Human Y-specific STR haplotypes in a Slovenian population sample

The allele distribution of the systems DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385 and YCAII were investigated in a sample of 121 unrelated males from Slovenia     

Allele frequencies for nine STR loci in Beijing Chinese

Allele frequencies for nine STR loci namely, D3S1358, HUMvWA, HUMFIBRA/FGA, D8S1179, D21S11, D18S51, D5S818, D13S317 and D7S820 were obtained from a sample of 198 unrelated Chinese in Beijing, China.     

STR data for the AmpFlSTR SGM Plus loci from Warmia and Mazury (NE Poland)

Allele frequencies for the ten STRs included in the AmpFlSTR SGM Plus kit were determined in a sample of 320 unrelated individuals born in the region of Warmia and Mazury (NE Poland). All loci met Hardy-Weinberg expectations. Exact tests disequilibrium analysis revealed only one departure from independence out of 45 pair-wise comparisons of the 10 loci.     

A fatal overdose of the ergot derivative cabergoline

A 79-year-old woman, with Parkinson's disease treated with cabergoline, was admitted to a hospital due to jaundice and weakness. She was found confused, absent minded, and died after 2 weeks. Autopsy showed an extrahepatic bile duct adenocarcinoma with spread to the gall bladder, the liver, and regional lymphnodes. While cleaning the hospital bed after her death, the nurses found several tablets hidden in the bed. Biological samples obtained at the autopsy were screened for common drugs and narcotics. Several drugs such as buprenorphine, codeine, paracetamol, and propranolol were detected in the blood at therapeutic levels. A method to determine cabergoline in whole blood and other forensic matrices was developed, and further investigations determined cabergoline concentrations in whole blood and liver tissue of 94 and 3100 microg/kg, respectively. The blood concentration was 100 times above the therapeutic level reported on cabergoline in plasma and in combination with her symptoms, suggest she took a fatal overdose of cabergoline.     

Computer aided shot reconstructions by means of individualized animated three-dimensional victim models

In cases of lethal firearm injuries with indefinite indications concerning self-versus third-party infliction a computer enhanced reconstruction with the aim of an anatomical feasibility study can provide significant clues concerning the course of the traumatic event.To this end an exact three-dimensional geometrical model of the victim including all relevant anatomical data as well as the careful documentation of the injuries and a three-dimensional model of the characteristic outlines of the weapon true to scale is generated with the help of an animation program (POSER Version 4, Meta Creation, Egisys AG).With this animated digital three-dimensional model of the victim and the weapon a series of simulation sequences is created by variation of the body positions and the grasp of the weapon. Anatomically impossible positions in view of the physical characteristics of the victim and the site and direction of the bullet path are automatically excluded from the reconstruction. An exact match of the simulation sequence and the real injuries is a statement for a possible self-infliction of the gunshot wound.     

Identification of impurities and statistical classification of methamphetamine tablets (Ya-Ba) seized in Thailand

Impurity profiles of methamphetamine tablets seized in Thailand have been investigated. The samples are extracted with small amounts of ethyl acetate under alkaline condition and the extracts are analyzed by capillary gas chromatography. Nine compounds (1,2-dimethyl-3-phenylaziridine, ephedrine, methylephedrine, N-formylmethamphetamine, N-acetylmethamphetamine, N-formylephedrine, N-acetylephedrine, N,O-diacetylephedrie, methamphetamine dimer) are identified as impurities in methamphetamine tablet. Caffeine and ethyl vanillin are also detected as diluents and/or adulterants, and acetylcodeine monoacetylmorphine and diacetylmorphine are contained in many samples. In addition, trans-3,4-dimethyl-5-phenyl-2-oxazolidone is newly found as an impurity. For characterization and comparison of methamphetamine tablet exhibits, intensely and commonly detectable nine peaks are selected as the factor for multivariate analysis. The procedures reported here permit classification of 250 analyzed exhibits into five groups and characterization of classified groups.     

Deduction of paternity index from DNA mixture

Determination of individual genotypes in DNA mixture remains a challenge in forensic science. Using an approach of mixture of distributions, this article provides formula for calculation of paternity index (PI) in cases where only tissue mixture of the mother and alleged father, the genotypes of the mother and child, but not that of the alleged father are available. The formula has been used to solve a real case using mother's vaginal tissue contaminated with semen from alleged father.     

Implications for DNA identification arising from an analysis of Australian forensic databases

Previous analyses of Australian samples have suggested that populations of the same broad racial group (Caucasian, Asian, Aboriginal) tend to be genetically similar across states. This suggests that a single national Australian database for each such group may be feasible, which would greatly facilitate casework. We have investigated samples drawn from each of these groups in different Australian states, and have quantified the genetic homogeneity across states within each racial group in terms of the "coancestry coefficient" F(ST). In accord with earlier results, we find that F(ST) values, as estimated from these data, are very small for Caucasians and Asians, usually <0.5%. We find that "declared" Aborigines (which includes many with partly Aboriginal genetic heritage) are also genetically similar across states, although they display some differentiation from a "pure" Aboriginal population (almost entirely of Aboriginal genetic heritage).     

一例牛胎儿的肾真性瘤

牛的先天性肿瘤报告不多。Misdorp最近复查了动物胎儿和初生动物(10天内)的先天性肿瘤和瘤样物(例如白血球增生)文献,而先天性肾真性瘤在以前(1965)没有报道过。在刊物中报道过二例牛胎儿,估计每例胎儿在第六个月流产。发现一例为多发性的肾外肿瘤,另一例为肾上单一的原发性肿瘤。牛的这两例和人的7月龄胎儿一例是文献中先天性肾真性瘤仅有报道的病例。     

塔吉克斯坦与中国的文化合作——起因、现状和前景

在塔吉克斯坦与中国建立外交关系的15年中,两个邻国的关系一直呈直线上升式发展.目前两国在政治、经济和人文领域的交往达到了历史最好水平.历史遗留的边界问题已经得到彻底和圆满的解决,开放和互信成为两国和两国人民之间交往的准则.