Validation and uses of a Y-chromosome STR 10-plex for forensic and paternity laboratories

Y-chromosome short tandem repeats (Y-STRs) provide valuable information in cases of rape and questioned paternity, and they allow for the genetic identification of male lineages. The present study validated a Y-STR 10-plex on the ABI PRISM 3100 Genetic Analyzer for use in forensic and paternity laboratories at Orchid Cellmark. Following optimization of the polymerase chain reaction, father-son pairs were analyzed to ensure that each pair generated identical haplotypes. This study demonstrated that the 10-plex is sensitive to 0.125 ng of input DNA and that female samples mixed with male samples did not interfere with Y-STR haplotyping. In a sample of 525 males, there were three instances of locus multiplication, two at DYS19 and one at DYS435. Overall, haplotype diversity was 0.996, suggesting that the 10-plex can effectively distinguish among male lineages.     

Standardized assessment of substance-related, other psychiatric, and comorbid disorders among probationers

This study examined the prevalence of alcohol- and substance-related disorders in a random sample of 627 adult probationers in Illinois. The investigation also explored the prevalence of major psychiatric disorders and their co-occurrences with alcohol and substance use disorders. To detect the presence of psychiatric disorders, researchers employed standardized assessment tools based on Diagnostic and Statistical Manual of Mental Disorders criteria. Overall, results showed that probationers had significantly higher rates of psychiatric disorders, substance use disorders, and co-occurring disorders compared with persons in the general population. In light of these findings, probation administrators are urged to invest more resources in treating drug use, mental illness, and codisorders, the latter of which is associated with a higher risk of violent behaviors.     

From analyst to negotiator: The OMB's new role

Dramatic changes in the executive and legislative budget processes over the last ten years have elevated the Office of Management and Budget (OMB) to a new position of power and importance. Within the executive branch the budget process has become more highly centralized in the president's office; and within the Congress a similar centralization has occurred. In both branches the OMB has become the key institution for coordinating the actions of the budget-making powers. At the same time, the much-discussed “iron triangles” explored by analysts of the budgetary system have lost much of their power to control the process. Although the OMB's active involvement in the congressional budget process diminished in 1983, the institutional relationships necessary for a more centralized budget process remain and can be reactivated to deal with the predicted enormous deficits.     

Organization and environment: The case of correctional personnel training programs

An intensive field study of 17 correctional personnel training programs was conducted to assess the organization-environment context in which these programs emerged and operated. Content analysis of site visit data revealed that correctional training programs less often served specific organization goal achievement purposes, and more often served as general strategies for coping with external environmental demands and pressures. A theoretical framework for examining organization-environment relations is described, and then used to analyze correctional training programs as a boundary-spanning activity that relates correctional organizations to environmental conditions. Organizational responses to environmental demands are placed along a continuum of adjustment ranging from survival, to adaptation, and innovation. Organizational responses to environmental demands, in turn, are related to training patterns that dovetail with the major needs of organizations and their personnel in efforts to adjust to the environment.     

Correlates of adolescent pessimism: A study of the beck hopelessness scale

This study examines correlates of the Beck Hopelessness Scale within an adolescent population. Consistent with studies employing adults as subjects, Hopelessness scores were found to be associated with depression and external locus of control. Additionally, a significant positive correlation was found between Hopelessness scores and an index of general maladjustment. The Hopelessness measure was, however, found to be unrelated to self-reported health status.Data for this study were collected as part of a larger investigation involved with the development and validation of an adolescent measure of life stress which was funded by a grant to the senior author from the University of Washington Graduate School Research Fund.Received Ph.D. in clinical psychology from Northern Illinois University. Major interests are clinical-child psychology and psychopathology of children and adolescents.Major interests are clinical-child psychology and suicide.