Raman Microspectroscopic Mapping: A Tool for Identification of Fused Materials in Fire Debris

Examination of fire debris can provide information about the types of materials which were present at the time of the fire to give insights for fire scene reconstruction and understanding compartment fire dynamics. This paper demonstrates the ability of Raman spectroscopy for material identification postfire in complex situations, such as the production of fused masses during fire dropdown. A validated Raman spectral library is combined with Raman mapping in three fire case studies, to determine the individual materials in the fused masses formed. The case studies accessed material combinations of several common polymers. Raman mapping was carried out on a 10 μm × 10 μm square of the masses. Material identification using this technique ranged from a high of 85% match to a low of 40% match. This work demonstrated that complex masses found in the fire debris can be resolved into the individual material components for identification and spatial distribution.     

Brexit and Parliamentary Sovereignty

This note addresses the implications of R (Miller) v Secretary of State for Exiting the European Union for the legal principle of parliamentary sovereignty, and argues that the strong restatement of the latter is the most significant feature of the decision. The aim here is to show how traditional principle in the Dicey tradition has been strongly applied against the competing claims of EU law, the royal prerogative, the referendum and devolution. However, the note also argues that the claims relating to parliamentary sovereignty could have produced a different result and that the most compelling feature of the case was the argument that was not forcefully put by the Government, namely that Parliament had already provided sufficient authority for the triggering of Article 50.     

Measuring Bias and Uncertainty in Ideal Point Estimates via the Parametric Bootstrap

Keith T. Poole Center for Advanced Study in the Behavioral Sciences and Department of Political Science, University of Houston, Houston, TX 77204-3011 e-mail: kpoole{at}uh.edu Over the last 15 years a large amount of scholarship in legislativepolitics has used NOMINATE or other similar methods to constructmeasures of legislators' ideological locations. These measuresare then used in subsequent analyses. Recent work in politicalmethodology has focused on the pitfalls of using such estimatesas variables in subsequent analysis without explicitly accountingfor their uncertainty and possible bias ( Herron and Shotts2003, Political Analysis 11:44–64). This presents a problemfor those employing NOMINATE scores because estimates of theirunconditional sampling uncertainty or bias have until now beenunavailable. In this paper, we present a method of forming unconditionalstandard error estimates and bias estimates for NOMINATE scoresusing the parametric bootstrap. Standard errors are estimatedfor the 90th U.S. Senate in two dimensions. Standard errorsof first–dimension placements are in the 0.03 to 0.08range. The results are compared with those obtained using theMarkov chain Monte Carlo estimator of Clinton et al. (2002,Stanford University Working Paper). We also show how the bootstrapcan be used to construct standard errors and confidence intervalsfor auxiliary quantities of interest such as ranks and the locationof the median senator.     

Self-reported suicidal behavior in juvenile offenders in custody: prevalence and associated factors

Suicide rates in prisons in England and Wales are high, including those in juvenile detention centers. Previous deliberate self-harm (DSH) is the strongest predictor of suicide in the general population. There is limited information on how many juvenile offenders (15 to 18 year-olds) have a history of DSH at the time of entering custody, or on factors associated with previous DSH. We aimed to determine the prevalence of previous DSH and suicidal ideation in a population of juvenile offenders in custody and to identify factors associated with DSH and suicidal ideation. Seven out of 45 subjects (15.6%) reported an act of DSH in the past. Twelve (26.6%) reported past suicidal ideation. Peer relationship difficulties and sexual abuse were significantly associated with DSH (p < 0.05). Other factors showed a trend toward being more common among those with DSH, but the premature ending of the project by the juvenile detention center prevented full investigation of the extent of DSH and associated factors. Nevertheless, the results indicated a much higher rate of DSH in this population than in young males in the community. A larger joint project with juvenile detention centers is required to confirm the extent of previous DSH at the time young offenders are admitted, and the associated risk factors, in order to assist prevention and intervention strategies.     

