阳离子脂质体包裹CpG对猪瘟猪肺疫猪丹毒三联疫苗免疫效应的影响

对 3组分别注射猪瘟猪肺疫猪丹毒三联疫苗 (简称三联疫苗 )、CpG +三联疫苗、阳离子脂质体包裹CpG +三联疫苗的小鼠细胞和体液免疫反应进行了比较分析。结果显示 ,阳离子脂质体包裹CpG +三联疫苗免疫小鼠脾细胞增殖反应明显增强 ,白细胞介素 2 (IL 2 )诱生活性和免疫细胞数量、血液IgG含量较仅注射三联疫苗的小鼠显著增加。说明阳离子脂质体包裹CpG能增强小鼠对三联疫苗的体液和细胞免疫应答反应 ,使疫苗的免疫原性增强     

A “Declining“ Power and Its Countermeasures

The Iraq war and anti-terrorism became major topics during this year‘s presidential campaign in the United States. Heated debates over the two issues as well as long-term and unusually fixed “strict half-and-half“ division of U.S. media and society also caused by the two issues, to a great extent, have deeply revealed the changes of America‘s power status in world politics. ……     

中国共产党执政价值观探析

中国共产党在实现执政价值目标的过程中,需要正确认识和处理维护党的整体利益与代表人民的根本利益、实现党的最高纲领与践行党的最低纲领、完善党的执政方式与提高党的执政能力等重大关系;中国共产党的执政价值标准是一个具有多维量度的价值评判体系,其中党的执政基础的合法性、执政活动的有效性和执政行为的规范性,是评判党的执政价值的三个最为重要的量度;“科学执政、民主执政、依法执政”的执政方式,是中国共产党经过执政实践的长期探索和执政经验的科学总结,而形成的以党的执政价值目标为取向、执政价值标准为依归的执政价值模式。     

Elected leaders and collective land: Farmers’ evaluation of village leaders’ performance in rural China

Previous studies on village elections have focused on the election process, but few have examined post-election outcomes related to local land management systems. Land is the most important resource in Chinese villages, but land management and reallocation are the chief responsibility for elected village leaders. Previous studies show that villager attitudes toward the “fairness” of land reallocations and the type of village elections vary across villages. Some villages have an open election/nomination process while other villages have “closed” or unfair elections. We found that openly elected leaders are more accountable to villagers and that their land management decisions do reflect villager preferences for “fair” land reallocation. Our findings are based on a 2000–2001 survey of 34 villages in rural Shaanxi province. Rozelle is also a member of the Giannini Foundation of Agricultural Economics. We acknowledge the finical support of the Fulbright Fellowship and the University of California, Pacific Rim Research Fellowship. We want to thank the three anonymous reviews as well as Kevin O’Brien and Li Lianjiang for their comments and suggestions. In addition, we want to thank our friends and colleagues at Northwest University, Xian for all their help, collaboration and support. This paper was first presented in Chinese at the “Contemporary Rural Chinese Social Life” conference held at Hong Kong Polytechnic University November 21^st and 22^nd 2002.     

对我国建国初期多党合作制的回顾与思考

建国初期中国共产党领导的多党合作制的实行是由中国的历史和现实条件决定的。由于认识到这一点 ,也由于认识到实行包括多党合作制在内的民主建设是使中共跳出“历史周期律”和实现国家繁荣昌盛的重要手段 ,中国共产党在建国初期尽心尽力搞好多党合作制的建设。然而 ,由于当时对多党合作制的思想认识不足以及政治体制上存在的一些问题的影响等原因 ,使得本来发展势头良好的多党合作制在 195 7年后遭受挫折     

论公共行政变革与行政行为理论的完善

为了适应社会发展与公共行政变革的需要,有必要改造我国的行政行为理论,重新认识行政行为的特征,扩展行政行为的范围,将多种行政方式纳入行政行为体系中来,研究其运行的规则与应遵循的原则,促进行政法学与行政法治的发展。     

瑞金六大红色建筑设计者赵宝成沉冤始末

历经七十年风雨沧桑,瑞金六大红色建筑风物犹在,而工程建设者赵宝成却背负沉冤战死沙场……     

大蒜新素对MCMV感染小鼠脾细胞Th1/Th2类细胞因子水平的影响

目的:探讨大蒜新素对鼠巨细胞病毒(MCMV)感染小鼠脾细胞Th1/Th2类细胞因子水平的影响及其抗MCMV作用机制.方法:复制小鼠巨细胞病毒感染模型,将模型小鼠随机分成大蒜新素治疗组和安慰剂组,于MCMV感染后48 h开始分别给予大蒜新素一般剂量(25 mg·kg-1/d)和等量9.0 g/L氯化钠注射液腹腔注射;另设大蒜新素处理组和空白对照组,不接种病毒,分别给予大蒜新素一般剂量(25 mg·kg-1/d)和等量9.0 g/L氯化钠注射液腹腔注射.用ELISA法检测小鼠脾细胞Th1类细胞因子IL-2、IFNγ和Th2类细胞因子IL-4,IL-10水平.结果:MCMV感染可导致BALB/c小鼠Th1类细胞因子IL-2表达明显下降(P《0.01),Th2类细胞因子IL-10表达显著增高(P《0.01).大蒜新素能诱导正常BALB/c小鼠和MCMV感染模型鼠脾细胞Th1类细胞因子IL-2和IFNγ的表达显著增加(P《0.01),Th2类细胞因子IL-10表达明显下降(P《0.01).结论:大蒜新素能显著上调正常和MCMV感染模型小鼠脾细胞 Th1类细胞因子IL-2和IFNγ的表达,并抑制Th2类细胞因子IL-10的表达,通过诱导和促进特异性Th1优势应答反应来发挥抗CMV效应.     

波斯纳法律经济分析学说述评

波斯纳法律经济分析学说坚持效益应当被看做是法律的基本价值,它的效益理论的价值和经济分析方法是法学理论领域的重大突破。这个学说在我国市场经济条件下有特别重要的意义。     

口蹄疫病毒真核表达质粒的构建及序列分析

根据定点突变的原理 ,获得包含有口蹄疫病毒P1、2A、3C及部分 2B编码区的目的基因片段 ,经KpnⅠ和XbaⅠ双酶切后 ,与经同样处理的真核表达质粒载体 pcDNA3.1(+ )连接。经鉴定及DNA序列分析 ,口蹄疫病毒目的基因片段已被正确克隆到真核表达质粒载体pcDNA3.1(+ )上 ,且目的基因上的XbaⅠ位点成功突变