加强青年社团建设,推动社会发展

上世纪80年代以来,随着改革开放的不断深入,我国社会各个方面发生了巨大变化,进入了传统社会向现代社会转型的加速期,原来整体性的利益结构被打破,逐渐分化出不同的阶层,社会结构多元化、立体化.不同的社会阶层利用日益丰富的社会资源表达和维护自己的利益,不断推动民间社会的联合和组织化,社团的兴起和发展成为一种必然.     

当代中国大众文化发展的新思考

20世纪90年代以来,中国大众文化得到了迅猛发展,它对于当代中国文化发展具有双重影响：一方面,它促进了文化繁荣,丰富了人们的文化生活,推动了文化大众化进程。另一方面,它也产生了很多消极影响,对主导文化及其价值观产生了一定的冲击。我们必须加强对大众文化的管理,实现主导文化、精英文化与大众文化的良性互动,以社会主义核心价值体系引领大众文化的健康发展。     

环境管制与投资保护的法律冲突与协调

晚近以来，随着经济发展而不断提高的投资保护水平，成为了投资者对抗东道国公共管理权的利器，以致环境管制与投资保护之冲突时常见诸报端，并有愈演愈烈之势，东道国往往须就其环境管制行为向外国投资者支付巨额补偿，这引发了普遍忧虑。我们通过以环境管制引起的国际投资争议为焦点，拟从NAFTA条文本身和仲裁实践两个角度探究其处理环境管制与投资保护冲突的经验和教训，考察现有框架并预测未来规范之发展趋势，提出可行建议以资我国借鉴。     

世界经济发展不平衡加剧与中国经济的制度创新

过去 10年来 ,经济全球化的步伐在加快 ,世界经济发展的不平衡也在加剧 ,这是在世界范围内生产力与生产关系矛盾运动的必然规律和偶然事变综合作用的结果。世界经济发展史表明 ,不平衡发展是挑战 ,但更是后进者加快发展、实现崛起的机遇。中国是世界上最大的发展中国家 ,能否以入世为契机融入世界经济发展的主流 ,实现经济崛起 ,主要取决于经济制度的创新。     

Immunohistochemical distribution of C-reactive protein in the hepatic tissue in forensic autopsy

Previously, we examined the expression of C-reactive protein (CRP) in hepatic tissues in fatal injuries (injury deaths) immunohistochemically, and classified the CRP distribution into three patterns: diffuse (D-) pattern, diffuse with strong positivity in the hepatic lobules; periportal (PP-) pattern, characterized by positive cells in the periportal region of some lobules; focal (F-) pattern, showing small islands of positive cells in some lobules. There was a relationship between the CRP distribution and the survival time. In this study, we further analyzed the deaths including those due to other than fatal injuries (non-injury deaths), and a study of a total of 314 deaths from various causes was performed. Generally, non-injury deaths showed findings similar to those in injury deaths. PP- and/or F-patterns were observed in 43.7% of cases having a short survival time (<6 h), but found in only 3% of those surviving longer (>6 h), showing that such findings are suggestive of a short survival time. D-pattern was found more frequently in non-acute deaths (60.4%), than in acute deaths (10.9%). In acute deaths, D-pattern was found in some cases showing extensive tissue injuries, such as burns and polytrauma, and inflammative predisposition. Immunohistochemical findings also showed some correlation with the serum CRP level. Our data suggest that hepatic CRP immunohistochemistry may be a useful tool for elucidating the dying process.     

Pulmonary surfactant-associated protein A levels in cadaveric sera with reference to the cause of death

Pulmonary surfactant-associated protein A (SP-A) is an exclusively lung specific protein, and is considered to leak into the blood stream in alveolar septal damage. In this study we examined the serum SP-A level in forensic autopsy materials using an enzyme immunoassay with monoclonal antibodies to assess the postmortem level in relation to the cause and mode of death. Although a gradual postmortem degradation should be taken into consideration, topological relationship of serum level seemed to be fairly stable (arterial> or =venous blood in most cases), indicating no evident influence of postmortem diffusion. Significant elevation of serum SP-A (76.7-250 ng/ml in left heart blood) was observed in hyaline membrane diseases from various causes independent of the postmortem intervals (<30 h). However, mean SP-A levels in postmortem heart blood were usually low in asphyxia including hanging, strangulation and choking (left, 25.5 ng/ml; right, 22.3 ng/ml), polytrauma (left, 13.1 ng/ml; right, 9.0 ng/ml) and stab wound to the neck (left, 34.1 ng/ml; right, 29.4 ng/ml). Prominent elevation was noted in a case of fatal strangulation with complication of idiopathic interstitial pneumonia, and also in some deaths due to drowning, burns in fires, blunt and gunshot chest injuries. These findings indicated that postmortem elevation of serum SP-A levels was associated with alveolar septal damage due to inflammation, mechanical and physical stresses, which caused leakage of SP-A into the bloodstream.     

大鼠心肌早期缺血内皮素的表达

为探讨心肌缺血后内皮素在心肌组织内表达的变化。用免疫组化SABC法研究内皮素的表达情况。结果发现缺血60min后 ,缺血区心肌细胞呈局灶性阳性 ;缺血120min后 ,血管平滑肌、内皮细胞及心肌细胞浆均呈阳性着色。对照和缺血30min组心肌组织未见有阳性反应。上述各组HE染色未见明显病理改变。     

血液中丙泊酚的GC-MS分析

目的应用气质联用仪(GC-MS),建立快速、灵敏地分析血液中丙泊酚的定性定量方法。方法血液1mL,加入内标,采用液液提取方法处理,GC-MS选择离子(SIM)模式测定。结果在0.1～10μg/mL范围呈良好的线性关系,相关系数R2为0.9931,最低检测限(LOD)为0.05μg/mL。结论所建立的方法简便、快速、特异性强、灵敏度高,可满足法庭毒物分析和临床毒物分析的需要。     

急性及己中毒的实验病理学研究

目的探讨及己对小鼠毒性作用的病理变化及其毒作用机制。方法应用及己水煎液对小鼠经口急性染毒,进行组织病理学观察血清生化、凝血机能检测。结果及己对小鼠的半数致死量(LD50)为41.12g/kg;染毒小鼠血清ALT和BUN升高;血液血小板计数减少、凝血时间延长;肝、脾、肾器官系数增大;肝、肾、心肌细胞变性、坏死明显,全身诸多器官淤血、出血性改变。结论及己毒作用的主要靶器官或靶组织是肝脏、肾脏、心脏和全身血管。毒作用机制是对线粒体、内质网等膜性结构及体内凝血机制的破坏。