Hair as a specimen to document tetramethylene disulfotetramine exposure

Tetramethylene disulfotetramine (tetramine) is a rodenticide that has been banned for many years in China. Since 2005, inhabitants of a village in the Henan Province have been suffering from grand mal seizures. To investigate the possibility of tetramine as the cause, we developed a method to determine tetramine in human hair. Sample preparation involved external decontamination, frozen pulverization, and ultrasonication in 2 mL ethyl acetate in the presence of cocaine-d3 as an internal standard. The method exhibited good linearity; calibration curve was linear over a range of 0.1-20 ng/mg hair. The limit of detection for the assay was 0.05 ng/mg hair. Except for one subject (No. 4), all head and pubic hair samples were positive for tetramine. The concentrations of tetramine in pubic hair were significantly higher than those in the same subjects' head hair samples. Because of a long retention in body, segmental head hair analysis cannot provide an accurate exposure history of tetramine in the body.     

Validation studies of the ParaDNA® Intelligence System with artificial evidence items

Short tandem repeat (STR) profiling is one of the mostly used systems for forensic applications. In certain circumstances, STR profiling is time-consuming and costly, which potentially leads to delays in criminal investigations. LGC (Laboratory of the Government Chemist, UK) Forensics has developed a robust STR profiling platform called the ParaDNA^® Intelligence Test System which can provide early tactical intelligence and aid investigators in making informed decisions on sample prioritization for detection. Here, we validated the ParaDNA intelligence test for its application in forensic cases using a range of mock evidence items following guidelines set by the Scientific Working Group on DNA Analysis Methods (SWGDAM). Specifically, we tested the sensitivity and accuracy of the ParaDNA intelligence test, as well as the success rates for detecting mock samples and for use in case scenarios. Our findings demonstrate that the ParaDNA intelligence test generates useful DNA profiles, especially for samples such as blood, saliva, and semen that contain ample DNA, indicating the benefits of including ParaDNA as a prior step in forensic STR profiling pipelines.     

现代民事诉讼义务体系的构建——以法官与当事人在事实阐明上的责任承担为中心

根据法官与当事人在事实阐明方面的责任分配,各国典型的民事审理模式可分为三类:德国的对话诉讼、美国的对抗诉讼以及日本的对抗与判定模式。相较而言,德国的对话诉讼模式在辩论主义的框架内强调法官承担实质指挥诉讼的义务,彰显了诉讼集中主义,代表了现代民事诉讼的发展潮流。我国虽然历来注重法官的主动角色,但在从职权探知主义转向辩论主义的过程中如何设定法官在事实阐明方面的协助责任,还需深入探讨。同时,未来是否引入当事人的协助阐明义务、促进诉讼义务、真实完整义务和诚实信用义务,也关乎自认、举证期限等制度的完善以及恶意诉讼的克服。唯有构建起完善的诉讼义务体系,才能确保审理程序以公平、集中、快捷的方式进行。     

警察:请尊重公民的私权

公权与私权,是法制社会权利之两翼。现代法治设计的重要思想就是对公共权力的制约和对社会个体权利的保障。树立尊重公民私权的意识和遵守法定程序的观念,是我国人民警察队伍走向现代化的重要标志。     

论美国公共服务改革及其理论的新发展

美国公共服务改革是在特定的历史背景下,以“有限政府”理论、“企业化政府”理论和放松规制理论指导下进行的以民营化为手段,以顾客为导向,以竞争促效率的政府重塑运动。虽然成绩显赫,但新公共服务理论的出现,使我们对20多年公共服务改革核心价值进行更多的反思。     

360度职业生涯规划法建立及其在实践中的应用

360度职业生涯咨询法建立在近10万余名测评者和400余名面对面职业咨询的基础上,在大量的咨询实践中不断总结发展而来。该方法由理论基础、四层架构、应用模式等构成,综合运用了人才测评、管理学、心理学等学科知识,是一种全方位、个性化、面对面的职业生涯规划方法。     

构建基层公安民警大练兵长效机制的实践与思考——以杭州市公安局余杭区分局为例

杭州市公安局余杭区分局在大练兵活动过程中,抓住“练不练”、“练什么”、“怎么练”、“长期练”四个环节,扎扎实实地开展以警务实战技能为重点的大练兵活动,初步形成了岗位练兵、自学自练和集中轮训相结合的“三位一体”的练兵体系,取得了较好成效。大练兵活动关键是要建立长效机制,主要应包括:一、建立、完善大练兵组织领导机制。二、建立完善大练兵工作运行机制。三、建立完善大练兵考评、考核机制。四、建立完善大练兵保障机制。五、建立完善大练兵激励机制。     

贵州民族地区农村中小学数学教师专业化发展对策研究

本文应用调查法、访谈法、文献法等研究方法,对贵州民族地区农村中小学数学教师专业发展进行了调查研究。在深入调查现状的基础上,制定出符合该地区实际的对策:高等院校的引领;开展校本研究;充分发挥数学教研组在的作用;养成质疑反思的习惯;加大对教师的队伍建设和考核力度;发展民族地区农村现代远程教育等。     

论法制教育课程化与法制课程生活化

中学生在学习法律常识内容时普遍表现冷淡,但调查显示学生对开设法制教育课程的态度是肯定的,不满意的是法制教育的方式和手段。学校法制教育不是一般的法制宣传,它必须遵循教育规律,必须按照学校教育的特点将它设计成为合乎教育要求并服务于学校办学目标的学校教学课程,实现法制教育的“课程化”和“生活化”。     

团结就是力量 合作才能共赢

四月三亚,海风和畅,金砖国家领导人聚首于此,以＂展望未来、共享繁荣＂为主题,共商发展合作大计,开始了金砖国家新的扬帆启航;世界的目光聚焦于此,探究金砖国家的未来发展及其对国际格局的影响。十年前,当＂金砖四国＂还是高盛经济学家吉姆·奥尼尔提出的引导市场投资的虚拟概念时,有人提出疑问：＂要让这四块金砖粘在一起需要多少吨灰浆？＂