Death Caused by Toxic Epidermal Necrolysis (Lyell Syndrome)

Abstract: Toxic epidermal necrolysis (TEN) is characterized by fever, scalded appearance of the skin, and epidermolysis associated to blister formation and exfoliation, and it is caused by hypersensitivity reaction to a drug. The authors report two cases of death as a result of TEN; both referred to old aged women treated with a polytherapy including allopurinol. Both patients displayed erythematous skin lesions similar to scald burns and epidermolysis at the face, chest, and abdomen and died shortly after hospitalization. Autopsy findings and histological examinations revealed epidermal necrolysis and confirmed the clinical diagnosis. A strict time‐correlation between allopurinol administration and symptoms was evidenced. Because of its iatrogenic origin, TEN often arises suspicions of medical liability; however, because of its unpredictable nature, the occurrence of this syndrome cannot be ascribed to the medical staff whose main task is the rapid diagnosis and the correct management.     

A best practice model for e-consumer protection

This article outlines a set of criteria for assessing the value of e-consumer protection schemes. It is intended that it be used as a tool, for policy-makers, industry associations, corporations and consumer organisations in all jurisdictions, seeking to assess the appropriateness of their consumer protection regulation. It can be used to devise new, or improve existing, policies, and it can also be used to compare the usefulness of e-consumer protection in different jurisdictions. It commences with a brief review of existing frameworks for the protection of e-consumers, which demonstrates the need for a model that uncompromisingly presents the needs of consumers. An overview of the model is provided, followed by a presentation of the model's key features. A further section identifies the several ways in which the model can be applied in order to improve the usefulness of e-consumer protection. An earlier version of the model was published in checklist form (Clarke R. ‘A Major Impediment to B2C Success is … the Concept 'B2C' Invited Keynote, Proc. ICEC'06, Fredericton NB, Canada, 14–16 August 2006, at http://www.rogerclarke.com/EC/ICEC06.html#TNT). The present article revises and expands that checklist, and presents the rationale underlying each item in it.     

WHY A LAWYER?—THE IMPORTANCE OF CLIENT‐DIRECTED LEGAL REPRESENTATION FOR YOUTH

This article begins with a discussion about the importance of ensuring that all children have lawyers in abuse and neglect cases. Lawyers provide a vital role in giving youth a voice in proceedings that sound profoundly affect their lives. The article then discusses why the client‐directed lawyer's role is consistent with federal law and legal ethics. Finally, the article discusses the growing support for client‐directed representation and what the American Bar Association has done to support this type of child representation.     

World War One Italian and Austrian soldier identification project: DNA results of the first case

We report the results of an attempt to identify the supposed remains of a famous World War I (WWI) Italian soldier who was killed in battle along the Italian front in 1915.Thanks to the availability of offspring from both paternal and maternal lineage Y-STRs and mtDNA were analysed and both showed a clear exclusion scenario: the remains did not belong to the supposed war hero.This is the first effort of identification of the remains of soldiers who perished during World War I within a multidisciplinary project aimed at the retrieval of historical and cultural aspects linked to WWI, and the systematic study of the remains of soldiers and ultimately their identification. This last step involves both Italian and Austrian laboratories.     

Mainstreamed voluntary sustainability standards and their effectiveness: Evidence from the Honduran coffee sector

Voluntary Sustainability Standards have become a popular private governance framework for more sustainable agri-food value chains. Yet, amid increasing concerns over the decoupling of standards and practices, it is still unclear to what extent agricultural standard requirements are implemented on the ground, and what may account for such differential implementation. This study employs a novel dataset of 659 Honduran coffee producers to examine this puzzle, focusing on the most widely used standards in the coffee sector (Common Code for the Coffee Community, Fairtrade, Fairtrade/organic, UTZ Certified, and Rainforest Alliance). It first presents results on implementation and behavioral change, based on matched groups of certified and non-certified farmers, for eight representative social and environmental sustainability practices. Analyzing determinants of implementation success, it finds that the stringency of rules – if they are known by farmers – and the level of farm-gate prices are significantly correlated with farmers’ performance and lower levels of decoupling across a majority of indicators. These results speak to the importance of supporting small-scale actors’ awareness of and financial capacity to comply with proposed sustainability rules.     

