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91.
Perlin MW Legler MM Spencer CE Smith JL Allan WP Belrose JL Duceman BW 《Journal of forensic sciences》2011,56(6):1430-1447
Abstract: DNA mixtures with two or more contributors are a prevalent form of biological evidence. Mixture interpretation is complicated by the possibility of different genotype combinations that can explain the short tandem repeat (STR) data. Current human review simplifies this interpretation by applying thresholds to qualitatively treat STR data peaks as all‐or‐none events and assigning allele pairs equal likelihood. Computer review, however, can work instead with all the quantitative data to preserve more identification information. The present study examined the extent to which quantitative computer interpretation could elicit more identification information than human review from the same adjudicated two‐person mixture data. The base 10 logarithm of a DNA match statistic is a standard information measure that permits such a comparison. On eight mixtures having two unknown contributors, we found that quantitative computer interpretation gave an average information increase of 6.24 log units (min = 2.32, max = 10.49) over qualitative human review. On eight other mixtures with a known victim reference and one unknown contributor, quantitative interpretation averaged a 4.67 log factor increase (min = 1.00, max = 11.31) over qualitative review. This study provides a general treatment of DNA interpretation methods (including mixtures) that encompasses both quantitative and qualitative review. Validation methods are introduced that can assess the efficacy and reproducibility of any DNA interpretation method. An in‐depth case example highlights 10 reasons (at 10 different loci) why quantitative probability modeling preserves more identification information than qualitative threshold methods. The results validate TrueAllele® DNA mixture interpretation and establish a significant information improvement over human review. 相似文献
92.
Lyons B 《Medical law review》2011,19(1):55-85
Children may sometimes undergo healthcare procedures that are not intended to improve their health status. Such interventions might include the use of young children as bone marrow donors or their enrolment in non-therapeutic research. One of the justifications used to legitimise these interventions is the premise that children have obligations to others; to their family in the case of related bone marrow transplantation, and to wider society in the case of non-therapeutic research. However, this 'obligation model' (the notion that children possess positive obligations to advance the health status of others) fails as a justificatory paradigm because it is based upon a confusion, identified by Hart, between two notions; that of 'being under an obligation to do something' and that of 'being obliged to do something'. Instead the 'obligation model' is a device employed to put a justificatory gloss upon a consequentialist decision-making process; removing the legitimising gloss allows for a more transparent look at the conflict between parental rights and an individual child's right to bodily integrity. 相似文献
93.
94.
Barry J. Koch 《Journal of Police and Criminal Psychology》2010,25(2):90-98
When a suicide is completed, police officers are often among the first responders. Little attention has been paid to the emotional
and psychological impact on the police officer in this specific situation. This study examines the effects encounters with
completed suicides have on the emotional and psychological well-being of the police officer. This is a qualitative study,
which intends to bring alive the feelings, thoughts, actions, choices, and challenges of police officers who have encountered
completed suicides as imparted through participants' stories. Interviews were done with eight police officers. In addition,
interviews were done with a coroner, a police chaplain, and a police psychologist to add some unique perspectives to the police
officers’ experiences of encountering completed suicides. Interviews were done in a semi-structured, focused format involving
an ongoing fine-tuning of questions. The overarching finding reveals the central role played by police culture in shaping
how police officers come to perceive this experience, and how they subsequently choose to mediate it. This study identifies
ten strategies police officers use to mediate this experience, and discusses the possible psychological consequences of employing
each strategy. 相似文献
95.
96.
ABSTRACTChildren under 10 are increasingly being referred to services for concerning problematic or harmful sexual behaviour, but information about interventions to support these children and their families is limited. A 3-year pilot of a group cognitive–behavioural intervention for children and their parents/carers is described. Forty-nine children were referred to the programme with 27 completing the programme in this period. This is the first intervention of its kind to be delivered with a UK population and demographic information is provided about the children who have been assessed, including information about age, gender, family composition and abuse history. Outcome data from the Trauma Symptom Checklist for Children, Child Sexual Behaviour Inventory, Strengths and Difficulties Questionnaire and the Parental Stress and Social Support Scale is reported. The available outcome data indicates the group has been largely beneficial in reducing problematic sexual behaviour. Key learning and implications for practice are discussed. 相似文献
97.
Barry K. Winetrobe 《The Journal of Legislative Studies》2013,19(1):1-13
Parliaments are difficult institutions to market and promote to their publics, partly because of their political nature and their institutional complexity. However, because good promotion requires a good ‘product’, thinking about parliaments in terms of their promotion can also focus attention helpfully on how they are actually structured and operated, thereby contributing to the improvement in their effectiveness, both internally and in relation to the wider polity. The Westminster and Scottish Parliaments can be usefully and conveniently compared and contrasted, both in terms of their parliamentary product, and in its promotion. such a comparative analysis highlights some of the defining characteristics of an effective parliament, such as an underlying vision and purpose, substantive institutional autonomy (especially in relation to the executive), and genuine public engagement. It also emphasises that both the operation and the promotion of a parliament are multi-layered tasks for parliamentarians and parliamentary staff. 相似文献
98.
99.
Barry Buzan 《The Pacific Review》2013,26(2):143-173
I argue that there is a distinct and longstanding regional structure in East Asia that is of at least equal importance to the global level in shaping the region's security dynamics. Without considering this regional level neither ‘unipolar’ nor ‘multipolar’ designations can explain East Asian international security. To make this case, I deploy regional security complex theory both to characterize and explain developments in East Asia since the end of the Cold War. The shift from bipolarity to unipolarity is well understood in thinking about how the ending of the Cold War impacted on East Asia. Less written about in Western security literature are the parallel developments at the regional level. Prominent among these are the relative empowerment of China in relation to its neighbours, and the effect of this, as well as of the growth of regional institutions, and the attachment of security significance to East Asian economic developments, in merging the security dynamics of Northeast and Southeast Asia. How China relates to its East Asian region, and how the US and China relate to each other, are deeply intertwined issues which centrally affect not only the future of East Asian, but also global, security. With the notable exception of some crisis between China and Taiwan, this whole pattern looks mainly dependent on internal developments within China and the US. Also significant is whether the basic dynamic of interstate relations in East Asia is more defined by the Westphalian principle of balancing, or by the bandwagoning imperative more characteristic of suzerain-vassal relationships. The main probability is for more of the same, with East Asian security staying within a fairly narrow band between mild conflict formation and a rather odd and weak sort of security regime in which an outside power, the US, plays the key role. 相似文献
100.
ABSTRACTTo answer the question of who wants to work for the government, scholars have relied on a few approaches, including sector preference, sector-based comparison of work motives, and sector-switching patterns of job mobility. The present study offers a related but distinct approach: perceived sector mismatch. The attractiveness of public sector jobs differs greatly across countries; thus, in order to present a more comprehensive study, we examine data from the U.S., New Zealand, and Taiwan, where attitudes towards public sector jobs differ significantly as a result of different public service laws and traditions. Across all three samples, we find that, among private sector employees, the preference for a public service job is related to socio-economic disadvantage. Among public sector workers, reasons for perceived sector mismatch vary, but often suggesting job dissatisfaction in current public sector jobs, rather than perceived advantages of the private sector (including compensation). These findings are followed by theoretical and practical implications from this comparative study. 相似文献