics, finances, and other structural elements. Whether candidates win or lose, however, is a matter of action. Symbolic identification, metaphor, and an unfolding narrative—and how they are managed and interpreted in the flow of events—determine who will emerge victorious from the democratic struggle for power. The McCain campaign’s effort to cast Obama as a celebrity, with the hollow trivialities and self-aggrandizement of Paris Hilton and Britney Spears, proves to be one of the most dangerous episodes for the Obama campaign. In response, the Democrats must adjust the staging of Obama’s Thursday night acceptance speech in Denver as a performance of purpose and gravitas, rather than glitz and adoration.