Reversing microcrystalline tests--an analytical approach to recycling of microcrystals from drugs of abuse

A combined analysis of microcrystalline tests followed by LC-MS or GC-MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was done to quantify the recovery of the drug. Examples were performed using the date rape drug γ-hydroxybutyrate (GHB) and the synthetic opioid methadone.     

The Condorcet jury theorem and extension of?the?franchise with rationally ignorant voters

The Condorcet Jury Theorem (CJT), which provides a justification for democracy, is based on voters who are imperfectly informed insofar as they know the correct policy with a probability of less than one but greater than one-half. We reassess the consequences of the CJT for democracy when extension of the franchise adds equal numbers of non-distinguishable informed and uninformed voters to the collective decision making group. Uninformed voters vote correctly with probability one-half. We show that adding equal numbers of informed and uninformed voters maintains the CJT conclusion that enlarging the group of decision makers increases the likelihood of a correct collective decision.     

Bint al-Shati's Wives of the Prophet: Feminist or Feminine?

The Egyptian writer and Islamic scholar Dr. ^cA'isha ^cAbd al-Rahman (b. 1913), who originated from the countryside, was a pioneering woman in many respects, although she did not consider herself to be a feminist. She was one of the first Egyptians to write about the agrarian problems of the country and the plight of the peasants; and of the pioneering generation of female Arab literati. She was also the first Muslim woman to undertake Quranic exegesis. Writing under her pen name, Bint al-Shati', she was also one of the first women to deal with the life of the Prophet Muhammad through vignettes of the women in his life. Like many other modern Muslim biographers of the Prophet, she rendered classical Islamic materials in a new style. Although her book on the Wives of the Prophet often portrays women in a negative light, content analysis indicates that the work also reflects feminist themes.     

Effect of evaporation and matrix interferences on the association of simulated ignitable liquid residues to the corresponding liquid standard

Identification of an ignitable liquid in fire debris evidence can be complicated due to evaporation of the liquid, matrix interferences, and thermal degradation of both the liquid and the matrix. In this research, liquids extracted from simulated fire debris were compared to the original liquid using multivariate statistical procedures. Neat and evaporated gasoline and kerosene standards were spiked onto nylon carpet, which was subsequently burned. The ignitable liquid residues were extracted using a passive headspace procedure and analyzed by gas chromatography-mass spectrometry. Pearson product moment correlation coefficients, hierarchical cluster analysis, and principal components analysis were used to compare the liquids extracted from the carpet to the corresponding neat liquid. For each procedure, association of the extracts according to liquid type was possible, albeit not necessarily to the specific evaporation level. Of the three procedures investigated, principal components analysis offered the most promise since contributions from matrix interferences were essentially eliminated.     

The Riddle of Charisma

The word “charisma” is widely and carelessly employed, without investigation or definition of the phenomenon. Rather than a singular attribute, charisma is complex, manifesting itself in at least three non-exclusive forms: innate charisma, achieved charisma, and the charisma of position. Given the human craving for leadership, understanding the different forms of charisma and their associated strengths and weaknesses helps us steer between, triumph, tragedy and travesty.     

Political Sophistication and Vote Intention Switching: The Timing of Electoral Volatility in the 2009 German Election Campaign

This article investigates the link between political sophistication and electoral volatility. Showing that there is disagreement in the literature on whether switching party preferences is related to low or high levels of political sophistication, it is then argued that the effect of sophistication on vote switching might differ depending on when switching is measured. The effect of timing on volatility is investigated by means of the Short-term panel of the 2009 German Longitudinal Election Study. Results indicate that timing indeed matters, while sophistication increases the probability of switching parties before the campaign, the effect of political sophistication becomes more negative as Election Day draws near.     

Fatal intravenous fentanyl abuse: four cases involving extraction of fentanyl from transdermal patches

The transdermal fentanyl system delivers a specific dose at a constant rate. Even after the prescribed application time has elapsed, enough fentanyl remains within a patch to provide a potentially lethal dose. Death due to the intravenous injection of fentanyl extracted from transdermal patches has not been previously reported. We present 4 cases in which the source of fentanyl was transdermal patches and was injected. In all of these cases, the victim was a white male who died at home. Case 1 was a 35-year-old with no known history of drug use, who was found by his wife on the floor of his workshop. Police recovered a fentanyl patch, needle, and syringe at the scene. Case 2 was a 38-year-old with a known history of drug use whose family claimed that he was in a treatment program that used fentanyl patches for unknown reasons. His brother found him dead in bed, and law enforcement officers found a hypodermic needle beside the body; a ligature around his left hand, and apparent needle marks between his first and second digits were also noted. Case 3 was a 42-year-old with a recent attempted suicide via overdose who was found dead at his home. An empty box of fentanyl patches, Valium, Ritalin, and 2 syringes were found at the scene. Case 4 was a 39-year-old found by his mother, who admitted to removing a needle with attached syringe from the decedent's arm. Medications at the scene included hydrocodone, alprazolam, zolpidem, and fentanyl patches. All reported deaths were attributed to fentanyl intoxication, with blood concentrations ranging from 5 to 27 microg/L.