Postmortem molecular analysis in victims of sudden unexplained death

Among several conditions that can be responsible for sudden cardiac death (SCD), an important role is played by long QT syndrome (LQTS). LQTS is a congenital electric heart disease that can be asymptomatic or have very severe clinical manifestation, leading to cardiac arrest. In fact, the first manifestation of LQTS can be hyperkinetic ventricular arrhythmias. The presence of LQTS should be considered in all cases of SCD where autopsy is negative for anatomic and histopathological findings. In these cases, after an accurate anamnesis, a genetic screening should always be performed. The screening on LQTS genes is performed on DNA extracted from paraffin-embedded tissues. Making a proper diagnosis in such cases can help to find new affected subjects among the family members of SCD victims and treat them. In these cases, if the pathologist does not make a correct diagnosis, can he or she be sued for malpractice?     

Informal payments for health care: definitions, distinctions, and dilemmas

There is increasing interest in the issue of informal payments for health care in low- and middle-income countries. Emerging evidence suggests that the phenomenon is both diverse, including many variants from cash payments to in-kind contributions and from gift giving to informal charging, and widespread, reported from countries in at least three continents. However, cross-national research is hampered by the lack of consensus among researchers on the definition of informal payments, and the definitions that have been proposed are unable to incorporate all forms of the phenomenon that have been described so far. This article aims to overcome this limitation by proposing a new definition based on the concept of entitlement for services. First, the various forms of informal payment observed in practice are reviewed briefly. Then, some of the proposed definitions are discussed, pointing out that none of the distinctive characteristics implied by these definitions, including illegality, informality, and corruption, is adequate to capture all varieties of the phenomenon. Next, an alternative definition is formulated, which identifies the distinctive feature common to all forms of informal payments as something that is contributed in addition to the terms of entitlement. Then, the boundaries implied by this definition are explored and, finally, the implications for research and policy making are discussed with reference to the lessons developed countries can learn from the experiences of transitional countries.     

Economic concerns in Italian electoral behavior: Toward a rational electorate?

The current paradigm in the study of Italian electoral behavior finds in the ideological attachment and identification with political parties the basic determinants of voting. The relationship between economic conditions and electoral outcomes has not been the object of intense study, since it was assumed that the very predominance of the ideological dimension made any consideration of economic concerns among the electorate irrelevant. Recent research, employing both aggregate and survey data, shows, however, that economic conditions seem to exert an impact on electoral outcomes. Moreover, the emergence of a more rational and secular electorate might further increase the importance of economic voting.     

Neuropathological findings associated with retained lead shot pellets in a man surviving two months after a suicide attempt

We describe the neuropathological findings in a 30-year-old man who died two months after attempting suicide with a shotgun. We focused our study on lesions associated with retained lead shot pellets and distant therefrom, as well as lesions distant from the principal site of injury. At the sites of the retained lead shot pellets, we found macrophage proliferation and astrocyte activation, together with axonal spheroids and signs of neuronal damage. In the remaining white matter we observed axonal swellings, astrocyte activation and rarefaction of the neuropil; regressive phenomena of the neurons were also present. All axonal spheroids immunoreacted with antibodies against APP, alphaB-crystallin, NF subunits and ubiquitin. Most reactive astrocytes were positive for GFAP and alphaB-crystallin immunostaining. Some neurons immunoreacting with alphaB-crystallin were also found. These data indicated that an important local reaction developed at the sites of lead shot retention, and mild signs of diffuse axonal damage were found throughout the brain.     

