Investigation of trace inorganic elements in street doses of heroin

Sixteen trace elements found in 309 street heroin samples, piped water and contaminated water were determined using inductively coupled plasma-mass spectrometry. All the street heroin samples were found to contain high levels of sodium, a reflection of the use of sodium bicarbonate during heroin synthesis. Additionally, this element was also found to be one of the potential contaminants acquired from the piped water. Calcium could be derived from lime while iron, aluminum and zinc could have come from the metallic container used in the processing/cutting stage. The levels of these elements remained low in the heroin and it could be due to the dilution effects from the addition of adulterants. Statistical validation was performed with six links of related heroin samples using principal component analysis to find the best pretreatment for sample classification. It was obtained that normalization followed by fourth root showed promising results with 8% errors in the sample clustering. The technique was then applied to the case samples. Finally, the result suggested that the case samples could have originated from at least two major groups respectively showing unique elemental profiles at the street level.     

Older women, health, and social care in Singapore

A key demographic feature in the high-income country of Singapore is that women have longer years of life than men, and the aging pattern in Singapore is similar to that of Northern Europe. This paper describes how this current generation of older Singaporean women aged 65 and above experiences declines in health status and well-being as they age. Their vulnerability is the higher risk of chronic illnesses stemming from longer life expectancy and a lower likelihood of access to appropriate health and social care. This is because health and social care in old age are mainly financed by individual out-of-pocket spending which includes support from adult children. Unlike Northern Europe, Singapore does not yet have a well-developed social welfare system to support women in old age.     

The role of Chinese face in the perpetration of dating partner violence

This study explored the associations between the perpetration of partner violence and two types of face orientation-protective and acquisitive-in Chinese societies. Data from a convenience sample of 3,388 university students from Hong Kong, Shanghai, and Beijing were analyzed. The participants completed the Protective and Acquisitive Face Orientation (PAFO) Scale Short Form and the Revised Conflict Tactics Scale (CTS2) to measure their face orientations and experience of perpetrating violence against their dating partner. Acquisitive face orientation (AFO) was positively associated with the self-reported perpetration of physical and psychological partner violence. No significant associations were found between protective face orientation (PFO) and partner violence perpetration. Gender differences were found across all types of dating violence. City of residence, age, and SES were also associated with partner violence in specific ways. The findings gave insights on the possible mechanisms between partner violence and the concept of face to be explored in future research.     

Gender symmetry in the self-reporting of intimate partner violence

Research has not conclusively determined whether men and women are equally likely to commit intimate partner violence (IPV). One explanation for the disparity in previous findings may be gender-based differences in reporting styles. The present study investigated whether there was any gender difference in self-reported IPV prevalence. A total of 3,740 Chinese couples from a representative population in Hong Kong were interviewed. Self-reports of men-to-women and women-to-men IPV between spouses were compared. Gender was controlled for to evaluate whether age, education, the Chinese concept of face, and other violence-related characteristics would affect the self-reporting of IPV. Findings supported gender symmetry in self-reported IPV prevalence as well as a moderate interspousal agreement in the self-reports. After adjustment for covariates, face was a significant factor predicting the interspousal differences in both men-to-women and women-to-men physical IPV.     

借力第三方市场 推进泛北部湾合作

发展中国家和地区参与区域经济合作的实践表明,"南—北"("弱—强")型合作模式成功机率较高。广西与东盟应立足现有基础,联手引进欧美日韩等发达国家的资金、技术和人才等,努力提升"弱—弱"型为主的合作模式,开辟一条借力第三方市场、推进泛北部湾经济合作的新路径。如利用中国—东盟博览会合作平台、打好区域性招商组合牌、主动切入发达国家跨国公司价值链分工体系、加大对发达国家中小企业引进力度等。     

Precarity and Vulnerability: Rubber Plantations in Northern Laos and Northern Shan State,Myanmar

ABSTRACT

In northern Laos and Northern Shan State in Myanmar, there has occurred a rapid expansion of rubber plantations, both by large economic concessions and by smallholder farmers. The impact of the introduction of rubber differs by place. This article analyses the impact of the introduction of rubber in two villages in Northern Shan State and two in Luang Namtha Province, Lao PDR. We differentiate vulnerability and precarity while assessing the changes that women and men have experienced, which allows us to problematise the long-term vulnerability of seemingly well-adapted farming households. We argue that the strategies that farmers have chosen to improve their situation today will lead to unsustainable livelihoods in the long term. We also link the analysis of vulnerability and precarity to changes in household gender relations. Notwithstanding increased precarity, rising household cash incomes and external support have improved women’s position in some places while hardly affecting gender relations in others.     

Simultaneous analysis of d-3-methoxy-17-methylmorphinan and l-3-methoxy-17-methylmorphinan by high pressure liquid chromatography equipped with PDA

d-3-Methoxy-17-methylmorphinan (Dextromethorphan, DXM), which is a structural analog of morphine and codeine, has been widely used as a non-narcotic antitussive agent. It is a safe drug in therapeutic dose and does not produce analgesic effects, while its enantiomer, l-3-methoxy-17-methylmorphinan called levomethorphan (LXM) is a potent narcotic analgesic. DXM has been widely abused in Korea due to its hallucinogenic effect in large doses; therefore, the health authorities have regulated its use as a psychotropic agent since 2003. As its abuse has been serious, a possibility that DXM would be smuggled into Korea has also increased. Moreover, it has been suspected that there was the possibility of the adulteration or substitution of DXM with LXM due to their chemical similarities. Therefore, it was necessary for us to establish the enantiomeric separation of DXM and LXM. In this study, a liquid chromatographic method using a chiral column capable of separating stereoisomers of DXM as well as analyzing the major metabolites of DXM, 3-methoxymorphinan, 3-hydroxymorphinan, and 17-hydroxymethylmorphinan was developed. The validation of a method was studied through repeatability of retention times. Using this method, 32 confiscated DXM samples were analyzed to identify the enantiomers of DXM. As a result, DXM was detected in all samples and there was no evidence of the adulteration or substitution of DXM with LXM. Nevertheless, the stereochemical analysis of DXM and LXM is important not only to identify starting materials for illegal drug manufacture but also to understand the trends of abused drugs.