Understanding incidental findings in the context of genetics and genomics.

Human genetic and genomic research can yield information that may be of clinical relevance to the individuals who participate as subjects of the research. It has been common practice among researchers to notify participants during the informed consent process that no individual results will be disclosed, "incidental" or otherwise. However, as genetic information obtained in research becomes orders of magnitude more voluminous, increasingly accessible online, and more informative, this precedent may no longer be appropriate. There is not yet consensus on the responsibilities of researchers to disclose individual research results to research participants. Empirical research suggests that participants want to know individual research results. On the other hand, the increased resolution and power afforded by new genomic analyses may lead to findings of statistical, but not necessarily clinical, significance. This paper addresses the issues to be considered in deciding whether and how to disclose "incidental" findings or other findings of clinical significance that arise in the course of human genomic and genetic research. What research results should be offered, and what should not be offered? For which research should individual results be offered to research participants, when should they be offered, how, and to whom?     

From rule-taker to rule-promoting regulatory state: South Korea in the nearly-global competition regime

When rapid economic growth catapults a country within a few years from the margins of the global economy to middle power status, does global regulatory governance need to brace for a challenge to the status quo? To answer this question, we extend the power transition theory of global economic governance to middle powers: A rising middle power should be expected to challenge the international regulatory status quo only if increasing issue-specific strength of its regulatory state coincides with preferences that diverge from the preferences of the established powers, which are enshrined in the status quo. We examine this argument empirically, focusing on South Korea in the realm of competition law and policy. We find that South Korea, a non-participant in the international competition regime until the 1980s, developed in the 1990s substantial regulatory capacity and capability and thus “spoiler potential.” At the same time, however, its policy preferences converged upon the norms and practices established by the United States and the European Union, albeit with some distinct elements. Under these conditions, we expect a transition from rule-taker to rule-promoter. We find that South Korea has indeed in recent years begun to actively promote well-established competition law and policy norms and practices – supplemented by its distinct elements – through technical assistance programs, as well as various bilateral channels and multilateral institutions. The findings suggest that the power transition theory of global economic governance is usefully applicable to middle powers, too.     

Raising Seoul's global competitiveness: developing key performance indicators

This paper develops a set of key performance indicators (KPIs) for Seoul city administration, inaugurated in 2006. Proper establishment and application of the KPIs into its administration would not only help in accomplishing municipal leadership's strategic initiations but also enhance Seoul's global competitiveness. At the same time, the KPIs can be a good communication tool through which the leadership and city customers can communicate with each other.     

Procedural justice and perceived electoral integrity: the case of Korea's 2012 presidential election

Recently, there has been an increase in the number of scholars focusing on why voters around the world differ in their evaluations of electoral integrity. One group of scholars contends that perceived electoral integrity is determined by partisan status according to election results. Another group claims that individual perception of election quality is influenced by such political cues as institutional support for election management bodies. Although the two groups have developed this subject differently, they both underestimate the degree to which the election process affects electoral integrity. Based on the theory of procedural justice, this study argues that the more problems citizens see in the electoral process, the more negatively they tend to rate elections. An analysis of a public opinion survey conducted immediately after the December 2012 presidential election in South Korea provides credible evidence for our theoretical expectations and presents an important implication for elections of new democracies in a comparative perspective.     

Application of Volume‐of‐Fluid Method to Analyze the Viscosity Effect on the Spine Formation of Bloodstains

In bloodstain pattern analysis, the blood droplet volume and surface impact velocity play an important role, and many related experimental studies have been carried out. If an appropriate computational fluid dynamics (CFD) model that could solve bloodstain patterns, especially spine formation bloodstain patterns, can be obtained, the blood droplet volume and impact speeds at various crime scenes can be predicted more accurately. For this purpose, Flow‐3D software using the volume‐of‐fluid method was applied to analyze the behavior of human blood droplets during an impact event, especially focusing on the viscous effect on splashing, which forms the spine which can be used to predict the impact velocity. To obtain a non‐Newtonian viscosity model of blood for a computational fluid dynamic analysis, the venous blood samples of 163 people were tested using a hemorheology instrument. Among the venous blood samples of 163 people, 37 samples for which all blood test results were in a normal range were selected for the non‐Newtonian viscosity modeling. From the CFD analysis, it could be concluded that a non‐Newtonian viscosity model is more appropriate than a constant viscosity model for predicting splashing that forms the spine. The gradient of the non‐Newtonian model at a high shear rate has more of an effect on spine formation than that at a low shear rate. The lowest viscosity with a high velocity at the outer front of the radiating flow plays an important role in forming the splashing pattern.     

Human Trafficking,A Shadow of Migration – Evidence from Germany

This paper investigates relationship between migration and human trafficking in Germany by analyzing macro-level data from 150 countries. The empirical results suggest that migrant networks of a specific source country pull human trafficking from that respective country. However, the migration effect varies across different income levels of source countries. The positive effect of migration on human trafficking decreases as income increases, and furthermore, the effect is irrelevant to high income countries. In addition, the migration effect is particularly significant on the criminalisation side of human trafficking, but the evidence is less clear when it concerns the victimisation side.     

How well ordinary citizens understand democracy: the case of the South Korean electorate

How do mass citizens understand democracy? Are they capable of distinguishing it from its non-democratic alternatives? Does their understanding about democracy matter? To reveal the contours of cultural democratization in South Korea, this article addresses these questions largely overlooked in earlier survey-based studies. Analyses of the 2010 Korea Barometer survey indicate that all segments of the Korean electorate, including the young and the college-educated, are neither accurately nor fully informed about what distinguishes a democratic regime from its non-democratic alternatives. Moreover, the study provides strong evidence of democratic learning in that an increase in democratic knowledge leads to committed support for democracy. The findings together imply an urgent need to improve the quality of civic education for the development of democratic political culture in Korea and new democracies.     

A Ferris Wheel Accident at a Movable Amusement Park

This study presented a Ferris wheel accident case. A Ferris wheel is composed of many parts, and the outmost ring of it is assembled using a lock pin. This accident occurred because the lock pin caught the door of a gondola and the gondola overturned. Five of the seven passengers in the gondola fell to the ground, along with the gondola's viewing window. The investigation revealed that the gondola became stuck when its door was caught by a lock pin at the Ferris wheel's three o'clock position. The contact between the door and the lock pin was due to a structural problem: There was not enough space allotted between the door and the lock pin. Therefore, if a passenger pushed on the gondola's door, the potential existed for contact between the door and the lock pin.     

Population data of nine miniSTR loci in Koreans

For highly degraded DNA samples of forensic casework, new miniSTR systems have been developed to supplement the current STR systems. In the present study, nine miniSTR loci were analyzed in 300 unrelated Koreans using three multiplex PCR systems (multiplex I: D10S1248, D14S1434 and D22S1045; multiplex II: D1S1677, D2S441 and D4S2364; and multiplex III: D3S3053, D6S474 and D20S482), and allele frequencies and forensic parameters were calculated. These data demonstrated that D10S1248, D2S441, D22S1045, D14S1434, and D6S474 are as highly informative as the CODIS STRs suggesting that the miniSTRs could be useful for forensic analysis of degraded DNA.