Genetic variation of 15 STR autosomal loci in the Maracaibo population from Venezuela

Allele frequencies for 15 short tandem repeats (STRs) autosomal loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, TH01, D13S317, D16S539, D2S1338, D19S433, vWA, TPOX, D18S51, D5S818 and FGA, included in the AmpFLSTR Identifiler, Applied Biosystems) were studied in the city of Maracaibo, Venezuela and were compared with other published Latin-American populations for the same loci. Population and forensic parameters were estimated.     

Population genetic study in two Transylvanian populations using forensically informative autosomal and Y-chromosomal STR markers

Our study provides population genetic data on two population samples collected in a Hungarian speaking region of Transylvania, Romania. Allele frequency and profile databases were generated on 17 autosomal STR loci (D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, VWA, FGA, TH01, TPOX, CSF1PO, Penta E and Penta D) as well as at the 12 European Y-STR extended haplotype loci (DYS19, DYS389-I/II, DYS390, DYS391, DYS392, DYS393, DYS385 loci, DYS437, DYS438 and DYS439). Data were compared to a Central Hungarian (Budapest region) population sample [B. Egyed, S. Füredi, M. Angyal, L. Boutrand, A. Vandenberghe, J. Woller, Z. Padar, Analysis of eight STR loci in two Hungarian populations, Forensic Sci. Int. 113 (2000) 25-27] that was used as a reference group of the Hungarian population. Calculating the F(ST) indices and with the pairwise comparisons of interpopulation molecular variance (AMOVA) the two populations from Transylvania could be fit into the Hungarian population data showing less substructuring effects as compared to the previous findings in Hungary [B. Egyed, S. Füredi, M. Angyal, L. Boutrand, A. Vandenberghe, J. Woller, Z. Padar, Analysis of eight STR loci in two Hungarian populations, Forensic Sci. Int. 113 (2000) 25-27; B. Egyed, S. Füredi, M. Angyal, I. Balogh, L. Kalmar, Z. Padar, Analysis of the population heterogeneity in Hungary using fifteen forensically informative STR markers, Forensic Sci. Int. 158 (2005) 244-249].     

创制猪水泡病疫苗的初步研究

本文报告了猪水泡病病毒的生产、灭能以及用它作成的疫苗对猪的免疫原性。病毒在IB-RS-2系细胞的单层和悬浮培养中都能培养。在两种系统中于大约24小时内都能获得每毫升10~(8.5)至10~(9.0)产斑单位的病毒滴度。目前可用单层细胞系统来大规模生产病毒。 用AEI在26℃和37℃使病毒灭能都表现是按照一级反应进行的。在大量样品的试验证实用这种药品灭能的病毒悬浮液是安全的。用BPL灭能时,即令是用高到0.25％的浓度,也未能生产不含感染性病毒的产品。 用氢氧化铝和皂角甙或者油作为佐剂并含组织培养液1.0毫升的抗原作成的疫苗能对强烈的攻击提供高度的保护力。注射氢氧化铝—皂角甙疫苗和油质疫苗的试验猪的病损评分分别为0.7和0.4分,与此相比,一个未免疫的对照组的病损评分则为14.3分。免疫后形成的免疫球蛋白遵循在其他小核糖核酸病毒所见的IgM和IgG图案。     

越南在东南亚的行径——这一地区日益不稳定的根源

尽管东盟各成员国经济上获得了显著进展,国内安定,并且逐步走向民主化,但它们却面临一个日益增长的共同威胁:即由于越南在印度支那的行径而造成地区性的不稳定。东盟各国特别是泰国、马来西亚和印度尼西亚终于理解到1975年以后的时期印度支那局势发展同它们自身安全和福利之间错综复杂的关系。自那时以来,它们一直勉为     

彭城大盗落网记

引子公元1994年6月2日,徐州铁路看守所一号监房里,一个身戴脚镣手铐的重刑人犯再次狂叫,看守小张即快跑过去,打开那监门小小的洞孔,这个年轻的人犯看见了看守,泪痕满面:“政府,你们早一点送我‘走’吧……。”他,就是横行彭城二年,先后盗窃48个党政机关和企事业单位,作案83起,累计盗窃人民币及实物折款近6万元,粮票2700余斤,号称“彭城大盗”的谢义铮。     

Intimate partner violence research in the health care setting: what are appropriate and feasible methodological standards?

The past 20 years of research has exposed the profound cost of intimate partner violence (IPV) in health care problems and health care dollars for victims and bystanders. As a result, professional organizations encourage clinicians to identify IPV victims and to refer them to community resources. To date there is little evidence to show the value of these efforts, and many completed studies are criticized for methodological weaknesses. IPV studies are challenging to design, and the double-blind randomized controlled trial may be an impossible standard. To move forward, funders and study committees are encouraged to reassess the standards for IPV research methodologies.     

Toxicologic aspects of deaths due to falls from height

A prospective study of 161 victims of falls from height is reported. The aim was to determine the interest of systematic qualitative and quantitative toxicological analysis in such fatalities. The primary cause of death was suicide (84.5%), followed by accidents (7%) and homicide (1%). In the remaining 7.5%, cause of death was undetermined. In the suicides, there was evidence of psychotropic medicines in 57% of the observations, with a much higher proportion of benzodiazepines and antidepressants in women than in men. Quantitative toxicologic analysis showed overdosing on medication in 16 suicide victims, with toxic levels in 11 of these. Systematic qualitative and quantitative toxicologic analysis made a significant contribution to the diagnosis of suicide by revealing either an unknown psychiatric treatment or a toxic level.     

Genetic polymorphisms of 15 STR loci in two Tibetan populations from Tibet Changdu and Naqu, China

The allelic distribution of 15 short tandem repeat (STR) loci included in the AmpFl STR Identifiler kit was examined in 100 Changdu Tibetan and 118 Naqu Tibetan unrelated individuals living in the Tibet Province, PR China. The distribution of these observed genotypes was not significantly different from the expected distribution according to Hardy-Weinberg equilibrium.