Public Finance Issues and Problems in Switzerland

Switzerland is regarded as a bastion of financial conservatism, yet the Swiss federal government presently faces annual budget deficits of the highest magnitude in recent history. This article provides an overview of measures instituted in Switzerland to control the growth of the public sector and public spending. Recent efforts to raise new tax revenues are also discussed. To place the fiscal dilemma in perspective, an introduction to the structure of Swiss national government and the budgetary process is included. In analysis of Swiss budgetary politics, particular emphasis is given to the influence of the public referendum process on the political dynamics of resource decision making. The authors also analyze the area of the Swiss budget that is growing most rapidly—mandated entitlements—especially payments for unemployment compensation. A prolonged economic recession in Europe has created high unemployment and, consequently, high demand for unemployment compensation and other social "safety net" programs and spending. The most prominent feature of the Swiss political system is that it is headed by a stable coalition government in which leadership does not alternate between different political parties. This system confronts social and policy problems in a slow and deliberate manner due to the necessity for consultation and compromise in a multi-party coalitional government. The advantage of this system is stability and prudence, the disadvantage is perhaps short-term unresponsiveness to budgetary and policy dilemmas of the type now faced in Switzerland. Parallels are drawn between the Swiss budgetary problem and that faced by the U.S. executive and Congress.     

Sex Estimation from Human Cranium: Forensic and Anthropological Interest of Maxillary Sinus Volumes

Sex estimation is a key objective of forensic science. We aimed to establish whether maxillary sinus volumes (MSV) could assist in estimating an individual's sex. One hundred and three CT scans were included. MSV were determined using three‐dimensional reconstructions. Two observers performed three‐dimensional MSV reconstructions using the same methods. Intra‐ and interobserver reproducibility were statistically compared using the intraclass correlation coefficient (ICC) (α = 5%). Both intra‐ and interobserver reproducibility were perfect regarding MSV; both ICCs were 100%. There were no significant differences between right and left MSV (p = 0.083). No correlation was found between age and MSV (p > 0.05). We demonstrated the existence of sexual dimorphism in MSV (p < 0.001) and showed that MSV measurements gave a 68% rate of correct allocations to sex group. MSV measurements could be useful to support sex estimation in forensic medicine.     

Fatal Drowning Accident and Undiagnosed Hydrocephalus

Abstract: Bodies found in water present several diagnostic challenges for the forensic examiner, such as the identification of the time and mechanism of death, the postmortem submersion time, and above all the circumstances of drowning. We report the case of a 33‐year‐old security guard found dead in Venice, in the water of the lagoon, who at autopsy presented a previously undiagnosed hydrocephalus with macrocephaly. The victim remained asymptomatic until 2 months before death and had never undergone a neurological or radiological examination. In the article, we emphasize the need to perform a thorough autopsy in all suspected drownings, discuss the etiopathogenesis of the neurological disease and hypothesize a possible relationship between the hydrocephalus and the drowning accident. Finally, we discuss the major clinical and forensic implications of macrocephaly and hydrocephalus in adults.     

To execute or not to execute? Examining public support for capital punishment of sex offenders

In the 1990s, states enacted a plethora of new “get tough” laws targeting sex crime. These included extending the death penalty—a punishment typically reserved for murderers—to convicted sex offenders. Little attention, however, has been given to explaining why these tougher responses emerged and, in particular, whether the public supported extending the use of the death penalty to sex offenders. The goal of this paper was to examine whether public perceptions about executing sex offenders accorded with the punitive shift in policy and, more broadly, to contribute to scholarship on the death penalty. To this end, this paper examined data from a 1991 national public opinion poll, conducted just prior to the punitive shift in sex crime policies. The study found that views about executing sex offenders depended heavily on whether the victim was a child, that support for executing sex offenders was substantially lower than for executing murderers, and that few social and demographic divides differentially predicted support for executing sex offenders versus murderers. Implications of the study are discussed.     

Ten Years After Comparing Media Systems: What Have We Learned?

In this article we review research published since the publication of Comparing Media Systems which seeks to operationalize concepts discussed in that work and to test the framework proposed there or to put forward alternatives or revisions. We focus on works that deal with the original 18 countries covered in Comparing Media Systems, and consider the progress made in developing quantitative measures across these cases for key variables, research testing the grouping of cases in Comparing Media Systems, research extending the comparative analysis of Western media systems to new media, and research on convergence toward the Liberal Model. In the final section, we focus on limitations of the research produced during the 10 years following the publication of Comparing Media Systems, particularly the heavy emphasis on quantitative operationalization, and some of the difficulties in using quantitative analysis to investigate complex, dynamic systems.