Economic and legal analysis of medical ethics

In the last decade, the antityrust authorities have stricken one after another of the ethical rules of professional societies. Underlying this pokicy is the widelyaccepted notion that ethics are simply devices designed by the professions to limit competition and thereby to benefit their pecuniary interests. The antitrust assault does not consider the longstanding, nearly universal consumer support for controls on the activities of certain professions. In this paper, the narrow view ofcompetition adopted by the courts is assailed. Focusing on the case ofrestrictions on interactions between physicians and other nonmedical health care providers, some procompetitive effects of medical ethics are analyzed. Generally, professional ethics can only change the form of competition but not eliminate it. A proper legal policy requires recognition of the consumer concern with the form of competition and therefore requires a careful balancing of the beneficial competitive effects against any attendant limits on intraprofessional competition.     

'Incidents' and foreign policy: A case study

Anglo-Russian relations during the period 1894-1914 were filled with incidents in large part stemming from the very different social and political frameworks of the two countries. The two countries had sharply differing traditions concerning individual liberty, freedom of the press and other such matters usually covered by the rubric of human rights. While the realities of great power politics forced the two countries to work together, it is not surprising that their collaboration was often marred by clashes of political and social sensibilities.     

A technocratic fix to the "legitimacy problem"? The Blair government and health care rationing in the United Kingdom

The work of the National Institute for Clinical Excellence, an agency which has recently been created by Tony Blair's Labour government to provide guidance on best clinical practice to the National Health Service, has generated considerable controversy in the United Kingdom. It has been argued that the role which the institute plays in appraising cost effectiveness, especially of expensive new health technologies, constitutes explicit, national rationing. Although the employment of scientific and evidence-based criteria as the basis of decisions might have been expected to secure legitimacy for the institute--even when its recommendations have the effect of denying access to a particular treatment--the reaction to much of its work so far indicates that this goal has not been fully achieved. While alterations to structure and procedure may be considered as possible means of addressing the agency's difficulties, such proposals are not without problems. Consequently, in the final analysis, the British example may serve as a demonstration that the inherently political nature of priority-setting in health care precludes any easy technocratic solution.     

Characterization of human control region sequences of the African American SWGDAM forensic mtDNA data set

The scientific working group on DNA analysis Methods (SWGDAM) mitochondrial DNA (mtDNA) population data set is used to infer the relative rarity of control region mtDNA profiles obtained from evidence samples and of profiles used for identification of missing persons. In this study, the African American haplogroup patterns in the SWGDAM data were analyzed in a phylogenetic context to determine relevant single nucleotide polymorphisms (SNPs) and to describe haplogroup distributions for Africans observed in these data sets. Over 200 SNPs (n=217) were observed in the African American data set (n=1148). These SNPs ranged from having 1-39 changes in the phylogenetic tree, with sites 152 and 16519 being the most variable. On average there were 5.8 changes for a character on the tree. The most variable sites (with 19 or more changes each) observed included 16093, 16129, 16189, 16311, 16362, 16519, 146, 150, 152, 189, and 195. These rapidly changing sites are consistent with other published analyses. Only 34 SNPs are needed to identify all clusters containing 10 or more individuals in the African American data set. The results show that the African American SWGDAM mtDNA data set contains variation consistent with that described in continental African populations. Thirteen of the 18 haplogroups previously observed in African populations were observed and include: L1a, L1b, L1c, L2a, L2b, L2c, L3b, L3d, L3e1, L3e2, L3e3, L3e4 and L3f. Haplogroup L2a is the most commonly observed cluster (18.8%) in the African American data set. The next most common haplogroups in the African American data set include the clusters L1c (11.0%), L1b (9.1%), L3e2 (9.0%) and L3b (8.1%). Approximately 8% of the haplogroups observed within African Americans were common in European Caucasians or East Asians; these were H (n=32), J (n=4), K (n=5), T (n=2), U5 (n=6), U6 (n=9 also known from North Africa), A (n=12), B (n=7), C (n=4), and M (n=16), respectively. The European Caucasian and East Asian haplogroups are expected due to admixture between individuals with recent ancestry in Western Eurasia and sub-Saharan Africa. The genetic characterization of these relevant data sets is fully consistent with other published mtDNA genetic variation. The sequence diversity observed in this data set makes it a valuable tool for forensic applications.