Aromatic content in medium range distillate products--Part I: an examination of various liquids

Classification of ignitable liquids in accordance with voluntary consensus-based standards published by ASTM International has become increasingly specific, relying upon both the chemical composition and the boiling point range of submitted ignitable liquids. This classification system includes among others, specific classes for distillates and dearomatized distillates. In this study, a variety of medium-range ignitable liquids were analyzed by gas chromatography-mass spectrometry. Several methods of data analysis were utilized to examine the relative aliphatic and aromatic contents in these liquids. Results show that commercially available products in the medium range exhibit a broad range of compositions with respect to the relative proportion of aliphatic and aromatic compounds and that some liquids may not be easily classified. This study demonstrates the importance of examining the proportion of aliphatics:aromatics for classifying such liquids and suggests guidelines for differentiating medium range distillates, dearomatized distillates, and blended products.     

Anorectic sibutramine detected in a Chinese herbal drug for weight loss

In the presented case, a young healthy woman had ordered a Chinese herbal medicine, called "LiDa Dai Dai Hua Jiao Nang", via internet. She took this product for approximately 1 week, but on the second day she developed severe headache, vertigo and sensation of numbness. After discontinuing medication, symptoms disappeared within 2 days. For identification of the ingredients, a urine sample as well as a sample of the "LiDa" capsule were analysed by GC-MS and HPLC-DAD. One major ingredient was detected in urine as well as in the "LiDa" capsule and was identified as sibutramine. Quantification by HPLC-DAD yielded 27.4 mg sibutramine base, which is approximately two times the amount of the highest authorized single dose available on the pharmaceutical market in Germany. This case demonstrates a common problem with herbal medicines, where adulterations with synthetic therapeutic substances can lead to severe side effects and/or potentially fatal interactions with conventional medicines.     

Survival of severe amlodipine intoxication due to medical intensive care

We report the case of attempted suicide with amlodipine, chlorthalidone and mefenamic acid and subsequent medical intensive care measures which resulted in total recovery of a 42-year-old male. After admission to the medical intensive care unit the intoxicated patient was deeply hypotensive and needed fluid replacement, dobutamine and norepinephrine. Additionally insulin and calcium gluconate were given. Since hypotension persisted and the patient developed oliguria, terlipressin was applied and finally showed an effect on blood pressure and on urinary output. A volume overload of 7 L in the first 24 h resulted in a pulmonary edema. The patient was started on non-invasive ventilation with continuous positive airway pressure (CPAP) and frusemide was added to the therapy with good success. Quantitative determination of amlodipine in plasma samples was performed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The highest amlodipine concentrations was measured in the plasma sample collected approximately 8 h after ingestion of the drug, and was 393 microg/L. Four days later, it was possible to stop the treatment with catecholamines, at that time the amlodipine plasma concentration had declined to 132 microg/L, still tenfold higher than therapeutic (5-18 microg/L). Elimination half-life of amlodipine is approximately 55 h. After 6 days in the intensive care unit the patient was transferred to psychiatric treatment. Intensive care management and plasma levels in this intoxication case are compared to data from literature on other cases.     

Bedroom rape: sequences of sexual behavior in stranger assaults

This article examines the sequential, temporal, and interactional aspects of sexual assaults using sequential analysis. Fourteen statements taken from victims of bedroom-based assaults were analyzed to provide a comprehensive account of the behavioral patterns of individuals in sexually charged conflict situations. The cases were found to vary in the sexual severity of assault, distinguishing a variety of motivations and behavioral repertoires of offender and victim. Two quite distinct styles of offense were identified: multiple and single, which may have very different implications for research into rapist taxonomies and rape prevention strategies.     

Sixth Graders’ Conflict Resolution in Role Plays with a Peer,Parent, and Teacher

This study used conflict resolution role play vignettes and self-report surveys of 450 New York City 6th graders to examine associations between adolescents’ conflict resolution efficacy and social skills. Vignettes covered 3 social contexts, conflict with a peer (disagreement over activities), with a parent (raise in allowance), and with a teacher (low grade on report). Effective and ineffective strategies for resolving these conflicts were coded from the videotaped interactions. Adolescents were more often effective in resolving conflict with peers than with parents (χ²(1) = 7.10, p < .01). Strong communication skills cut across interpersonal context as associated with effective resolution. Assertiveness and absence of aggression were associated with effective conflict resolution in vignettes with peers. Assertiveness was also associated with effective conflict resolution in vignettes with parents, however nervousness was unexpectedly found to facilitate conflict resolution in vignettes with parents. Only skills observed within a particular context were associated with effective resolution in that context; self-report skills and cross-context observed skills were not associated with efficacy. Implications for implementation and evaluation of social skills curricula and conflict resolution process are discussed.An earlier version of this paper was presented at the meetings of the Society for Research on Adolescence, New Orleans, LA, April 2002Received Ph.D. in Developmental Psychology from Teachers College, Columbia University in 2004. Research interests include adolescent social competence and youth development programs.Received Ph.D. in Developmental Psychology from Pennsylvania State University in 1991. Research interests include the psychosocial correlates of puberty, stress reactivity, and health compromising behaviors and adjustment.Received Ph.D. in Developmental Psychology from Teachers College, Columbia University in 2002. Research interests include social competence, prevention research, and women’s health.Received Ph.D. in Developmental Psychology from Teachers College, Columbia University in 2002. Research interests include social competence, prevention research, and women’s health.Received Ph.D. in 1975 from University of Pennsylvania in Human Learning and Development. Research focus centers around designing and evaluating interventions aimed at enhancing the wellbeing of children living in poverty and associated conditions. Conducts research on transitional periods during childhood and adolescence, focusing on school, family and biological transitions in childhood, adolescence, and adulthood. Specific interests are in the factors that contribute to positive and negative outcomes, and changes inwell-being over these years.Received Ph.D. in Developmental Psychology from Columbia University in 1977. Research interests include tobacco, alcohol, and drug abuse prevention, violence prevention, AIDS risk reduction among adolescents, health promotion and disease prevention, smoking cessation.     

Parent Perceptions of Participating in a Program for Adolescents Who Are Violent at Home

Child-to-parent abuse (CPA) is an under-addressed form of family violence and relatively few resources are available for families experiencing CPA. The Step-Up program is a CPA-specific, family-level, group format intervention program in King County, Washington. Qualitative and long-term research on CPA intervention programs is lacking, and it is unknown how parents perceive the effects of participating in Step-Up after program completion. Fifteen parents who completed Step-Up with their adolescent child participated in individual semi-structured telephone or in-person interviews. Participants were asked about their perceptions of the effects of Step-Up participation, how they and their child have used skills taught in the program, and which program features were most and least effective. Participants expressed largely positive effects of participating in Step-Up, including decreased violent behavior by their adolescents and improved parent-child relationships. Recommendations for improving Step-Up included the inclusion of follow-up sessions to further reinforce behavior change and increased program accessibility.