Oocyte donation for reproduction and research cloning--the perils of commodification and the need for European and international regulation.

The demand for women's egg cells is increasing and is leading to reproductive tourism and transnational oocyte trafficking. The article considers the regulatory landscape of oocyte donation in Europe and analyses different types, particularly whether oocytes are provided within or outside of the IVF context, and whether anonymity of the donor is legally possible or not. The bifurcation between different purposes of egg extraction, particularly the challenges raised by ova demands for cloning research (SCNT) are highlighted. In emphasizing the need for supranational regulation, nine rules for supranational minimum standards are proposed to protect both donor interests and the public good. A particular focus is directed to the commodification of oocytes with regard to the European principle of non-commercial, voluntary and altruistic donation.     

A special case of bolus fatality

The case of a 58-year-old man is reported, who had been hospitalized for almost 30 years for paranoid-hallucinatory schizophrenia. He was found unconscious in the clinic with a scarcely perceptible pulse and irregular breathing. Attempts at resuscitation were not successful. Looking at the corpse, no findings of particular value were noted. At the court-ordered autopsy, a mouse was found in the oral cavity; the head of the mouse was stuck in the laryngeal inlet. The cause of death was ascribed to asphyxia by alimentary bolus; the cause of death was apparently the effect of choking combined with a reflex action. In the large colon (megacolon) many metal objects were found. On the basis of the evidence, it was assumed that the mouse was already dead when the patient choked on it. A disturbance in the ability to swallow as a result of alcohol or medication was ruled out, as were neurological diseases.     

Suffocation death by occlusion of the airways with sand

Eleven cases are reported in which death occurred because of suffocation as a result of occlusion of the respiratory tract by sand (without thoracic compression: 3 cases) or being buried alive (8 cases). Two tables demonstrate the findings and circumstances in the events. Three cases are described in detail. A 22-year-old woman was manhandled by blows and kicks to the head and neck. She became unconscious and her head and neck were covered by a layer of sand so that she suffocated. A 42-year-old man was smothered, while unconscious, in a prone position with his face in the sand, after hard blows to the head by two culprits. A 17-year-old girl finally died by chocking. Previously the culprit had pressed her face into the ground, so that she aspirated particles of soil. The question of vital reactions during aspiration of sand was investigated by microscopic examination of the content of the air passage and by destroying parts of the lungs by sulphuric acid. Minimal aspiration of sand occurred in all cases. Although the postmortal remains were left in the ground, there was no postmortem penetration of sand into the air passage. Histological examinations were carried out to support the diagnosis of violent suffocation. In some cases, there were remarkable findings (mobilization of alveolar cells, hepatocelullar hydropic degeneration), but there were no typical or unanimous findings that pertained to all cases.     

Proportional Representation and the Framers

Techniques for conducting elections developed since 1800 have raised a question about the soundness of the American framers’ majoritarianism. John Stuart Mill notably argued that the framers’ desire to reward merit, as opposed to party loyalty, would be better served by a system of proportional representation that gave deserving minorities a voice. This article considers the likelihood that a system such as Mill proposed would have the results he hoped for; it concludes that such a system is more likely to worsen problems with the existing system of representation than to solve them.     

Information Exchange in Policy Networks

Information exchange in policy networks is usually attributed to preference similarity, influence reputation, social trust, and institutional actor roles. We suggest that political opportunity structures and transaction costs play another crucial role and estimate a rich statistical network model on tie formation in the German toxic chemicals policy domain. The results indicate that the effect of preference similarity is absorbed by institutional, relational, and social opportunity structures. Political actors choose contacts who minimize transaction costs while maximizing outreach and information. We also find that different types of information exchange operate in complementary, but not necessarily congruent, ways.