The Trajectories of Crime at Places: Understanding the Patterns of Disaggregated Crime Types

Objectives

Investigate the spatial concentrations and the stability of trajectories for disaggregated crime types on street segments and intersections in Vancouver, Canada.

Methods

A longitudinal analysis of 16 years of crime data using street segments and intersections as the units of analysis. We use the k-means non-parametric cluster analysis technique considering eight crime types: assault, burglary, robbery, theft, theft of vehicle, theft from vehicle, other, and total crime.

Results

The overall results for the individual crime types versus overall crime are similar: crime is highly concentrated regardless of crime type, most street segment and intersection trajectories are stable over time with the others decreasing, and most decreasing trajectories are in the same general areas. However, there are notable differences across crime types that need to be considered when attempting to understand spatial pattern changes and implement crime prevention initiatives.

Conclusions

The law of crime concentration at places holds in Vancouver, Canada for disaggregated crime types in the context of spatial concentrations and their stability over time. However, notable differences exist across crime types that should be accounted for when developing theory or policy.

     

An Isolated Perfused Rat Kidney Model for the Evaluation of the Effect of Glucose on Renal Tubular Epithelial Morphology

An isolated perfused kidney model was used to evaluate the effect of hyperglycemia on renal tubular epithelial cell morphology. Ten Sprague–Dawley rat kidneys were perfused with Krebs–Henseleit buffer containing 70 mmol/L of glucose (five for 1 h and five for 2 h). Two control groups consisted of 10 kidneys perfused with Krebs–Henseleit buffer without hyperglycemia (five for 1 h and five for 2 h), and 10 nonperfused contralateral kidneys placed in the same environment for the same duration. The hyperglycemia group had significantly increased renal tubular vacuolization (p < 0.001) compared to both control groups at 1 and 2 h. The isolated perfused kidney model recapitulates the renal tubular vacuolization phenotype found in hyperglycemia and may be a potential tool for the investigation into causal factors in renal histology. The full pattern of the Armanni–Ebstein phenomenon was not, however, reproduced, suggesting that this change requires more time or involves more complex factors.     

Blurring or Shifting of Policy Frames?: Institutionalization of the Economic-Environmental Policy Linkage in the European Community

This article investigates how "policy frames" have shaped the way European Community actors perceive the policy linkage between market integration and environmental policy. The article contends that there are three Community policy frames: conditional, classic, and sustainability. They form alternative "packages" of policy ideas defining the relationship between economic and environmental policy. The article provides an analysis of how actors embed these frames in the Community's institutional framework.To illustrate the general impact of policy frames on the environmental arena, the article explores two cases: waste management policy, and the integration of environmental concerns into the Community's agricultural policy. The article concludes by highlighting the different factors that promote and undermine the formation of "thick" institutional structures likely to integrate environmental and economic policy objectives.     

Women,ordination and the church

Margaret Ann Franklin (ed), The Force of the Feminine (Allen & Unwin) Sydney, 1986; Margaret Ann Franklin and Ruth Sturmey Jones (eds), Opening the Cage (Allen & Unwin) Sydney, 1987; Kate Nelson and Dominica Nelson (eds), Sweet Mothers, Sweet Maids (Penguin) Ringwood, 1986; Karen Armstrong, The Gospel According to Woman (Elm Tree) London, 1986; Kerreen Reiger, The Daughters of Eve and Mary: Women in the Modern World, Occasional Paper No. 6, IPOFAC, Mission of St James & St John, Melbourne, 1987.     

Exploring the psychological and somatic impact of identity theft

Identity theft is a new and growing form of white-collar crime. This exploratory study examined the psychological and somatic impact of identity theft and coping methods utilized by victims. Thirty-seven victims of identity theft participated in regional victim focus groups. Participants completed a victim impact questionnaire designed by the authors and the Brief Symptom Inventory-18 (BSI-18). The majority of participants expressed an increase in maladaptive psychological and somatic symptoms post victimization. Results on the BSI indicated that identity theft victims with unresolved cases, in contrast to those with resolved cases, were more likely to have clinically elevated scores when compared with a normative sample. Relatively similar coping mechanisms were utilized across victims. The results from this study suggest that victims of identity theft do have increased psychological and physical distress, and for those whose cases remain unresolved, distress is maintained over time.