Staphylococcal scalded skin syndrome mimicking child abuse by burning

Child abuse by burning comprises 6–20% of all child abuse cases, but misdiagnosis may arise in cases of some medical conditions. We present two cases of suspected inflicted burns, later diagnosed as staphylococcal scalded skin syndrome (SSSS).     

Die Grünen and the Israeli-Palestinian Conflict

This paper discusses the German Greens' recent policy on Israel and Palestine, from the beginning of the first red-green federal government to the present. It looks at Green Foreign Minister Joschka Fischer's diplomatic role in the Middle East, and the Greens' current very "mild" policy with regards to Israel, especially when compared to earlier Green attitudes to the region. This is explained with reference to both the continuing relevance of German history to German foreign policy, and the constraints that participation in the federal coalition — and supplying Germany's Foreign Minister — place on the Greens. The influence of history and power on the German Greens is further illustrated by a comparison of German Green attitudes to Israel with the US Greens' much more critical position.     

An evaluation of the quality of impact assessment in the European Union with lessons for the US and the EU

Governments throughout the world are requiring greater use of economic analysis as a way of informing policy decisions. This paper provides a comprehensive analysis of the use of impact assessment in the European Union, using US assessments as a benchmark. We find that recent EU impact assessments include more economic information than they did in the past, although important items are still missing. We also provide evidence that the quality of EU impact assessment increases with the expected cost of a proposal. Furthermore, we find that the quality of EU assessments that report high total costs is similar to that of US assessments.     

Vedāntic Analogies Expressing Oneness and Multiplicity and their Bearing on the History of the Śaiva Corpus. Part I: Pariṇāmavāda

Journal of Indian Philosophy - This article, divided into two parts, traces and discusses two pairs of analogies invoked in Sanskrit(ic) literature to articulate the paradox of God’s oneness...     

Vedāntic Analogies Expressing Oneness and Multiplicity and Their Bearing on the History of the Śaiva Corpus. Part II: Vivartavāda

Journal of Indian Philosophy - This article, divided into two parts, traces and discusses two pairs of analogies invoked in Sanskrit(ic) literature to articulate the paradox of God’s oneness...     

Is Canadian intellectual property leaving Canada? A study of nanotechnology patenting

In this study we explore the patent ownership for the innovations created by Canadian nanotechnology inventors. We find that although there is a great innovative potential and inventive productivity among Canadian researchers, a lot of the intellectual property actually leaves the country: Around 50% of the nanotechnology patents invented by Canadian inventors are owned by foreign assignees. We also note the predominance of private companies among the patent owners. Almost one-third of all the Canadian-invented nanotechnology patents is assigned to a single American firm, Xerox Corporation. Furthermore, we explore the role of Canadian nanotechnology star inventors. The results show that the fruits of their great inventive productivity are collected outside Canada.     

A case of fatal overdose involving both hydromorphone and kratom

Kratom is a plant originating in Southeast Asia that has been used for its dose-dependent stimulant and opioid effects. The main active compound in kratom is mitragynine, an alkaloid with affinity for the mu-opioid receptor. Toxicity and fatalities related to kratom use have increased substantially in recent years. In this case report, we describe a 44-year-old man who was found deceased in bed. The only significant finding at autopsy was abdominal distension with >4 L of ascites. Toxicology testing was performed on femoral blood which showed 79 ng/mL of hydromorphone, 560 ng/mL of mitragynine, and 240 ng/mL of olanzapine. In addition, creatinine and urea in vitreous humor were significantly elevated, consistent with renal impairment. Death was attributed to hydromorphone toxicity with mitragynine being a contributing factor.     

Phenibut screening and quantification with liquid chromatography–tandem mass spectrometry and its application to driving cases

An analytical strategy for identification by an LC–MS/MS multitarget screening method and a suitable LC–MS/MS based quantification were developed for the psychotropic drug phenibut. The samples analyzed were collected during traffic control and were associated with driving under the influence of drugs. A positive sample for phenibut was identified in a single case of driving under the influence. The quantification revealed a drug concentration of 1.9 μg/mL. An interaction with blood alcohol (BAC = 0.10%) was discussed as the explanation of the way of driving and deficit manifestations observed (swaying, nystagmus, quivering of the eyelid, and reddened eyes). According to the available information, the quantified phenibut concentration could be explained by an intake of four tablets (self-reported) during the day containing 250 mg of the drug. Chromatography was performed with a Luna 5 μm C18 (2) 100 A, 150 mm × 2 mm analytical column, and a buffer system consisted of 10 mM ammonium acetate and 0.1% acetic acid (v/v) included in mobile phases marked as A (H₂O/methanol = 95/5, v/v) and B (H₂O/methanol = 3/97, v/v). An effective limit of detection (LOD = 0.002 μg/mL) could be achieved for the multitarget screening method. The quantification of phenibut was performed on a second LC–MS/MS system with LOD/LOQ values of 0.22/0.40 μg/mL. Since phenibut quantification data are rare, the presented information can be used with caution for evaluation of positive cases in the future.     

Fat embolism syndrome associated with atraumatic compartment syndrome of the bilateral upper extremities: An unreported etiology

Fat embolism syndrome (FES) is a potentially life-threatening condition that develops when fat embolism leads to clinical symptoms and multisystem dysfunction. The classic triad of respiratory distress, neurologic symptoms, and petechial rash are non-specific, and the lack of specific laboratory tests makes the diagnosis of FES difficult. Although FES is most common after long bone fractures, multiple conditions some of which are atraumatic have been associated with the development of FES. We report a case of FES that occurred in the setting of a non-traumatic compartment syndrome of the upper extremities. The pathologic and clinical findings, pathophysiology, diagnostic challenges, and pathologic methods to properly diagnose FES are discussed with a review of the relevant literature. This case highlights the importance of the autopsy in making a diagnosis of FES in cases where death could otherwise be incorrectly attributed to multi-organ system failure, shock, or sepsis.