Engines need transmission belts: the importance of people in technology transfer offices

The Journal of Technology Transfer - Over the last 20 years, universities and Public Research Organizations have increased their efforts to transfer their research results towards...     

Are regulatory agencies independent in practice? Evidence from board members in Spain

Are the board members of regulatory agencies (regulators), taken as a particular cluster within the public sphere, independent of elected politicians and tenured bureaucrats? How can we assess their independence in practice, beyond formal rules? To address these questions, this paper delves into two key dimensions: board members' social connections and their security of tenure in office. Firstly, we focus on regulators' identity as policy adjudicators and examine their political and administrative relations. In doing so, we expect to understand better how regulators' social and political situations may influence their behavior. Secondly, we assess their political vulnerability through political cycles in order to measure their de facto independence over time. Additionally, variations in these two dimensions are compared with respect to the effect of different de jure appointment rules. We contrast these expectations with the empirical evaluation of board members of regulatory agencies in Spain (1979–2010). Thus, we confirm that regulators who have an administrative profile are more vulnerable to political changes than those with political ties, while appointment rules have an influence on their political vulnerability.     

Doxepin and nordoxepin concentrations in body fluids and tissues in doxepin associated deaths

Body fluids and tissues in eight doxepin (Dox)-related deaths were investigated in order to prove whether the individual concentration of Dox, the concentration sum of parent drug and its active metabolite N-desmethyldoxepin (NDox) or the concentration ratio Dox/Ndox valuably contribute to making a cause of death determination. Individual case histories were shortly described. Dox and NDox concentrations were determined by LC–MS/MS. Dox concentration measured from two cases was well within a concentration range considered therapeutic, whereas subtherapeutic dosing may have occurred in another two cases. There were two cases of fatal Dox ingestion, as well as a case of high dosage and advanced putrefaction, respectively. The liver concentration sum may be more useful if a fatal ingestion cannot be clearly separated from a person's medication usage. High concentrations could be observed in lung tissue, and combined concentrations of Dox and NDox may also be helpful in making a cause of death determination. There was a trend to a higher concentration sum in the brain with increasing combined levels in blood. Overall, the sum of the absolute figures allows a more accurate interpretation in Dox-related deaths as compared to the molar concentration ratio which may be helpful in acute ingestion. Determination of the N-desmethyl metabolite along with its parent is recommended and analysis should include more than a single specimen.     

The Correlation Between Skeletal Weathering and DNA Quality and Quantity*

Abstract: Mitochondrial DNA analysis of skeletal material is invaluable in forensic identification, although results can vary widely among remains. Previous studies have included bones of different ages, burial conditions, and even species. In the research presented, a collection of human remains that lacked major confounders such as burial age, interment style, and gross environmental conditions, while displaying a very broad range of skeletal degradation, were examined for both mitochondrial DNA (mtDNA) quality and quantity. Overall skeletal weathering, individual bone weathering, and bone variety were considered. Neither skeletal nor bone weathering influenced DNA quality or quantity, indicating that factors that degrade bone do not have the same effect on DNA. In contrast, bone variety, regardless of weathering level, was a significant element in DNA amplification success. Taken together, the results indicate that neither skeletal nor individual bone appearance are reliable indicators of subsequent mtDNA typing outcomes, while the type of bone assayed is.     

Rupture of ascending aorta secondary to esophageal perforation by fish bone

Perforations of both esophagus and aorta after swallowing foreign bodies have been described, with aorto-esophageal fistulas at the level of the descending aorta or aortic arch. We present the case of a 48-year-old man with esophageal perforation by fish bone, mediastinitis, and evidence of perforation of the ascending aorta during surgical drainage of the mediastinum. At autopsy, a fish bone was found under the aortic arch. Serial histological macrosections of the mediastinic block allowed reconstruction of the type of injury suffered and a thorough analysis of mediastinic structures, with preservation of topographic relationships. Direct demonstration of the perforation of the posterior wall of ascending aorta was provided. Histological examination ascribed aortic perforation to migration of the fish bone and direct injury. This is the first anatomical and pathological study of an autopsy case of perforation of the ascending aorta by fish bone.     

Predicting Institutional Violence among Death Row Inmates: The Utility of the Sorensen and Pilgrim Model

The (Sorensen and Pilgrim, An actuarial risk assessment of violence posed by capital murder defendants. J Crim Law Criminol 90:1251–1270, 2000) actuarial model was developed to predict institutional violence among life-sentenced murderers. However, despite its presentation at capital sentencing, the model has not been validated on death row inmates specifically. This study examined the association between Sorensen and Pilgrim model scores and five types of institutional violence (serious assaults, minor assaults, verbal assault/threats, prison order offenses, and non-violent infractions) among a sample of 155 individuals who had been incarcerated on death row in Texas. Results revealed that risk scores performed better for non-violent infractions than for serious assaults, calling into question the utility of this measure for capital sentencing evaluations.

Fatalities associated with the termination of electrical services

The worldwide dependence on electricity to support the needs of today's society is often taken for granted and, as such, the hazards associated with the termination of electrical services are often neglected. Whether electrical services are unintentionally terminated as the result of severe weather or intentionally terminated as the result of nonpayment of utility bills, the ensuing conditions may lead to injury or death in affected individuals. We performed a retrospective review of all deaths investigated by the Onondaga County Medical Examiner's Office between 1999 and 2004. Our case database was searched for causes of death that included hypothermia, hyperthermia, carbon monoxide, fire, electrocution, and/or electricity. Further review of these cases was undertaken to determine the potential relationship between the death and the termination of electrical services. Seven fatalities were found to be associated with the termination of electrical services. Four fatalities resulted from its unintentional termination and 3 were a consequence of intentional termination. In reporting these deaths, we hope to emphasize the potential dangers associated with the termination of electrical services and explore the informational programs and public health laws that are in place to limit the associated potential negative outcomes.     

Extensive Petechiae in Attempted Self-Strangulation

Abstract:  A 29-year-old Korean man reported to have been robbed, bound, and gagged by a stranger in his apartment. Clinical findings included extensive petechiae to his face and tramline patterned abrasions and ligature furrows to his neck and face as well as his wrists. Initially, no other leads in the investigation existed and a robbery was assumed to have taken place. The man eventually confessed to fabricating the story and to having self-induced the ligature marks by subluxating his jaw at the temporomandibular joint and hooking the rope closest to the back of his neck on the corner of table. The man demonstrated this unsuspected ability to law enforcement officers. As a motive for his unconventional behavior, he confessed to engaging in autoaggressive behavior as punishment for "losing face" after his ex-girlfriend terminated her pregnancy. This case demonstrates that petechiae due to neck compression also may occur in the living and are due to vascular compression and not lethal hypoxia.     

Modern Interpretations of Sustainable Development

Early interpretations of sustainable development based on weak sustainability address neither the limits to the earth's resilience nor our failure to curb consumption. Given the challenges facing the earth today, especially climate change, a much more meaningful instrument is required and a new ethic based on the ecological carrying capacity of the Earth. The article examines the impact of those early interpretations before exploring the importance of ecological sustainability as the moral and (potentially fundamental) legal principle underpinning the concept of sustainable development. It examines the influence of the climate change agenda before examining the mechanisms available to make this ethic operational. Sustainable development has the capacity to set meaningful objectives, duties and rules, and provide boundaries for decision making, as reflected in recent legislation. Enhancing ecological sustainability through improving supply and impact is relatively easy for governments, businesses, and individuals; reducing consumption is much harder, and will require strong leadership.