Sudden death due to congenital pericardial defect: an autopsy case

Pericardial defects are rare in childhood and outcome is usually benign. Patients may be asymptomatic, but chest pain, emboli, arrhythmia, and sudden death have been described in the literature. We report the case of a 12-year-old boy who suddenly died after mild exercise. A left-sided pericardial defect with a diameter of 8 cm was detected on medico-legal autopsy.     

Resolving Incompatibilities of Bilateral Investment Treaties of the EU Member States with the EC Treaty: Individual and Collective Options

Bilateral Investment Treaties (BITs) concluded by the EU Member States contain substantially similar clauses, including free movement of capital and investor‐to‐state dispute resolution. Article 307 EC provides for the primacy of pre‐accession treaties over the EC Treaty and simultaneously requires the Member States to eliminate their mutual incompatibilities. The European Court of Justice has declared that free movement of capital clauses of Austrian and Swedish pre‐accession extra‐EU BITs are incompatible with the EC Treaty as they will impede any restrictions on the movement of capital imposed as future Community legislation. A similar ‘free movement of capital’ clause is present in all extra‐EU BITs of the Member States, whether pre‐ or post‐accession. Article 307, however, does not apply to the post‐accession treaties which are equally capable of contriving the same consequences of impeding the application of the EC Treaty. In addition, the application of intra‐EU BITs provides investors from BIT party states access to the investor‐to‐state dispute resolution which is not available to investors from the Member States who do not have BITs with those Member States. This is discrimination and may distort the principle of equal treatment within the EU. Furthermore, the newly acceding EU States are facing extensive arbitral claims for carrying out the BIT‐EU conflicting obligations within their respective territories.     

Initiatives that Counter Violent Radicalization but are Perceived as Suitable by Targeted Communities

To redress the scourge of violent extremism, an array of policies, programs, and practices have been implemented. Yet, these initiatives could sometimes conflict with the preferences of individuals who may be susceptible to radicalization. To illustrate, some initiatives might challenge the values of these individuals. The degree to which these individuals feel significant or important might thus decrease—a decrease that has been shown to rouse the pursuit of violent radicalization. To prevent this complication, two studies were designed to uncover programs, policies, or practices that align to the preferences of people who may be more susceptible than average to violent radicalization. In Study 1, three individuals who had been charged with crimes related to terrorism, but had since relinquished extremism, were asked to suggest initiatives they feel could prevent violent radicalization in Australian Muslims. Similarly, in the second study, young Australian Muslim adults who rejected extremist ideologies were asked the same question. The participants advocated initiatives that foster tolerance towards diverse perspectives, inspire individuals to trust their values and intuition, encourage civic engagement, improve the credibility of imams, and enable people to derive strength from their community. A review of previous literature indicates that many of these initiatives might not only resonate with the preferences of individuals who may be vulnerable to violent extremism but could also foster a sense of significance and meaning in life—an experience that tends to prevent radicalization.     

Heroin profiling: mannitol hexaacetate as an unusual ingredient of some illicit drug seizures

Mannitol hexaacetate (MHA) has been detected by GC-MS in some brown illicit drug seizures in which diacetylmorphine (DAM) was completely lacking. The presence of MHA as a genuine ingredient of the drug seizures rather than a storage- or an analytical artifact, formed by transacetylation of mannitol with the DAM in the heroin, has been verified. It is argued that MHA was formed as a result of the addition of mannitol, as diluent, before the acetylating step in the process of the heroin preparation. This early dilution in the production and distribution chain of the illicit drug is deemed as peculiar, nonetheless it may be highly indicative of a specific production process of heroin in a trafficking organization.     

Deaths Related to Tractor Accidents in Eskişehir,Turkey: A 25‐Year Analysis

This study aimed to analyze deaths related to tractor accidents in Eski?ehir Province and characteristics of these cases to provide data and suggestions along with the literature. The cases involved individuals died due to tractor‐related accidents were retrospectively examined between 1992 and 2016 (25‐year period). Demographic data related to the cases and crime scenes, characteristics of events, and autopsy findings were evaluated. In the 25‐year period, 61 individuals (88.5% males, average age: 48.7 years) died due to tractor accidents in Eski?ehir Province, and approximately 45.9% of these accidents most commonly involved tractor rollover. Deaths due to tractor accidents will be decreased by raising awareness among tractor drivers, preventing young individuals from driving tractors, not allowing individuals to drive without license, making mechanical and physical features of tractors suitable for agricultural activity to be performed, ensuring their safety for travel and use, and avoiding carrying passengers on tractors.     

(In)-Equality in the Allocation of R&D Resources for Rare Diseases

This paper analyses the allocation of R&D investments within rare diseases and identifies the characteristics of rare diseases that appear to lead R&D resources. Rare diseases affect less than 1 in 2000 citizens. With over 7000 recognised rare diseases and 350 million people affected worldwide, rare diseases are not so rare when considered collectively. Rare diseases are generally underserved by drug development because pharmaceutical industries consider R&D investments in rare diseases too costly and risky in comparison with the low expected returns due to the small population involved. We use data on rare diseases research from Orphanet along with academic publications per rare disease from bibliographic databases. We test the existence of inequalities in R&D investments within rare diseases and identify the disease characteristics that appear to lead R&D investments using dominance tools and bilateral tests. We show that rare diseases in children and with a smaller prevalence, such as ultra-rare diseases, are underserved by R&D. R&D investments appear to be concentrated in more profitable research areas with potentially larger sample size and adult population.

     

What you sell is what you lend? Revealing complexity of <Emphasis Type="Italic">riba</Emphasis> in loan contract

The purpose of this paper is to resolve and examine the possible modus operandi of riba on selling and loan contract according to the Sharia’s precepts. This paper investigate the Qur’an, hadith, and juristic views on such relevant issues based on the survey done on the several sources, i.e., previous studies, Al-Qur’an and Al-Hadith and juristic views and deviate from the existing studies in two aspects, i.e., the selling and buying of goods do not involve riba and also the banks provide loan without riba. The findings of this paper are: First, the concept of interest in lending is widely accepted both in theory and practice. Second, riba exists in selling and lending. Third, the categorization and application of extensive and complex subjects of riba in economic life bring all speculative and usurious transactions under the rubric of riba prohibition. This paper important because express and disclosure riba in both exchange of goods and loans, also the social and economic developments. This is an original undertaking of this paper.     

Understanding urban Alevism through its socio-spatial manifestations: cemevis in İzmir

Cemevis emerged as the spaces of the Alevi identity in contemporary cities of Turkey. On the basis of in-depth interviews conducted in ?zmir with the heads of cemevi associations, this study claims that, while cemevis were enforced by the process of urbanization, they have been transforming the Alevi practices and collective organizations and eventually constructing a new type of Alevism as to religious practices, community institutions and collective imagination. Though no legal–political recognition has yet been granted to cemevis as the places of worship, they have established themselves as central institutions of urban Alevis with their extensive use beyond the limited oppositional categorization of culture–religion. This denial of legal status which has been seen as the violation of basic human rights is one of the main constitutive dynamics in the ongoing debates on Turkey's Alevi question. It is to such an extent that the denial of legal status to cemevis has today come to be identified by Alevi groupings with the denial of Alevi collective identity itself.