A single-column procedure on Bond Elut Certify for systematic toxicological analysis of drugs in plasma and urine.

A single-column solid-phase extraction procedure was developed for the screening of acidic, neutral, and basic drugs from plasma. The recoveries of all 25 tested drugs exceeded 82%. After the plasma had been diluted with phosphate buffer (pH 6.0), the drugs were extracted using a single Bond Elut Certify column. The acidic and most of the neutral drugs were eluted by acetone/chloroform (1:1) and the basic drugs were eluted by 2% ammoniated ethyl acetate. Some neutral drugs appeared in both fractions. The two fractions were collected separately and evaporated until approximately 100 microL of solvent remained in the tube. Both fractions were analyzed separately on a gas chromatograph equipped with a wide-bore capillary column and a flame ionization detector. The procedure could also be used for urine samples.     

猪传染性胸膜肺炎三价灭活疫苗的研究--菌种选择、疫苗制备及安全性试验

以国内多发的猪传染性胸膜肺炎放线杆菌 (APP) 1、3、7血清型强毒株作为制苗菌株 ,制成油佐剂三价灭活苗。经效力试验 ,对上述 3种血清型强毒攻击的保护率分别为 88.8%、88.8%和 10 0 % ;试验动物安全性检验及田间安全检验 ,除个别猪出现轻微体温反应及暂时减食外 ,无其他异常反应。表明该苗对猪的保护性及安全性良好     

The emotional motivation of righteous behavior

A distinction is made between two types of prosocial behavior: personal-helping and righteous behavior. Past studies suggest that sympathy may motivate personal helping but not righteous behavior. The latter may be better predicted by feelings of moral outrage and existential guilt. An experiment was designed to motivate a piece of righteous behavior, the writing of a political letter to stop the testing of nuclear weapons. A series of premeasures ascertained strength of attitude, sense of efficacy, acceptance of responsibility, and prior antinuclear behavior. Subjects who supported a nuclear freeze were exposed to material advocating a nuclear test ban, a video of a congressional aide who argued for the efficacy of writing letters to congressional representatives, and emotionally arousing material on the bombing of Hiroshima. After answering a questionnaire that included items to measure emotional state, subjects were individually given the opportunity to write a letter as they were waiting to be interviewed. Social pressure was deliberately minimized. Extent of moral outrage predicted both previous behavior and letter-writing behavior during the experiment. It combined with previous behavior and sense of efficacy to predict 56% of the variance in experimental behavior: Neither sympathy nor existential guilt were significantly related to this righteous behavior.     

Multicenter evaluation of ultrafiltration, dialysis, and thermal coagulation as sample pretreatment methods for the colorimetric determination of paraquat in blood and tissues

Three methods of sample pretreatment for the rapid colorimetric determination of paraquat were compared: ultrafiltration, dialysis, and thermal coagulation. Spiked autopsy blood and tissue samples were examined in parallel in Groningen and Krakow and some samples were interchanged. All three methods gave recoveries between 87 to 102%; accuracy at the 20-mg/L level was within 10% of the target value and coefficients of variation in the 10 to 60-mg/L range were between 3 to 15%. Determinations in blood and liver in a fatal case of Gramoxone poisoning showed excellent agreement. Because of its reliability, speed, and simplicity, ultrafiltration is the method of choice.     

The Suzhou industrial park experiment: the case of China–Singapore governmental collaboration

This paper examines the Suzhou Industrial Park project, a collaborative venture between the China and Singapore governments between 1992 and 2002. The collaboration represented a convergence of the two governments' development strategies. The aim was to jointly benefit from foreign direct investment (FDI) by attracting industrial transnational corporations to locate operations within the Park. To achieve this, the China government invested strong political support for the project, while the Singapore government invested capital and administrative expertise. This paper finds that between 1992 and 1997, the collaboration was relatively successful, as the Suzhou Industrial Park experienced some of the highest levels of foreign direct investment in China. However, between 1997 and 1999, the project faced several problems including the effects of the Asian Financial Crisis outside China and competition from other industrial estates within China. This ultimately led the Singapore government to announce its disengagement from the project in June 1999. This paper concludes with some observations about inter-governmental collaboration as a new form of development strategy.