Compulsory treatment with clozapine: a retrospective long-term cohort study

BACKGROUND: Clozapine is the gold standard in treatment of treatment-resistant psychotic patients. We know little about the effects of compulsory treatment in patients unwilling to accept the necessary treatment. AIMS: To assess the effectiveness, tolerability and safety of compulsory treatment with clozapine (CTC). METHOD: A cohort of 17 consecutive patients given compulsory treatment with clozapine were rated retrospectively by their treating psychiatrists on the basis of their case notes. RESULTS: CGI-S decreased significantly over time until last observation after a mean of more than 15 months. No patient deteriorated as measured by CGI-I. At last observation as many as ten of the 11 patients still on clozapine were classified as much to very much improved. The degree of custodial restriction at last observation showed improvement in 11 patients and no change in six. No serious adverse events were observed. CONCLUSION: A trial of compulsory treatment with clozapine showed this treatment to be feasible, effective, safe and well tolerated.     

Measuring Reed’s Reach: Content Discrimination in the U.S. Circuit Courts of Appeals After Reed v. Town of Gilbert

Commentators and justices on the Supreme Court of the United States speculated when the Court delivered its opinion in Reed v. Town of Gilbert in 2015 that the case would dramatically reshape First Amendment law. This article analyzes Reed’s impact to date in the United States Circuit Courts of Appeals. The article demonstrates that, although Reed has been consequential in some circuits, it has not been the basis of any First Amendment revolution. Indeed, the research supports the conclusion that many circuit courts seem to be actively working to narrow Reed’s reach. Moreover, the article concludes that Reed did little to clarify — and in some ways made worse — what has been a problematic doctrine for decades.     

Enter the quagmire – the complicated relationship between data protection law and consumer protection law

This article examines the complex relationship between consumer protection law and data protection law, particularly within the EU's online environment, and highlights the problems that stem from this complexity. It suggests that, while there are significant similarities between their respective sources, tools and purposes, there are also arguable differences between consumer protection law and data protection law. One such arguable difference is found in that, while consumer protection law can be seen to merely set a floor in its pursuit of a sufficiently high level of consumer protection, data protection law – due to its clearly articulated dual purposes of (a) protecting individuals with regard to the processing of personal data and (b) providing for the free movement of such data – sets both a floor and a ceiling.Having discussed the relationship between consumer protection law and data protection law in more detail, the argument is made that it seems possible to conclude that the balance struck in the Data Protection Directive, and soon in the General Data Protection Regulation, places limitations on consumer protection law. The implications of this conclusion are then examined briefly in the context of some matters currently coming before the CJEU and the contours of a framework are presented, addressing situations where a data protection-based liability claim is pursued against a third-party non-controller under consumer protection law.     

痔瘘熏洗剂治疗火毒炽盛型低位肛周脓肿术后创面临床观察

目的 观察痔瘘熏洗剂熏洗治疗火毒炽盛型低位肛周脓肿切开引流术后创面的临床疗效.方法 将40例患者按1∶1原则随机分为治疗组和对照组,治疗组20例采用痔瘘熏洗剂熏洗治疗,对照组20例用皮肤康洗剂熏洗治疗.3周后评价疗效.结果 治疗组在减少创面渗液、加快腐肉脱落、促进创面愈合方面明显优于治疗组(P<0.05,或P<0.01...     

丁锷运用虫类药物治疗骨伤科疑难病证经验

丁锷是安徽省骨伤科著名老中医,对骨伤科疑难病证的治疗积累了丰富的临床经验,在辨证论治基础上擅长运用虫类药,形成了自己的风格,创制了多个验方.其运用虫类药物治疗骨伤科疾病如颈椎病、腰椎间盘突出症、强直性脊柱炎、股骨头坏死、化脓性骨髓炎,疗效显著.     

二元劳动力市场背景下就业质量的提升机制研究 ——基于 CLDS 数据的实证分析

中国城市劳动力市场的二元分割背景下,劳动者的就业质量提升机制呈现出一定的差异性。研 究基于资本和职业流动视角,利用中国劳动力动态调查（CLDS）数据,多重考察和检验不同劳动力市场影响劳 动者就业质量提升的因素。研究发现：首要劳动力市场就业者的知识人力资本、弱关系型社会资本、干部职位 政治资本对提升就业质量有积极作用,次要劳动力市场就业者通过提升知识人力资本、技术人力资本、弱关系 型社会资本、干部职位政治资本提升就业质量;首要劳动力市场就业者通过主动、自愿的职业流动实现就业质 量的提升,次要劳动力市场就业者通过增加职业流动次数有效提升就业质量;资本因素对首要劳动力市场就业 者通过职业流动提升就业质量不具有抑制作用,但一定程度上会抑制次要劳动力市场就业者通过职业流动提升 就业质量的作用。因此,要充分了解劳动者的诉求与真实就业状况,帮助次要劳动力市场就业者增加资本 ( 人力 资本、社会资本、政治资本 ) 的投入和积累,以提升其就业质量。     

补肾安胎冲剂联合免疫疗法治疗反复自然流产40例

目的 观察补肾安胎冲剂联合免疫疗法治疗反复自然流产(recurrent spontaneous abortion,RSA)的临床疗效.方法 收集封闭抗体低下型RSA患者80例,随机分成综合治疗组、单纯淋巴细胞治疗对照组各40例,对照组采用丈夫淋巴细胞皮下注射主动免疫疗法;综合治疗组在对照组基础上加服补肾安胎冲剂,比较治...