A fatal intoxication by chloroprene

Objective Chloroprene, 2-chloro-1,3 butadiene, is a volatile synthetic liquid. The chloroprene monomer is extremely reactive and is used for the production of latexes and synthetic rubber such as Neoprene. Up to now an acute lethal human exposure has been described only once in the literature [19]. The intoxication is associated with nervous system depression, pulmonary edema, narcosis, and respiratory arrest. Case report A 29-year-old chemistry company worker was found unconscious in an empty vessel (depth: 3m) used for chloroprene. The man was dressed in shoes, trousers, a helmet and a respiratory mask. The upper part of the body was unclothed. In spite of reanimation, the man died three hours later in a hospital. Material and methods: All analyses were performed by headspace gas chromatography (HS/GC/FID). In addition, brain, muscle and myocardial muscle were analysed by headspace GC-MS. Results and discussion Autopsy findings: The cause of death could not be determined as the macromorphological findings were unspecific. Toxicology findings The calibration curve of chloroprene in serum shows linearity from 1.0 to 200 μg/ml (r(2)=0.9999) using benzene as internal standard. The LOD is 0.28 μg/ml, the LLOQ is 0.99 μg/ml. Tissues and body fluids were stored at -20 °C till the analysis. Chloroprene was quantified after addition of benzene as the internal standard. It was found in nearly all tissues and body fluids except in the urine and lung. The highest concentrations were detected in the kidney, liver, myocardial muscle and especially in the brain. Furthermore, hexanal was found in all samples except in the urine. The amount of hexanal in some specimens is high, especially in the lung, bile, gastric content and myocardial muscle. Conclusion We assume that a significant amount of chloroprene was not only inhaled but also absorbed through the skin because the man wore a respiratory mask. Presumably the accident would not have happened if the works safety protocols had been followed. The reason why high concentrations of hexanal were found in the tissues could not be clarified.     

Assessing Callous-Unemotional traits across different groups of youths: further cross-cultural validation of the Inventory of Callous-Unemotional traits

The Inventory of Callous-Unemotional (CU) Traits (ICU) is a self-report questionnaire which was developed to measure the affective features of psychopathy in children and adolescents. Previous studies reported both support and difficulties with this promising new measure. The present study investigated the psychometric and discriminating qualities of the Dutch questionnaire across different groups by examining its structure, distribution and correlates. The ICU was administered to young clinical offenders (detained, N=127), healthy controls (community, N=172), non-clinical offenders (not detained, N=42) and an externalizing non-offender group (under treatment for behavioral problems, N=42). The age range for all groups was 13-20years. Since confirmatory factor analysis of models from earlier research did not yield an acceptable fit, exploratory factor analysis was conducted. Five factors were extracted: Lack of Conscience, Uncaring, Unemotional, Callousness and Lack of Empathy. The results indicated moderate to good test-retest stability and adequate internal consistency. CU traits correlated well with measures of conduct problems and aggression, indicating a good criterion and convergent validity. Results indicate weak associations with expert (Psychopathy Checklist: Youth Version, PCL:YV) and informant (Antisocial Process Screening Device, APSD) measures of psychopathic traits. Although groups could be differentiated on a statistical basis, no meaningful distinction based on CU traits alone was possible. Results of this study cast doubt on the validity of the current ICU. Suggestions are made for improvement.     

Suicide with a manipulated hand grenade

Explosion injuries in civilians are rare. An uncommon case of suicide with a manipulated hand grenade is presented. The findings at the scene and on the body (i.a. massive soot blackening of the skin, singeing, size and number of splinters) gave reason to doubt the use of trinitrotoluene (TNT), the usual explosive charge in hand grenades. Further investigations showed that parts of several hand grenades and black powder from standard fire-crackers commercially available without legal restriction had been used as propelling charge. The victim, who was in a sitting position, held the hand grenade in the left hand and triggered it with the right. He bled to death due to a fracture of the right femur and lacerations of the liver. The chronological course and total circumstances of the case suggested suicide in a strongly intoxicated condition (BAC 2.5 per mille). In the flat, a larger number of unlicensed weapons and weapon parts were found.     

Pretrial Publicity and Civil Cases: A Two-Way Street?

Published pretrial publicity (PTP) research has been conducted almost exclusively with criminal cases and has focused on PTP that is detrimental to the defense. The current research examined the effects of PTP in a civil case to determine if PTP can have a biasing effect against either the defendant or the plaintiff in civil litigation. In Experiment 1, participants exposed to PTP biased against the defendant were more likely to reach a liable verdict than participants who read a control article or PTP biased against the plaintiff. Experiment 2 demonstrated that a judicial admonition did not reduce the biasing effect of PTP about a civil defendant. However, participants given the admonition both before and after the trial evidence viewed the defendant as less culpable than participants given the admonition after the trial only or not at all. The implications for the legal system are discussed.     

Global Connections: ‘A Tool for Active Citizenship’

As a result of globalisation and changing technologies, young people are increasingly required to engage with the broader world beyond their local and national communities. This raises significant questions about the ways and spaces in which young people will need to engage as active citizens, and the new tools and resources that young people will need to equip them for their futures. The Global Connections Program has been developed to address these identified needs. It is a youth-led global learning initiative which aims to provide an opportunity for connection and learning among young people in Australia and Indonesia. This article explores Plan's youth-led approach to global learning, with a focus on the implementation and evaluation findings of the Global Connections Program, as well as the challenges faced thus far.     

Articulating Body,Territory, and the Defence of Life: The Politics of Strategic Equivalencing between Women in Anti-Mining Movements and the Feminist Movement in Peru

In Latin America, rural and indigenous women have mobilised in defence of their territories and built strategic alliances with urban and mestiza feminist movements. This paper focuses on how these processes have played out in Peru, tracing the development of the discourse on ‘body as territory’, which articulates sexual and reproductive rights with territorial autonomy. It discusses the ‘cosmopolitics’ of translating the distinct concerns and worldviews of the women involved, arguing that this discourse has enabled partial recognition and strategic equivalencing but that it has failed to fundamentally transform the underlying asymmetric relations of power and privilege.     

Austria's Report Card on Neutrality during the Hungarian Crisis of 1956

The Hungarian revolution of 1956 tested the Austrians' ability to exercise neutrality for the first time, while simultaneously rendering humanitarian aid to Hungarian refugees. Needing to justify the invasion of a Warsaw Pact ally, communist authorities exploited issues like border incidents, espionage, repatriation of refugees, and favouritism toward organisations to “prove” Austria's breech of neutrality. The Raab government — which signed the State Treaty only one year earlier — prudently weighed every move, passing the test admirably.