Erroneous gender identification by the amelogenin sex test

Human gender identification, based on the amelogenin gene, has important applications in forensic casework, prenatal diagnosis, DNA databasing, and blood sample storage. However, we report on the first known case, in the Israeli population, of an amelogenin sex test failure on a phenotypically normal male. He was typed as a female by both the AmpFlSTR SGM plus and GenePrint kits. Subsequent, karyotyping of the soldier's blood sample showed no abnormalities. These results suggest that the determination of sex, based on the amelogenin test, should be interpreted cautiously.     

Developmental validation of a single-tube amplification of the 13 CODIS STR loci, D2S1338, D19S433, and amelogenin: the AmpFlSTR Identifiler PCR Amplification Kit

Analysis of length polymorphism at short tandem repeat (STR) loci utilizing the polymerase chain reaction (PCR) process has proven to be an ideal assay for human identification purposes. The short length of STR loci coupled with the amplification of target sequence through PCR allows for a robust, sensitive, and specific assay for highly polymorphic markers. A multiplex containing fifteen STR loci plus the gender-determining locus Amelogenin was developed to provide a single amplification/detection of all CODIS (Combined DNA Index System) STR loci (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, TH01, TPOX, and vWA) as well as two internationally-accepted STRs (D2S1338 and D19S433). By incorporating five-dye fragment analysis technology and non-nucleotide linkers, previously optimized AmpFlSTR kit primer sequences have been maintained. This kit has been developed in accordance with the standards of the forensic community as defined by the DNA Advisory Board. Validation studies were performed to include developmental validation, and the results support the use of the AmpFlSTR Identifiler PCR Amplification Kit for human identity and parentage testing.     

Public choice and tort reform

The common law originally was thought to be immune to rent seeking. More recently, scholars have recognized that attorneys are engaged in exactly that activity. Rent seeking by the legal profession has greatly expanded the scope of US tort law, and generated efforts to reverse its expansion. Organized groups (attorneys, businesses and doctors) are active on both sides of the issue and the partisans have numerous tools available for advancing their agendas, such as litigating, lobbying for favorable rules and attempting to elect sympathetic legislators and judges. All of this creates an ideal setting for public choice analysis.     

Participation in a national,means‐tested school voucher program

We use data from a sample of applicants to a national means‐tested school voucher program and a national sample of the population eligible for the program to evaluate the factors leading families to use school vouchers. Our analysis divides the process of voucher usage into two distinct stages: initial application and subsequent take‐up. Using a nested logit model, we find that some factors, like religious affiliation and religious service attendance, affect both stages. Others, like mother's education, affect only one (application). Still others, like ethnicity, have opposite effects at the two stages. Compared to Whites, minorities are more likely to apply for vouchers, but less likely to take them when given the opportunity. © 2005 by the Association for Public Policy Analysis and Management     

Territory, Contiguity, and International Conflict: Assessing a New Joint Explanation

Beginning with two prominent explanations of international conflict—one based on contiguity and the other on territory—I develop a new joint account that provides two important advancements over the prior explanations. I then test the expectations of this joint account on dispute and war onset for all dyad years from 1919 to 1995. I find strong support for its predictions at the dispute stage and partial support at the war stage, including marked evidence of contingency between contiguity and territory. The results also show territory to be a more consistent engine of conflict than contiguity, especially at the war onset stage. Further, the findings provide insights into the effects of contiguity among nonterritorial disagreements, as well as the effects of territorial strife among noncontiguous pairs. Thus, this investigation clarifies the relative importance of both territory and contiguity within any geography-based explanation of conflict behavior, and therefore has broadly interesting implications.     

Party Identification and Core Political Values

Party identification and core political values are central elements in the political belief systems of ordinary citizens. Are these predispositions related to one another? Does party identification influence core political values or are partisan identities grounded in such values? This article draws upon theoretical works on partisan information processing and value‐based reasoning to derive competing hypotheses about whether partisanship shapes political values or political values shape partisanship. The hypotheses are tested by using structural equation modeling techniques to estimate dynamic models of attitude stability and constraint with data from the 1992–94–96 National Election Study panel survey. The analyses reveal that partisan identities are more stable than the principles of equal opportunity, limited government, traditional family values, and moral tolerance; party identification constrains equal opportunity, limited government, and moral tolerance; and these political values do not constrain party identification.